Largazole Analogues as Histone Deacetylase Inhibitors and Anticancer Agents: An Overview of Structure-Activity Relationships

The design, synthesis and structure–activity relationships of novel isoindoline-based histone deacetylase inhibitors

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2011.06.015 ◽

2011 ◽

Vol 21 (16) ◽

pp. 4909-4912 ◽

Cited By ~ 17

Author(s):

Michael Shultz ◽

Jianmei Fan ◽

Christine Chen ◽

Young Shin Cho ◽

Nicole Davis ◽

...

Keyword(s):

Histone Deacetylase ◽

Design Synthesis ◽

Histone deacetylase inhibitors (HDACIs). Structure-activity relationships: history and new QSAR perspectives

Medicinal Research Reviews ◽

10.1002/med.20200 ◽

2010 ◽

Vol 32 (1) ◽

pp. 1-165 ◽

Cited By ~ 52

Author(s):

Eleni Pontiki ◽

Dimitra Hadjipavlou-Litina

Keyword(s):

Histone Deacetylase ◽

Histone Deacetylase Inhibitors: Design, Structure-Activity Relationships and Therapeutic Implications for Cancer

Anti-Cancer Agents in Medicinal Chemistry ◽

10.2174/187152009788679976 ◽

2009 ◽

Vol 9 (6) ◽

pp. 661-692 ◽

Cited By ~ 44

Author(s):

Charles Marson

Keyword(s):

Histone Deacetylase ◽

Therapeutic Implications ◽

Structure Activity ◽

Design Structure

Histone Deacetylase Inhibitors: A New Wave of Molecular Targeted Anticancer Agents

Recent Patents on Anti-Cancer Drug Discovery ◽

10.2174/157489207780832450 ◽

2007 ◽

Vol 2 (2) ◽

pp. 119-134 ◽

Cited By ~ 33

Author(s):

Alfredo Budillon ◽

Elena Di Gennaro ◽

Francesca Bruzzese ◽

Monia Rocco ◽

Giuseppe Manzo ◽

...

Keyword(s):

Histone Deacetylase ◽

Anticancer Agents ◽

New Wave

1,3,4-Oxadiazole-containing Hybrids as Potential Anticancer Agents: Recent Developments, Mechanism of Action and Structure-Activity Relationships

Journal of Saudi Chemical Society ◽

10.1016/j.jscs.2021.101284 ◽

2021 ◽

pp. 101284

Author(s):

Swarnagowri Nayak ◽

Santosh L. Gaonkar ◽

Ebraheem Abdu Musad ◽

Abdullah Mohammed AL. Dawsar

Keyword(s):

Mechanism Of Action ◽

Anticancer Agents ◽

Structure Activity ◽

Recent Developments

Structure–activity relationships of hydroxamate-based histone deacetylase-8 inhibitors: reality behind anticancer drug discovery

Future Medicinal Chemistry ◽

10.4155/fmc-2017-0130 ◽

2017 ◽

Vol 9 (18) ◽

pp. 2211-2237 ◽

Cited By ~ 21

Author(s):

Sk Abdul Amin ◽

Nilanjan Adhikari ◽

Tarun Jha

Keyword(s):

Drug Discovery ◽

Histone Deacetylase ◽

Anticancer Drug ◽

Structure Activity ◽

Histone Deacetylase 8 ◽

Anticancer Drug Discovery

Back Cover: Photochemical Properties and Structure-Activity Relationships of RuII Complexes with Pyridylbenzazole Ligands as Promising Anticancer Agents (Eur. J. Inorg. Chem. 12/2017)

European Journal of Inorganic Chemistry ◽

10.1002/ejic.201700259 ◽

2017 ◽

Vol 2017 (12) ◽

pp. 1842-1842

Author(s):

Dmytro Havrylyuk ◽

David K. Heidary ◽

Leona Nease ◽

Sean Parkin ◽

Edith C. Glazer

Keyword(s):

Anticancer Agents ◽

Back Cover ◽

Structure Activity ◽

Photochemical Properties

Selective and effective anticancer agents: Synthesis, biological evaluation and structure-activity relationships of novel carbazole derivatives

Bioorganic Chemistry ◽

10.1016/j.bioorg.2021.104991 ◽

2021 ◽

pp. 104991

Author(s):

Wenbo Huang ◽

Zilin Gao ◽

Zhigang Zhang ◽

Wei Fang ◽

Zuoqian Wang ◽

...

Keyword(s):

Anticancer Agents ◽

Biological Evaluation ◽

Carbazole Derivatives ◽

Broad spectrum antiprotozoal agents that inhibit histone deacetylase: structure–activity relationships of apicidin. Part 1

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/s0960-894x(00)00604-1 ◽

2001 ◽

Vol 11 (2) ◽

pp. 107-111 ◽

Cited By ~ 45

Author(s):

Steven L Colletti ◽

Robert W Myers ◽

Sandra J Darkin-Rattray ◽

Anne M Gurnett ◽

Paula M Dulski ◽

...

Keyword(s):

Histone Deacetylase ◽

Broad Spectrum ◽

Combining Histone Deacetylase Inhibitors with Other Anticancer Agents as a Novel Strategy for Circumventing Limited Therapeutic Efficacy and Mitigating Toxicity

Histone Deacetylase Inhibitors in Combinatorial Anticancer Therapy ◽

10.1007/978-981-15-8179-3_10 ◽

2020 ◽

pp. 203-239

Author(s):

Shabir Ahmad Ganai

Keyword(s):

Histone Deacetylase ◽

Anticancer Agents ◽

Therapeutic Efficacy ◽

Novel Strategy