Incorporating patient preferences into drug development and regulatory decision making: Results from a quantitative pilot study with cancer patients, carers, and regulators

2016 ◽  
Vol 99 (5) ◽  
pp. 548-554 ◽  
Author(s):  
D Postmus ◽  
M Mavris ◽  
HL Hillege ◽  
T Salmonson ◽  
B Ryll ◽  
...  
Keyword(s):  
Decision Making ◽  
Pilot Study ◽  
Drug Development ◽  
Cancer Patients ◽  
Patient Preferences ◽  
Regulatory Decision

Patient preferences regarding medical decision making in the emergency care setting: a pilot-study

2015 ◽  
Vol 33 (5) ◽  
pp. 719-721 ◽  
Author(s):  
Daniel J. Reschke ◽  
Zachary H. Seeskin ◽  
Elizabeth A. Hahn ◽  
Peter S. Pang
Keyword(s):  
Decision Making ◽  
Pilot Study ◽  
Emergency Care ◽  
Patient Preferences ◽  
Medical Decision Making ◽  
Care Setting ◽  
Medical Decision

scholarly journals Physiologically Based Pharmacokinetics Is Impacting Drug Development and Regulatory Decision Making

2015 ◽  
Vol 4 (6) ◽  
pp. 313-315 ◽  
Author(s):  
M Rowland ◽  
LJ Lesko ◽  
A Rostami-Hodjegan
Keyword(s):  
Decision Making ◽  
Drug Development ◽  
Physiologically Based Pharmacokinetics ◽  
Regulatory Decision ◽  
Physiologically Based

scholarly journals A Challenge for Clinical Pharmacologists: How Can We Measure Scientific Impact of Publications in Drug Development and in Regulatory Decision Making?

2018 ◽  
Vol 105 (5) ◽  
pp. 1071-1073
Author(s):  
Virginia D. Schmith ◽  
Kellie Schoolar Reynolds ◽  
Kim L.R. Brouwer ◽  
Paolo Vicini
Keyword(s):  
Decision Making ◽  
Drug Development ◽  
Scientific Impact ◽  
Regulatory Decision

Patient opinions and preferences in drug development and regulatory decision making

2011 ◽  
Vol 8 (1) ◽  
pp. e11-e14 ◽  
Author(s):  
Alasdair Breckenridge
Keyword(s):  
Decision Making ◽  
Drug Development ◽  
Regulatory Decision

scholarly journals The SAKK cancer-specific geriatric assessment (C-SGA): a pilot study of a brieftool for clinical decision-making in older cancer patients

2013 ◽  
Vol 13 (1) ◽  
Author(s):  
Kerri M Clough-Gorr ◽  
Lea Noti ◽  
Peter Brauchli ◽  
Richard Cathomas ◽  
Marius R Fried ◽  
...  
Keyword(s):  
Decision Making ◽  
Pilot Study ◽  
Cancer Patients ◽  
Geriatric Assessment ◽  
Clinical Decision Making ◽  
Clinical Decision ◽  
Older Cancer Patients

Pharmacogenomics in Drug Development and Regulatory Decision-making: the Genomic Data Submission (GDS) Proposal

2004 ◽  
Vol 5 (1) ◽  
pp. 25-30 ◽  
Author(s):  
Ronald A Salerno ◽  
Lawrence J Lesko
Keyword(s):  
Decision Making ◽  
Drug Development ◽  
Genomic Data ◽  
Data Submission ◽  
Regulatory Decision

The physician–patient relationship in treatment decision making at the end of life: A pilot study of cancer patients in a Southeast Asian society

2012 ◽  
Vol 11 (1) ◽  
pp. 13-19 ◽  
Author(s):  
Zheng Jie Marc Ho ◽  
Lalit Kumar Radha Krishna ◽  
Cynthia Goh ◽  
Chung Pheng Alethea Yee
Keyword(s):  
Decision Making ◽  
Pilot Study ◽  
Cancer Patients ◽  
Care Service ◽  
Symptom Control ◽  
Palliative Care Service ◽  
Southeast Asian ◽  
Singapore General Hospital ◽  
Asian Society ◽  
Physician Patient

AbstractBackground:The traditional relationship between patient and physician in East Asian society has often been described as “paternalistic.” However, in an increasingly Westernized world, our knowledge of how patients perceive the role of the physician in their decision making regarding treatment is lacking.Objective:This article is part of a larger pilot study exploring the patient–physician dynamic on decision making among Southeast Asian palliative cancer patients. We explore: (1) influence of physicians, (2) the effect of symptom control and quality of life, and (3) dynamics and communication of physicians.Design:An interviewer-administered questionnaire was distributed, with 18 questions related to physician–patient interactions asked. Most questions followed a three point scale: “agree,” “neutral,” and “disagree,” and spontaneous answers beyond this framework were recorded.Setting/Participants:Thirty patients from the palliative care service were interviewed, including inpatients at Singapore General Hospital and those attending outpatient clinics at the National Cancer Centre.Results:Patients said that they themselves and their physicians were the main influences (80% each), over family members (48.3%). Some patients (26.7%) felt that symptoms were not well controlled, and 42.9% identified low mood or anxiety. Some patients (44.8%) felt that their condition had an effect on decision making. Most patients (89.3%) had a good relationship with the staff, with >80% being comfortable with discussions held. However, 20.7% of patients felt dissatisfied with the information provided, and 62.1% of patients wanted full disclosure of information.Significance of results:Patients appeared to place highest regard in both autonomy and physician input in making decisions, accompanied by an increased desire for more information. These reflect deviation away from traditional thinking of paternalistic doctoring in East Asia.

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