Physiologically based pharmacokinetic modelling to investigate the impact of the cytokine storm on CYP3A drug pharmacokinetics in COVID‐19 patients

Clinical Pharmacology & Therapeutics ◽

10.1002/cpt.2402 ◽

2021 ◽

Author(s):

Felix Stader ◽

Manuel Battegay ◽

Parham Sendi ◽

Catia Marzolini

Keyword(s):

Cytokine Storm ◽

Pharmacokinetic Modelling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based Pharmacokinetic Modelling ◽

Physiologically Based ◽

Drug Pharmacokinetics

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Physiologically based pharmacokinetic modelling of acetaminophen in preterm neonates ‐ the impact of metabolising enzyme ontogeny and reduced cardiac output

Biopharmaceutics & Drug Disposition ◽

10.1002/bdd.2301 ◽

2021 ◽

Author(s):

Olusola Olafuyi ◽

Mohammad Abbasi ◽

Karel Allegaert

Keyword(s):

Cardiac Output ◽

Preterm Neonates ◽

Pharmacokinetic Modelling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based Pharmacokinetic Modelling ◽

Physiologically Based ◽

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The application of physiologically based pharmacokinetic modelling to assess the impact of antiretroviral-mediated drug-drug interactions on piperaquine antimalarial therapy during pregnancy

Biopharmaceutics & Drug Disposition ◽

10.1002/bdd.2087 ◽

2017 ◽

Vol 38 (8) ◽

pp. 464-478 ◽

Author(s):

Olusola Olafuyi ◽

Michael Coleman ◽

Raj K.S. Badhan

Keyword(s):

Drug Interactions ◽

Pharmacokinetic Modelling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based Pharmacokinetic Modelling ◽

Antimalarial Therapy ◽

Physiologically Based ◽

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Physiologically based pharmacokinetic modelling to support the clinical management of drug‐drug interactions with bictegravir

Clinical Pharmacology & Therapeutics ◽

10.1002/cpt.2221 ◽

2021 ◽

Author(s):

Felix Stader ◽

Manuel Battegay ◽

Catia Marzolini

Keyword(s):

Drug Interactions ◽

Clinical Management ◽

Pharmacokinetic Modelling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based Pharmacokinetic Modelling ◽

Physiologically Based

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Prediction of olanzapine exposure in individual patients using physiologically based pharmacokinetic modelling and simulation

British Journal of Clinical Pharmacology ◽

10.1111/bcp.13480 ◽

2018 ◽

Vol 84 (3) ◽

pp. 462-476 ◽

Author(s):

Thomas M. Polasek ◽

Geoffrey T. Tucker ◽

Michael J. Sorich ◽

Michael D. Wiese ◽

Titus Mohan ◽

...

Keyword(s):

Modelling And Simulation ◽

Pharmacokinetic Modelling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based Pharmacokinetic Modelling ◽

Physiologically Based

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Physiologically based pharmacokinetic modelling: a sub-compartmentalized model of tissue distribution

Journal of Pharmacokinetics and Pharmacodynamics ◽

10.1007/s10928-007-9071-3 ◽

2007 ◽

Vol 34 (6) ◽

pp. 789-806 ◽

Author(s):

Max von Kleist ◽

Wilhelm Huisinga

Keyword(s):

Tissue Distribution ◽

Pharmacokinetic Modelling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based Pharmacokinetic Modelling ◽

Physiologically Based

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Physiologically‐based pharmacokinetic modelling to predict oprozomib CYP3A drug–drug interaction potential in patients with advanced malignancies

British Journal of Clinical Pharmacology ◽

10.1111/bcp.13817 ◽

2018 ◽

Vol 85 (3) ◽

pp. 530-539 ◽

Author(s):

Ying Ou ◽

Yang Xu ◽

Lia Gore ◽

R. Donald Harvey ◽

Alain Mita ◽

...

Keyword(s):

Drug Interaction ◽

Interaction Potential ◽

Pharmacokinetic Modelling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based Pharmacokinetic Modelling ◽

Advanced Malignancies ◽

Physiologically Based ◽

Drug Drug Interaction

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Development of a Korean‐specific virtual population for physiologically based pharmacokinetic modelling and simulation

Biopharmaceutics & Drug Disposition ◽

10.1002/bdd.2178 ◽

2019 ◽

Vol 40 (3-4) ◽

pp. 135-150 ◽

Author(s):

Yun Kim ◽

Oliver Hatley ◽

Su‐jin Rhee ◽

Sojeong Yi ◽

Hyun A. Lee ◽

...

Keyword(s):

Modelling And Simulation ◽

Pharmacokinetic Modelling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based Pharmacokinetic Modelling ◽

Virtual Population ◽

Physiologically Based

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Physiologically-based pharmacokinetic modelling of immune, reproductive and carcinogenic effects from contaminant exposure in polar bears (Ursus maritimus) across the Arctic

Environmental Research ◽

10.1016/j.envres.2015.03.011 ◽

2015 ◽

Vol 140 ◽

pp. 45-55 ◽

Author(s):

Rune Dietz ◽

Kim Gustavson ◽

Christian Sonne ◽

Jean-Pierre Desforges ◽

Frank F. Rigét ◽

...

Keyword(s):

Ursus Maritimus ◽

Polar Bears ◽

Pharmacokinetic Modelling ◽

Contaminant Exposure ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based Pharmacokinetic Modelling ◽

Physiologically Based ◽

Carcinogenic Effects

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Physiologically Based Pharmacokinetic Modelling to Identify Pharmacokinetic Parameters Driving Drug Exposure Changes in the Elderly

Clinical Pharmacokinetics ◽

10.1007/s40262-019-00822-9 ◽

2019 ◽

Vol 59 (3) ◽

pp. 383-401 ◽

Author(s):

Felix Stader ◽

Hannah Kinvig ◽

Melissa A. Penny ◽

Manuel Battegay ◽

Marco Siccardi ◽

...

Keyword(s):

Drug Exposure ◽

The Elderly ◽

Pharmacokinetic Parameters ◽

Pharmacokinetic Modelling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based Pharmacokinetic Modelling ◽

Physiologically Based

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Assessing pharmacokinetic differences in Caucasian and East Asian (Japanese, Chinese and Korean) populations driven by CYP2C19 polymorphism using physiologically-based pharmacokinetic modelling

European Journal of Pharmaceutical Sciences ◽

10.1016/j.ejps.2019.105061 ◽

2019 ◽

Vol 139 ◽

pp. 105061 ◽

Author(s):

Li Zhou ◽

Pradeep Sharma ◽

Karen Rowland Yeo ◽

Mitsuo Higashimori ◽

Hongmei Xu ◽

...

Keyword(s):

Pharmacokinetic Modelling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based Pharmacokinetic Modelling ◽

Cyp2c19 Polymorphism ◽

Physiologically Based

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