A copper-catalyzed [2+3] annulation of N–H imines with vinyl azides to generate polyaryl 2H-imidazoles with N2 and H2O as the only by-products has been developed.
A visible-light-mediated tandem sulfonylation/cyclization of vinyl azides with sulfonyl hydrazines was developed that provides an efficient and simple strategy for the synthesis of valuable 6-(sulfonylmethyl)phenanthridines with a broad substrate scope and satisfactory yields under mild conditions.
The reaction protocol is operationally simple and conducted under an aerobic atmosphere, allowing highly functionalized α-azido-β-fluoronitriles bearing a quaternary carbon to be furnished, that are difficult to access by existing methods.
Tandem Michael addition and Witting or Horner–Wadsworth–Emmons olefination initiated [3+3] annulation between vinyl azides and allylic phosphorus ylides or allylic phosphoryl-stabilized carbanions has been developed.
