ChemInform Abstract: DNA Binding, Photocleavage, and Topoisomerase Inhibition of Functionalized Ruthenium(II)-Polypyridine Complexes

ChemInform ◽  
2009 ◽  
Vol 40 (3) ◽  
Author(s):  
Feng Gao ◽  
Hui Chao ◽  
Liang-Nian Ji
Keyword(s):  
Dna Binding ◽  
Topoisomerase Inhibition ◽  
Polypyridine Complexes

DNA binding and Topoisomerase inhibition: How can these mechanisms be explored to design more specific anticancer agents?

2017 ◽  
Vol 96 ◽  
pp. 1538-1556 ◽  
Author(s):  
Sinara Mônica Vitalino de Almeida ◽  
Amélia Galdino Ribeiro ◽  
Geilza Carla de Lima Silva ◽  
Josival Emanuel Ferreira Alves ◽  
Eduardo Isidoro Carneiro Beltrão ◽  
...  
Keyword(s):  
Dna Binding ◽  
Anticancer Agents ◽  
Topoisomerase Inhibition

Synthesis, DNA binding and topoisomerase inhibition of mononaphthalimide homospermidine derivatives

2008 ◽  
Vol 19 (5) ◽  
pp. 509-512 ◽  
Author(s):  
Zhi Yong Tian ◽  
Hong Xia Ma ◽  
Song Qiang Xie ◽  
Xue Wang ◽  
Jin Zhao ◽  
...  
Keyword(s):  
Dna Binding ◽  
Topoisomerase Inhibition

scholarly journals Synthesis, characterization, DNA binding, topoisomerase inhibition, and apoptosis induction studies of a novel cobalt(III) complex with a thiosemicarbazone ligand

2020 ◽  
Vol 203 ◽  
pp. 110907 ◽  
Author(s):  
Stephen J. Beebe ◽  
Michael J. Celestine ◽  
Jimmie L. Bullock ◽  
Shayna Sandhaus ◽  
Jessa Faye Arca ◽  
...  
Keyword(s):  
Dna Binding ◽  
Apoptosis Induction ◽  
Topoisomerase Inhibition ◽  
Thiosemicarbazone Ligand

scholarly journals DNA Interactions with Ruthenium(II) Polypyridine Complexes Containing Asymmetric Ligands

2005 ◽  
Vol 3 (1-2) ◽  
pp. 15-28 ◽  
Author(s):  
Hui Chao ◽  
Liang-Nian Ji
Keyword(s):  
Nucleic Acid ◽  
Dna Binding ◽  
Binding Modes ◽  
Dna Interactions ◽  
Binding Properties ◽  
The Past ◽  
Polypyridine Complexes ◽  
Nucleic Acid Structures ◽  
Dna Binding Properties ◽  
Shape And Size

In an attempt to probe nucleic acid structures, numerous Ru(II) complexes with different ligands have been synthesized and investigated. In this contribution we focus on the DNA-binding properties of ruthenium(II) complexes containing asymmetric ligands that have attracted little attention in the past decades. The influences of the shape and size of the ligand on the binding modes, affinity, enantioselectivities and photocleavage of the complexes to DNA are described.

scholarly journals Synthesis, DNA Binding, Topoisomerase Inhibition and Cytotoxic Properties of 2-Chloroethylnitrosourea Derivatives of Hoechst 33258

2005 ◽  
Vol 28 (6) ◽  
pp. 1004-1009 ◽  
Author(s):  
Krzysztof Bielawski ◽  
Anna Bielawska ◽  
Tomasz Anchim ◽  
Sławomir Wołczyński
Keyword(s):  
Dna Binding ◽  
Hoechst 33258 ◽  
Topoisomerase Inhibition ◽  
Derivatives Of

scholarly journals DNA binding, topoisomerase inhibition and cytotoxicity of palladium(II) complexes with 1,10-phenanthroline and thioureas

2016 ◽  
Vol 446 ◽  
pp. 54-60 ◽  
Author(s):  
Carolina V. Barra ◽  
Fillipe V. Rocha ◽  
Laurent Morel ◽  
Arnaud Gautier ◽  
Saulo S. Garrido ◽  
...  
Keyword(s):  
Dna Binding ◽  
Topoisomerase Inhibition
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