ChemInform Abstract: Catalytic Asymmetric Construction of Spiro[pyrrolidine-2,3′-oxindole] Scaffolds Through Chiral Phosphoric Acid-Catalyzed 1,3-Dipolar Cycloaddition Involving 3-Amino Oxindoles.

ChemInform ◽  
2016 ◽  
Vol 47 (8) ◽  
pp. no-no
Author(s):  
Guodong Zhu ◽  
Baomin Wang ◽  
Xiaoze Bao ◽  
Huanrui Zhang ◽  
Qian Wei ◽  
...  
2015 ◽  
Vol 51 (85) ◽  
pp. 15510-15513 ◽  
Author(s):  
Guodong Zhu ◽  
Baomin Wang ◽  
Xiaoze Bao ◽  
Huanrui Zhang ◽  
Qian Wei ◽  
...  

The catalytic asymmetric three-component 1,3-dipolar cycloaddition of 3-amino oxindoles with aldehydes and nitroolefins with a chiral phosphoric acid is reported.


ChemInform ◽  
2016 ◽  
Vol 47 (21) ◽  
Author(s):  
Zhenhua Zhang ◽  
Wangsheng Sun ◽  
Gongming Zhu ◽  
Junxian Yang ◽  
Ming Zhang ◽  
...  

2015 ◽  
Vol 13 (29) ◽  
pp. 7993-8000 ◽  
Author(s):  
Yu-Xin Gong ◽  
Qiong Wu ◽  
Hong-Hao Zhang ◽  
Qiu-Ning Zhu ◽  
Feng Shi

A chiral phosphoric acid-catalyzed asymmetric reaction of 2-indolylmethanols with 3-alkylindoles has been established to construct 2,2′-bisindolylmethane scaffold in good enantioselectivities.


2016 ◽  
Vol 52 (7) ◽  
pp. 1377-1380 ◽  
Author(s):  
Zhenhua Zhang ◽  
Wangsheng Sun ◽  
Gongming Zhu ◽  
Junxian Yang ◽  
Ming Zhang ◽  
...  

The first chiral phosphoric acid catalyzed highly diastereo- and enantioselective 1,3-dipolar cycloaddition reaction of azlactones and methyleneindolinones was disclosed to yield 3,3′-pyrrolidonyl spirooxindole scaffolds.


2017 ◽  
Vol 15 (22) ◽  
pp. 4794-4797 ◽  
Author(s):  
Can Li ◽  
Han Lu ◽  
Xiao-Xue Sun ◽  
Guang-Jian Mei ◽  
Feng Shi

A chiral phosphoric acid-catalyzed asymmetric [3 + 3] cycloaddition of C3-substituted 2-indolylmethanols with isatin-derived azomethine ylides has been established, which afforded chiral spirooxindoles in considerable yields, moderate to good stereoselectivities.


2018 ◽  
Vol 16 (30) ◽  
pp. 5457-5464 ◽  
Author(s):  
Jia-Le Wu ◽  
Cong-Shuai Wang ◽  
Jin-Rong Wang ◽  
Guang-Jian Mei ◽  
Feng Shi

A chiral phosphoric acid-catalyzed asymmetric interrupted Nazarov-type cyclization of C3-alkenyl-substituted 2-indolylmethanols has been established by using cyclic enaminones as nucleophiles.


2020 ◽  
Vol 11 (3) ◽  
pp. 671-676 ◽  
Author(s):  
Xihong Liu ◽  
Jingying Zhang ◽  
Lutao Bai ◽  
Linqing Wang ◽  
Dongxu Yang ◽  
...  

The first chiral phosphoric acid catalyzed asymmetric multiple dearomatizations of phenols for the synthesis of bridged polycyclic compounds are reported.


Synlett ◽  
2013 ◽  
Vol 24 (06) ◽  
pp. 661-665 ◽  
Author(s):  
Pavel Nagorny ◽  
Zhankui Sun ◽  
Grace Winschel

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