Synthesis and Pharmacological Evaluation of 8- and 9-Substituted Benzolactam-V8 Derivatives as Potent Ligands for Protein Kinase C, a Therapeutic Target for Alzheimer's Disease

ChemMedChem ◽  
2006 ◽  
Vol 1 (3) ◽  
pp. 307-314 ◽  
Author(s):  
Ulrich R. Mach ◽  
Nancy E. Lewin ◽  
Peter M. Blumberg ◽  
Alan P. Kozikowski
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Protein Kinase C ◽  
Protein Kinase ◽  
Therapeutic Target ◽  
Pharmacological Evaluation ◽  
Kinase C

Attenuated protein kinase C activity and translocation in Alzheimer's Disease brain

1994 ◽  
Vol 15 (3) ◽  
pp. 293-298 ◽  
Author(s):  
Hoau-Yan Wang ◽  
Michael R. Pisano ◽  
Eitan Friedman
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Protein Kinase C ◽  
Protein Kinase ◽  
Kinase C ◽  
Protein Kinase C Activity

scholarly journals Decreased level of Protein Kinase C in brains with ALZHEIMER'S DISEASE.

1991 ◽  
Vol 55 ◽  
pp. 225
Author(s):  
Mitsuhiro Narita ◽  
Takashi Taniguchi ◽  
Shun Shimohama ◽  
Jun Kimura
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Protein Kinase C ◽  
Protein Kinase ◽  
Kinase C

Protein Kinase C Anchoring Deficit in Postmortem Brains of Alzheimer's Disease Patients

1999 ◽  
Vol 159 (2) ◽  
pp. 559-564 ◽  
Author(s):  
Fiorenzo Battaini ◽  
Alessia Pascale ◽  
Laura Lucchi ◽  
Giulio M. Pasinetti ◽  
Stefano Govoni
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Protein Kinase C ◽  
Protein Kinase ◽  
Kinase C ◽  
Postmortem Brains
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