New Radical Scavenging and Ultraviolet-A Protecting Prenylated Dioxopiperazine Alkaloid Related to Isoechinulin A from a Marine Isolate of the Fungus Aspergillus.

ChemInform ◽  
2004 ◽  
Vol 35 (46) ◽  
Author(s):  
Yong Li ◽  
Xifeng Li ◽  
Jung Sook Kang ◽  
Hong Dae Choi ◽  
Byeng Wha Son
2008 ◽  
Vol 61 (1) ◽  
pp. 40-42 ◽  
Author(s):  
Dahai Zhang ◽  
Xiudong Yang ◽  
Jung Sook Kang ◽  
Hong Dae Choi ◽  
Byeng Wha Son
Keyword(s):  

ChemInform ◽  
2008 ◽  
Vol 39 (31) ◽  
Author(s):  
Dahai Zhang ◽  
Xiudong Yang ◽  
Jung Sook Kang ◽  
Hong Dae Choi ◽  
Byeng Wha Son
Keyword(s):  

ChemInform ◽  
2006 ◽  
Vol 37 (47) ◽  
Author(s):  
Yong Li ◽  
Xifeng Li ◽  
Uk Lee ◽  
Jung Sook Kang ◽  
Hong Dae Choi ◽  
...  

2006 ◽  
Vol 54 (6) ◽  
pp. 882-883 ◽  
Author(s):  
Yong Li ◽  
Xifeng Li ◽  
Uk Lee ◽  
Jung Sook Kang ◽  
Hong Dae Choi ◽  
...  

2017 ◽  
Vol 14 (4) ◽  
pp. 1475-1484 ◽  
Author(s):  
Noble Kiriyachan Kurian ◽  
Sarita Ganapathy Bhat

ABSTRACT: Photoprotection and Anti-inflammatory properties of characterized melanin produced by marine proteobacterium Providencia rettgeri strain BTKKS1 was explored in the study. Characterization of melanin was carried out by chemical, FTIR, proton NMR and EPR analysis. The radical scavenging property was estimated using DPPH assay and Fe 2+ chelating potential was also evaluated. Effect of melanin on the activities of Cyclooxygenase, Lipoxygenase, Myeloperoxidase and Cellular Nitrite is used to evaluate anti-inflammatory potential. Enhancement of Sun Protection Factor (SPF) is evaluated to study its effectiveness in photoprotection. Cytotoxicity of melanin was estimated using MTT assay.The chemical, FTIR, proton NMR and EPR characterization were typical of eumelanin. The pigment also showed profound radical scavenging activity (63.73%) and metal chelating potential (97.09%). Melanin significantly inhibited the activity of the inflammatory enzymes in a dose dependent manner and enhanced the SPF value of commercial sunscreens at an average of 2.64 factors. This melanin was also less cytotoxic with an IC50 value of 97.87μg/mL. The immense Anti-inflammatory property of the pigment can be utilized in therapeutic applications. The photoprotection potential of melanin can be utilized in cosmetic formulations, UV protection devices etc.


Author(s):  
Delma P. Thomas ◽  
Dianne E. Godar

Ultraviolet radiation (UVR) from all three waveband regions of the UV spectrum, UVA (320-400 nm), UVB (290-320 nm), and UVC (200-290 nm), can be emitted by some medical devices and consumer products. Sunlamps can expose the blood to a considerable amount of UVR, particularly UVA and/or UVB. The percent transmission of each waveband through the epidermis to the dermis, which contains blood, increases in the order of increasing wavelength: UVC (10%) < UVB (20%) < UVA (30%). To investigate the effects of UVR on white blood cells, we chose transmission electron microscopy to examine the ultrastructure changes in L5178Y-R murine lymphoma cells.


1998 ◽  
Vol 138 (6) ◽  
pp. 1100-1101 ◽  
Author(s):  
Wolf ◽  
SchOllnast ◽  
Hofer ◽  
Smolle ◽  
Kerl

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