ChemInform Abstract: Pyridine Hydrochloride: A New Reagent for the Synthesis of o- Chlorohydroxy Derivatives in Pyridine and Quinoline Series.

ChemInform ◽  
2010 ◽  
Vol 27 (51) ◽  
pp. no-no
Author(s):  
F. MONGIN ◽  
O. MONGIN ◽  
F. TRECOURT ◽  
A. GODARD ◽  
G. QUEGUINER
Keyword(s):  
Pyridine Hydrochloride ◽  
Quinoline Series

Pyridine hydrochloride: a new reagent for the synthesis of o-chloro hydroxy derivatives in pyridine and quinoline series

1996 ◽  
Vol 37 (37) ◽  
pp. 6695-6698 ◽  
Author(s):  
Florence Mongin ◽  
Olivier Mongin ◽  
François Trécourt ◽  
Alain Godard ◽  
Guy Quéguiner
Keyword(s):  
Pyridine Hydrochloride ◽  
Quinoline Series

Potential antidepressants: Synthesis of two 4-(aminoalkoxy)dibenzo[b,e]thiepin-11(6H)-ones

1989 ◽  
Vol 54 (1) ◽  
pp. 225-228 ◽  
Author(s):  
Irena Červená ◽  
Jiří Holubek ◽  
Emil Svátek ◽  
Jan Metyš ◽  
Martin Valchář ◽  
...  
Keyword(s):  
Sodium Salt ◽  
Anticonvulsant Effect ◽  
Rat Hypothalamus ◽  
Pyridine Hydrochloride ◽  
Antihypoxic Effect

Heating of 4-methoxydibenzo[b,e]thiepin-11(6H)-one with pyridine hydrochloride to 225 to 235 °C effected demethylation and gave IV. Its sodium salt reacted with 3-dimethylaminopropyl chloride in ethanol and afforded the 4-(3-dimethylaminopropoxy) compound II. The isomeric ether III was prepared via the 4-(4-bromobutoxy) compound V. Hydrochloride of II (VÚFB-17 033) inhibited mildly the binding of [3H]desipramine in rat hypothalamus, had antireserpine activity in rats, mild anticonvulsant effect, and antihypoxic effect in the test of nitrogen anoxia in mice.

Paramagnetic derivatives in the hydrogenated quinoline series

1965 ◽  
Vol 14 (6) ◽  
pp. 1069-1071 ◽  
Author(s):  
A. B. Shapiro ◽  
E. G. Rozantsev ◽  
L. S. Povarov ◽  
V. I. Grigos
Keyword(s):  
Quinoline Series

scholarly journals Synthetic Studies in Quinoline Series. V

1953 ◽  
Vol 73 (3) ◽  
pp. 293-294
Author(s):  
Masaiti Yasue
Keyword(s):  
Quinoline Series ◽  
Synthetic Studies

scholarly journals The antiseptic and trypanocidal action of certain styryl and anil benzthiazole derivatives

1931 ◽  
Vol 108 (755) ◽  
pp. 119-129 ◽  
Keyword(s):  
Pyridine Ring ◽  
Membered Ring ◽  
Present Series ◽  
Quinoline Derivatives ◽  
Present Communication ◽  
Quinoline Series ◽  
Derivatives Of

In view of the powerful antiseptic action of certain anil quinoline compounds (Browning, Cohen, Ellingworth and Gulbransen, 1926) and the trypanocidal action of these and especially of some styryl quinoline derivatives (Browning, Cohen, Ellingworth and Gulbransen, 1929), it was thought desirable to examine the action of similar compounds containing other heterocyclic nuclei. The present communication is concerned with a number of derivatives of benzthiazole, in which the pyridine ring of the quinoline group is replaced by a five-membered ring containing both nitrogen and sulphur. Antiseptic Action . Antiseptic power was estimated as in previous communications (Browning, Cohen, Elingworth and Gulbransen, 1926, 1928). Throughout the range of the anil benzthiazole compounds examined the antiseptic activity is considerably lower than that of the corresponding quinoline compounds. The styryl compounds tend also to be weak in their antiseptic action and in this respect resemble the styryl quinoline series, but in general they are not inferior to the latter in potency. Frequently in the present series of compounds the irregularities in action, previously commented upon, were observed in marked degree.

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