Enantioselective Synthesis of Primary 1-(Aryl)alkylamines by Nucleophilic 1,2-Addition of Organolithium Reagents to Hydroxyoxime Ethers and Application to Asymmetric Synthesis of G-Protein-Coupled Receptor Ligands.

Organolithium Reagents ◽

Enantioselective Synthesis of Primary 1-(Aryl)alkylamines by Nucleophilic 1,2-Addition of Organolithium Reagents to Hydroxyoxime Ethers and Application to Asymmetric Synthesis of G-Protein-Coupled Receptor Ligands

The Journal of Organic Chemistry ◽

10.1021/jo049517+ ◽

2004 ◽

Vol 69 (17) ◽

pp. 5595-5607 ◽

Cited By ~ 47

Author(s):

Masakazu Atobe ◽

Naoki Yamazaki ◽

Chihiro Kibayashi

Keyword(s):

Asymmetric Synthesis ◽

G Protein ◽

Enantioselective Synthesis ◽

Receptor Ligands ◽

Organolithium Reagents ◽

A New Strategy for Asymmetric Synthesis Exploiting Oxime Ethers and Application to Enantioselective Syntheses of G-Protein-Coupled Receptor Ligands

19th International Congress on Heterocyclic Chemistry ◽

10.1016/b978-0-08-044304-1.50106-4 ◽

2003 ◽

pp. 114

Author(s):

Masakazu Atobe ◽

Naoki Yamazaki ◽

Chihiro Kibayashi

Keyword(s):

Asymmetric Synthesis ◽

G Protein ◽

Receptor Ligands ◽

New Strategy ◽

G Protein Coupled ◽

Enantioselective Syntheses

Fancy Bioisosteres: Metallocene-Derived G-Protein-Coupled Receptor Ligands with Subnanomolar Binding Affinity and Novel Selectivity Profiles

Journal of Medicinal Chemistry ◽

10.1021/jm050170s ◽

2005 ◽

Vol 48 (11) ◽

pp. 3696-3699 ◽

Cited By ~ 47

Author(s):

Karin Schlotter ◽

Frank Boeckler ◽

Harald Hübner ◽

Peter Gmeiner

Keyword(s):

G Protein ◽

Binding Affinity ◽

Receptor Ligands ◽

Nucleoligands-repurposing G Protein–coupled Receptor Ligands to Modulate Nuclear-localized G Protein–coupled Receptors in the Cardiovascular System

Journal of Cardiovascular Pharmacology ◽

10.1097/fjc.0000000000000535 ◽

2018 ◽

Vol 71 (4) ◽

pp. 193-204 ◽

Cited By ~ 3

Author(s):

Nicolas Audet ◽

Rabah Dabouz ◽

Bruce G. Allen ◽

Terence E. Hébert

Keyword(s):

Cardiovascular System ◽

G Protein ◽

G Protein Coupled Receptors ◽

Receptor Ligands ◽

Pharmacogenomics of G Protein-Coupled Receptor Ligands in Cardiovascular Medicine

Pharmacological Reviews ◽

10.1124/pr.108.000612 ◽

2008 ◽

Vol 60 (4) ◽

pp. 513-535 ◽

Cited By ~ 26

Author(s):

Dieter Rosskopf ◽

Martin C. Michel

Keyword(s):

G Protein ◽

Receptor Ligands ◽

Cardiovascular Medicine ◽

Electrostatically-driven fast association and perdeuteration allow detection of transferred cross-relaxation for G protein-coupled receptor ligands with equilibrium dissociation constants in the high-to-low nanomolar range

Journal of Biomolecular NMR ◽

10.1007/s10858-011-9523-3 ◽

2011 ◽

Vol 50 (3) ◽

pp. 191-195 ◽

Cited By ~ 15

Author(s):

Laurent J. Catoire ◽

Marjorie Damian ◽

Marc Baaden ◽

Éric Guittet ◽

Jean-Louis Banères

Keyword(s):

G Protein ◽

Dissociation Constants ◽

Cross Relaxation ◽

Receptor Ligands ◽

Equilibrium Dissociation Constants ◽

Equilibrium Dissociation ◽

G Protein Coupled ◽

Nanomolar Range

ERK1/2 Mediate Wounding- and G-protein-Coupled Receptor Ligands-Induced EGFR Activation via Regulating ADAM17 and HB-EGF Shedding

Investigative Opthalmology & Visual Science ◽

10.1167/iovs.08-2246 ◽

2009 ◽

Vol 50 (1) ◽

pp. 132 ◽

Cited By ~ 37

Author(s):

Jia Yin ◽

Fu-Shin X. Yu

Keyword(s):

G Protein ◽

Receptor Ligands ◽

Egfr Activation ◽

Transactivation of Trk Neurotrophin Receptors by G-Protein-Coupled Receptor Ligands Occurs on Intracellular Membranes

Journal of Neuroscience ◽

10.1523/jneurosci.0010-04.2004 ◽

2004 ◽

Vol 24 (30) ◽

pp. 6650-6658 ◽

Cited By ~ 179

Author(s):

R. Rajagopal

Keyword(s):

G Protein ◽

Neurotrophin Receptors ◽

Receptor Ligands ◽

Intracellular Membranes ◽

Novel G-Protein Coupled Receptor Ligands and Neurohypophysial Hormones

Journal of Neuroendocrinology ◽

10.1111/j.0953-8194.2004.01179.x ◽

2004 ◽

Vol 16 (4) ◽

pp. 378-382 ◽

Cited By ~ 2

Author(s):

Y. Ueta ◽

Y. Ozaki ◽

J. Saito

Keyword(s):

G Protein ◽

Receptor Ligands ◽

Neurohypophysial Hormones ◽

Quo vadis G protein-coupled receptor ligands? A tool for analysis of the emergence of new groups of compounds over time

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2016.12.001 ◽

2017 ◽

Vol 27 (3) ◽

pp. 626-631 ◽

Cited By ~ 4

Author(s):

Damian Leśniak ◽

Stanisław Jastrzębski ◽

Sabina Podlewska ◽

Wojciech M. Czarnecki ◽

Andrzej J. Bojarski

Keyword(s):

G Protein ◽

Receptor Ligands ◽

Quo Vadis ◽

G Protein Coupled ◽

Over Time