ChemInform Abstract: The Enantioselective Total Synthesis of the Antitumor Macrolide Natural Product Rhizoxin D.

ChemInform ◽  
2010 ◽  
Vol 30 (32) ◽  
pp. no-no
Author(s):  
Jennifer A. Lafontaine ◽  
David P. Provencal ◽  
Cristina Gardelli ◽  
James W. Leahy
Keyword(s):  
Total Synthesis ◽  
Natural Product ◽  
Enantioselective Total Synthesis ◽  
Rhizoxin D

The enantioselective total synthesis of the antitumor macrolide natural product rhizoxin D

1999 ◽  
Vol 40 (22) ◽  
pp. 4145-4148 ◽  
Author(s):  
Jennifer A. Lafontaine ◽  
David P. Provencal ◽  
Cristina Gardelli ◽  
James W. Leahy
Keyword(s):  
Total Synthesis ◽  
Natural Product ◽  
Enantioselective Total Synthesis ◽  
Rhizoxin D

A concise enantioselective total synthesis of rhizoxin D

2002 ◽  
Vol 43 (3) ◽  
pp. 493-497 ◽  
Author(s):  
Ian S. Mitchell ◽  
Gerald Pattenden ◽  
Jeffrey P. Stonehouse
Keyword(s):  
Total Synthesis ◽  
Enantioselective Total Synthesis ◽  
Rhizoxin D

Enantioselective total synthesis of periconiasin A

2018 ◽  
Vol 5 (5) ◽  
pp. 838-840 ◽  
Author(s):  
Zhixiong Zeng ◽  
Cheng Chen ◽  
Yandong Zhang
Keyword(s):  
Total Synthesis ◽  
Natural Product ◽  
Enantioselective Total Synthesis

A concise, enantioselective total synthesis of periconiasin A, a hybrid natural product, has been achieved.

ChemInform Abstract: First Enantioselective Total Synthesis of (-)-Dysibetaine CPa and Absolute Configurations of Natural Product

ChemInform ◽  
2014 ◽  
Vol 45 (9) ◽  
pp. no-no
Author(s):  
Michihiro Sakai ◽  
Yuichi Ishikawa ◽  
Satoshi Takamizawa ◽  
Masato Oikawa
Keyword(s):  
Total Synthesis ◽  
Natural Product ◽  
Enantioselective Total Synthesis

Enantioselective total synthesis of (S)-nakinadine B

RSC Advances ◽  
2016 ◽  
Vol 6 (31) ◽  
pp. 25913-25917 ◽  
Author(s):  
Yuvraj Garg ◽  
Satyendra Kumar Pandey
Keyword(s):  
Total Synthesis ◽  
Natural Product ◽  
Michael Addition ◽  
Marine Natural Product ◽  
Enantioselective Total Synthesis ◽  
Novel Approach ◽  
Key Steps

A novel approach for the synthesis of (S)-nakinadine B, a marine natural product is described. The synthesis utilizes the optimized combination of organocatalyzed Michael addition and aminoxylation reactions as key steps.

Total Synthesis of (–)-Aristoquinoline via an Intramolecular Nitrilium Ion Cyclization

Synthesis ◽  
2021 ◽  
Author(s):  
Keith P. Reber ◽  
Priyansh D. Gujarati
Keyword(s):  
Total Synthesis ◽  
Natural Product ◽  
Building Block ◽  
Spectroscopic Properties ◽  
Ring System ◽  
Synthetic Route ◽  
Enantioselective Total Synthesis ◽  
Key Steps

AbstractThe enantioselective total synthesis of the alkaloid aristoquinoline has been achieved in seven steps and 26% overall yield. A new preparation of the useful synthetic building block (–)-α-terpinyl amine was also developed in order to avoid stoichiometric mercury reagents or azide-containing intermediates. Key steps in the optimized synthetic route include an intramolecular nitrilium ion cyclization to form the characteristic azabicyclo[3.3.1]nonane ring system and a dia­stereoselective reduction of the resulting imine mixture to afford the natural product. An isomer of aristoquinoline containing an exocyclic alkene was also obtained and found to exhibit unusual chromatographic and spectroscopic properties.

Sign in / Sign up

Export Citation Format

Share Document