ChemInform Abstract: Sulfur-Carbon Bond Formation Through Ring-Opening of Triazolothiadiazole with Organometallics.

ChemInform ◽  
2015 ◽  
Vol 46 (6) ◽  
pp. no-no
Author(s):  
Raja Ben Othman ◽  
Stephane Massip ◽  
Mathieu Marchivie ◽  
Christian Jarry ◽  
Johnny Vercouillie ◽  
...  
Tetrahedron ◽  
2014 ◽  
Vol 70 (33) ◽  
pp. 4942-4946 ◽  
Author(s):  
Stig Holden Christensen ◽  
Torkil Holm ◽  
Robert Madsen

2014 ◽  
Vol 2014 (15) ◽  
pp. 3225-3231 ◽  
Author(s):  
Raja Ben Othman ◽  
Stéphane Massip ◽  
Mathieu Marchivie ◽  
Christian Jarry ◽  
Johnny Vercouillie ◽  
...  

Tetrahedron ◽  
2004 ◽  
Vol 60 (16) ◽  
pp. 3593-3597 ◽  
Author(s):  
Franck Meyer ◽  
Abdelhamid Laaziri ◽  
Anna Maria Papini ◽  
Jacques Uziel ◽  
Sylvain Jugé

ChemInform ◽  
2014 ◽  
Vol 45 (51) ◽  
pp. no-no
Author(s):  
Stig Holden Christensen ◽  
Torkil Holm ◽  
Robert Madsen

2018 ◽  
Author(s):  
Mohit Kapoor ◽  
Pratibha Chand-Thakuri ◽  
Michael Young

Carbon-carbon bond formation by transition metal-catalyzed C–H activation has become an important strategy to fabricate new bonds in a rapid fashion. Despite the pharmacological importance of <i>ortho</i>-arylbenzylamines, however, effective <i>ortho</i>-C–C bond formation from C–H bond activation of free primary and secondary benzylamines using Pd<sup>II</sup> remains an outstanding challenge. Presented herein is a new strategy for constructing <i>ortho</i>-arylated primary and secondary benzylamines mediated by carbon dioxide (CO<sub>2</sub>). The use of CO<sub>2</sub> is critical to allowing this transformation to proceed under milder conditions than previously reported, and that are necessary to furnish free amine products that can be directly used or elaborated without the need for deprotection. In cases where diarylation is possible, a chelate effect is demonstrated to facilitate selective monoarylation.


Author(s):  
Jie Jack Li ◽  
Chris Limberakis ◽  
Derek A. Pflum

Searching for reaction in organic synthesis has been made much easier in the current age of computer databases. However, the dilemma now is which procedure one selects among the ocean of choices. Especially for novices in the laboratory, it becomes a daunting task to decide what reaction conditions to experiment with first in order to have the best chance of success. This collection intends to serve as an "older and wiser lab-mate" one could have by compiling many of the most commonly used experimental procedures in organic synthesis. With chapters that cover such topics as functional group manipulations, oxidation, reduction, and carbon-carbon bond formation, Modern Organic Synthesis in the Laboratory will be useful for both graduate students and professors in organic chemistry and medicinal chemists in the pharmaceutical and agrochemical industries.


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