ChemInform Abstract: Rhodium-Catalyzed Asymmetric Addition of Arylboronic Acids to β-Nitroolefins: Formal Synthesis of (S)-SKF 38393.

ChemInform ◽  
2014 ◽  
Vol 45 (14) ◽  
pp. no-no
Author(s):  
Kung-Chih Huang ◽  
Balraj Gopula ◽  
Ting-Shen Kuo ◽  
Chien-Wei Chiang ◽  
Ping-Yu Wu ◽  
...  
Keyword(s):  
Skf 38393 ◽  
Asymmetric Addition ◽  
Formal Synthesis ◽  
Arylboronic Acids

Rhodium-Catalyzed Asymmetric Addition of Arylboronic Acids to β-Nitroolefins: Formal Synthesis of (S)-SKF 38393

2013 ◽  
Vol 15 (22) ◽  
pp. 5730-5733 ◽  
Author(s):  
Kung-Chih Huang ◽  
Balraj Gopula ◽  
Ting-Shen Kuo ◽  
Chien-Wei Chiang ◽  
Ping-Yu Wu ◽  
...  
Keyword(s):  
Skf 38393 ◽  
Asymmetric Addition ◽  
Formal Synthesis ◽  
Arylboronic Acids

Synthesis of Solution-Phase Phosphoramidite and Phosphite Ligand Libraries and Their In Situ Screening in the Rhodium-Catalyzed Asymmetric Addition of Arylboronic Acids

2007 ◽  
Vol 9 (3) ◽  
pp. 407-414 ◽  
Author(s):  
Richard B. C. Jagt ◽  
Patrick Y. Toullec ◽  
Ebe P. Schudde ◽  
Johannes G. de Vries ◽  
Ben L. Feringa ◽  
...  
Keyword(s):  
Solution Phase ◽  
Asymmetric Addition ◽  
Arylboronic Acids

Rhodium-Catalyzed Asymmetric Addition of Arylboronic Acids to Glyoxylates: Access to Optically Active Substituted Mandelic Acid Esters

Synlett ◽  
2019 ◽  
Vol 30 (14) ◽  
pp. 1693-1697
Author(s):  
Diao Chen ◽  
Jian-Guo Liu ◽  
Xu Zhang ◽  
Ming-Hua Xu
Keyword(s):  
Catalytic System ◽  
Mandelic Acid ◽  
Optically Active ◽  
Antiplatelet Drug ◽  
Reaction Conditions ◽  
Formal Synthesis ◽  
Arylboronic Acids ◽  
Synthetic Utility ◽  
Enantioselective Addition ◽  
Acid Esters

A rhodium-catalyzed enantioselective addition of glyoxylates to arylboronic acids promoted by a simple chiral sulfinamide-based olefin ligand under mild reaction conditions is described. The reaction provides access to a variety of optically active substituted mandelic acid esters in good yields with up to 83% ee. The catalytic system is also applicable to pyruvate addition. The synthetic utility of this method is highlighted by a formal synthesis of the antiplatelet drug clopidogrel.

Ni(ii)-catalyzed asymmetric addition of arylboronic acids to cyclic imines

2017 ◽  
Vol 53 (3) ◽  
pp. 609-612 ◽  
Author(s):  
Mao Quan ◽  
Liang Tang ◽  
Jiaqi Shen ◽  
Guoqiang Yang ◽  
Wanbin Zhang
Keyword(s):  
Asymmetric Addition ◽  
Arylboronic Acids

A Ni(ii)-catalyzed asymmetric addition of arylboronic acids to cyclic imines has been realized using a tropos biphenyl phosphine-oxazoline ligand.

scholarly journals Chiral Sulfinyl-Based Olefin Ligands for Rhodium-Catalysed Asymmetric Conjugate Addition of Arylboronic Acids to Cyanoalkenes

2018 ◽  
Vol 42 (6) ◽  
pp. 300-304 ◽  
Author(s):  
Feng Xue ◽  
Yong Zhu ◽  
Xiaolei Qi
Keyword(s):  
Conjugate Addition ◽  
Asymmetric Addition ◽  
Arylboronic Acids ◽  
Catalytic Asymmetric

A rhodium/sulfinyl-based olefin ligand-catalysed asymmetric conjugate addition of arylboronic acids to cyanoalkenes without activation groups has been developed, where p-tolylsulfinyl-functionalised olefin ligands have been shown to be effective and with moderate enantioselectivities. This is the first example of applying chiral sulfinyl-based olefin ligands in the catalytic asymmetric addition to cyanoalkenes.

tert-Butanesulfinylphosphines: Simple Chiral Ligands in Rhodium-Catalyzed Asymmetric Addition of Arylboronic Acids to Electron-Deficient Olefins

2010 ◽  
Vol 352 (5) ◽  
pp. 843-846 ◽  
Author(s):  
Feng Lang ◽  
Dong Li ◽  
Junmin Chen ◽  
Jun Chen ◽  
Liangchun Li ◽  
...  
Keyword(s):  
Chiral Ligands ◽  
Asymmetric Addition ◽  
Arylboronic Acids
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