Histogenesis of the substantia nigra, ventral tegmental area of Tsai and interpeduncular nucleus: An autoradiographic study of the mesencephalon in the rat

1971 ◽  
Vol 142 (1) ◽  
pp. 59-73 ◽  
Author(s):  
Joseph Hanaway ◽  
Jo Ann McConnell ◽  
Martin G. Netsky
Keyword(s):  
Substantia Nigra ◽  
Ventral Tegmental Area ◽  
Autoradiographic Study ◽  
Interpeduncular Nucleus ◽  
Ventral Tegmental

The electrophysiological actions of dopamine and dopaminergic drugs on neurons of the substantia nigra pars compacta and ventral tegmental area

Life Sciences ◽  
1992 ◽  
Vol 51 (10) ◽  
pp. 711-718 ◽  
Author(s):  
Nicola B. Mercuri ◽  
Paolo Calabresi ◽  
Giorgio Bernardi
Keyword(s):  
Substantia Nigra ◽  
Ventral Tegmental Area ◽  
Substantia Nigra Pars Compacta ◽  
Dopaminergic Drugs ◽  
Ventral Tegmental

The Evolving Understanding of Dopamine Neurons in the Substantia Nigra and Ventral Tegmental Area

2018 ◽  
Vol 80 (1) ◽  
pp. 219-241 ◽  
Author(s):  
Stephanie C. Gantz ◽  
Christopher P. Ford ◽  
Hitoshi Morikawa ◽  
John T. Williams
Keyword(s):  
Substantia Nigra ◽  
Ventral Tegmental Area ◽  
Dopamine Neurons ◽  
Ventral Tegmental

ALDH1 mRNA: presence in human dopamine neurons and decreases in substantia nigra in Parkinson's disease and in the ventral tegmental area in schizophrenia

2003 ◽  
Vol 14 (3) ◽  
pp. 637-647 ◽  
Author(s):  
Dagmar Galter ◽  
Silvia Buervenich ◽  
Andrea Carmine ◽  
Maria Anvret ◽  
Lars Olson
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Substantia Nigra ◽  
Ventral Tegmental Area ◽  
Dopamine Neurons ◽  
Ventral Tegmental

Cardiovascular depressor responses to stimulation of substantia nigra and ventral tegmental area

1997 ◽  
Vol 273 (6) ◽  
pp. H2549-H2557 ◽  
Author(s):  
Gilbert J. Kirouac ◽  
John Ciriello
Keyword(s):  
Substantia Nigra ◽  
Ventral Tegmental Area ◽  
Intravenous Administration ◽  
Dopaminergic Neurons ◽  
Cardiovascular Responses ◽  
Receptor Blocker ◽  
Transitional Region ◽  
Pars Lateralis ◽  
Ventral Tegmental ◽  
Stimulation Of

Experiments were done in α-chloralose-anesthetized, paralyzed, and artificially ventilated rats to investigate the effect ofl-glutamate (Glu) stimulation of the substantia nigra (SN) and ventral tegmental area (VTA) on arterial pressure (AP) and heart rate (HR). Glu stimulation of the SN pars compacta (SNC) elicited decreases in both mean AP (MAP; −18.9 ± 1.3 mmHg; n = 52) and HR (−26.1 ± 1.6 beats/min; n = 46) at 81% of the sites stimulated. On the other hand, stimulation of the SN pars lateralis or pars reticulata did not elicit cardiovascular responses. Stimulation of the adjacent VTA region elicited similar decreases in MAP (−18.0 ± 2.6 mmHg; n = 20) and HR (−25.4 ± 3.8 beats/min; n = 17) at ∼74% of the sites stimulated. Intravenous administration of the dopamine D2-receptor antagonist raclopride significantly attenuated both the MAP (70%) and the HR (54%) responses elicited by stimulation of the transitional region where the SNC merges with the lateral VTA (SNC-VTA region). Intravenous administration of the muscarinic receptor blocker atropine methyl bromide had no effect on the magnitude of the MAP and HR responses to stimulation of the SNC-VTA region, whereas administration of the nicotinic receptor blocker hexamethonium bromide significantly attenuated both the depressor and the bradycardic responses. These data suggest that dopaminergic neurons in the SNC-VTA region activate a central pathway that exerts cardiovascular depressor effects that are mediated by the inhibition of sympathetic vasoconstrictor fibers to the vasculature and cardioacceleratory fibers to the heart.

Dopamine Biosynthesis Is Selectively Abolished in Substantia Nigra/Ventral Tegmental Area but Not in Hypothalamic Neurons in Mice with Targeted Disruption of the Nurr1 Gene

1998 ◽  
Vol 11 (1-2) ◽  
pp. 36-46 ◽  
Author(s):  
Susan O. Castillo ◽  
Judit S. Baffi ◽  
Miklós Palkovits ◽  
David S. Goldstein ◽  
Irwin J. Kopin ◽  
...  
Keyword(s):  
Substantia Nigra ◽  
Ventral Tegmental Area ◽  
Hypothalamic Neurons ◽  
Targeted Disruption ◽  
Dopamine Biosynthesis ◽  
Ventral Tegmental

A histochemical examination of the metabolic profiles of rat ventral tegmental area and substantia nigra arterioles

1986 ◽  
Vol 64 (1) ◽  
pp. 91-96
Author(s):  
M.Samuel Cannon ◽  
Evelyn D. Kapes ◽  
Michael E. Trulson
Keyword(s):  
Substantia Nigra ◽  
Ventral Tegmental Area ◽  
Metabolic Profiles ◽  
Ventral Tegmental ◽  
Histochemical Examination
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