ChemInform Abstract: Design and Synthesis of Fused Polycycles via Diels-Alder Reaction and Ring-Rearrangement Metathesis as Key Steps.

ChemInform ◽  
2015 ◽  
Vol 46 (43) ◽  
pp. no-no
Author(s):  
Sambasivarao Kotha ◽  
Ongolu Ravikumar
Keyword(s):  
Alder Reaction ◽  
Diels Alder ◽  
Design And Synthesis ◽  
Diels Alder Reaction ◽  
Key Steps

scholarly journals Design and synthesis of C 3-symmetric molecules bearing propellane moieties via cyclotrimerization and a ring-closing metathesis sequence

2018 ◽  
Vol 14 ◽  
pp. 2537-2544 ◽  
Author(s):  
Sambasivarao Kotha ◽  
Saidulu Todeti ◽  
Vikas R Aswar
Keyword(s):  
Benzene Ring ◽  
Alder Reaction ◽  
Diels Alder ◽  
Central Core ◽  
Ring Closing Metathesis ◽  
Design And Synthesis ◽  
Synthetic Strategy ◽  
Diels Alder Reaction ◽  
End Groups ◽  
Key Steps

We have developed an efficient synthetic strategy to assemble C 3-symmetric molecules containing propellane moieties as end groups and a benzene ring as a central core. The synthesis of these C 3-symmetric molecules involves simple starting materials. Our approach to C 3-symmetric compounds relies on a Diels–Alder reaction, cyclotrimerization and ring-closing metathesis as key steps.

scholarly journals Design and synthesis of polycyclic sulfones via Diels–Alder reaction and ring-rearrangement metathesis as key steps

2015 ◽  
Vol 11 ◽  
pp. 1373-1378 ◽  
Author(s):  
Sambasivarao Kotha ◽  
Rama Gunta
Keyword(s):  
Alder Reaction ◽  
Diels Alder ◽  
Ring Systems ◽  
Design And Synthesis ◽  
Synthetic Strategy ◽  
Diels Alder Reaction ◽  
Fused Ring ◽  
Materials Used ◽  
Key Steps

Here, we describe a new and simple synthetic strategy to various polycyclic sulfones via Diels–Alder reaction and ring-rearrangement metathesis (RRM) as the key steps. This approach delivers tri- and tetracyclic sulfones with six (n = 1), seven (n = 2) or eight-membered (n = 3) fused-ring systems containing trans-ring junctions unlike the conventional all cis-ring junctions generally obtained during the RRM sequence. Interestingly the starting materials used are simple and commercially available.

scholarly journals Design and synthesis of fused polycycles via Diels–Alder reaction and ring-rearrangement metathesis as key steps

2015 ◽  
Vol 11 ◽  
pp. 1259-1264 ◽  
Author(s):  
Sambasivarao Kotha ◽  
Ongolu Ravikumar
Keyword(s):  
Alder Reaction ◽  
Diels Alder ◽  
Design And Synthesis ◽  
Diels Alder Reaction ◽  
Grignard Addition ◽  
Synthetic Routes ◽  
Key Steps ◽  
Norbornene Derivatives

Atom efficient processes such as the Diels–Alder reaction (DA) and the ring-rearrangement metathesis (RRM) have been used to design new polycycles. In this regard, ruthenium alkylidene catalysts are effective in realizing the RRM of bis-norbornene derivatives prepared by DA reaction and Grignard addition. Here, fused polycycles are assembled which are difficult to produce by conventional synthetic routes.

Exploratory synthetic investigations related to 12a-deoxypillaromycinone

2002 ◽  
Vol 80 (6) ◽  
pp. 728-738 ◽  
Author(s):  
Lan Wang ◽  
Sanath K Meegalla ◽  
Cheng-Lin Fang ◽  
Nicholas Taylor ◽  
Russell Rodrigo
Keyword(s):  
Double Bond ◽  
Catalytic Hydrogenation ◽  
Alder Reaction ◽  
Diels Alder ◽  
Diels Alder Reaction ◽  
Step Procedure ◽  
Key Steps

Furfural is converted to suitably substituted AB synthon 21 for 12a-deoxypillaromycinone in 10 steps by a sequence involving the following key steps: intramolecular Diels-Alder reaction of a furan, 5-endo-trig cleavage of the oxabicyclo adducts 18, and catalytic hydrogenation of the double bond of a tetrasubstituted enone to produce 19. Enones 21a and 21b obtained by dehydrogenation of 19a and 19b, respectively, are then annulated with ethyl 2-methoxy-6-methylbenzoate in a four-step procedure to generate tetracyclic products 25 in 14 steps from furfural.

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