Reaction Between Isocyanides and Dialkyl Acetylenedicarboxylates in the Presence of 4,5-Diphenyl-1,3-dihydro-2H-imidazol-2-one. One-Pot Synthesis of 5H-Imidazo[2,1-b][1,3]oxazine Derivatives.

ChemInform ◽  
2005 ◽  
Vol 36 (29) ◽  
Author(s):  
Mehdi Adib ◽  
Khadijeh Ghanbary ◽  
Manizheh Mostofi ◽  
Hamid Reza Bijanzadeh
1999 ◽  
Vol 23 (6) ◽  
pp. 368-369
Author(s):  
Issa Yavari ◽  
Abbas Ali Esmaili ◽  
Sakineh Asghari ◽  
Hamid Reza Bijanzadeh

The highly reactive 1:1 intermediate produced in the reaction between tert-butyl isocyanide and dialkyl acetylenedicarboxylates is trapped by dialkyl 2-bromomalonates to yield the title compounds in fairly high yields.


2012 ◽  
Vol 36 (7) ◽  
pp. 398-401 ◽  
Author(s):  
Mudumala Veeranarayana Reddy ◽  
Kwon Taek Lim ◽  
Jong Tae Kim ◽  
Yeon Tae Jeong

2012 ◽  
Vol 9 (4) ◽  
pp. 2239-2244 ◽  
Author(s):  
Hossein Anaraki-Ardakani ◽  
Maziar Noei ◽  
Mina Karbalaei-Harofteh ◽  
Shahab Zomorodbakhsh

A new and efficient one-pot synthesis of polysubstituted pyrrole derivatives by three-component reaction between dialkyl acetylenedicarboxylates, triphenylphosphine, 2-aminopyridin derivatives in the presence of arylglyoxals is described. The reactions were performed in dichloromethane at room temperature and neutral conditions and afforded high yields of products.


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