Ibrutinib Dosing Strategies Based on Interaction Potential of CYP3A4 Perpetrators Using Physiologically Based Pharmacokinetic Modeling

L de Zwart; J Snoeys; J De Jong; J Sukbuntherng; E Mannaert; M Monshouwer

doi:10.1002/cpt.419

Ibrutinib Dosing Strategies Based on Interaction Potential of CYP3A4 Perpetrators Using Physiologically Based Pharmacokinetic Modeling

Clinical Pharmacology & Therapeutics ◽

10.1002/cpt.419 ◽

2016 ◽

Vol 100 (5) ◽

pp. 548-557 ◽

Cited By ~ 50

Author(s):

L de Zwart ◽

J Snoeys ◽

J De Jong ◽

J Sukbuntherng ◽

E Mannaert ◽

...

Keyword(s):

Interaction Potential ◽

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

Dosing Strategies

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Evaluation of the Drug–Drug Interaction Potential of Acalabrutinib and Its Active Metabolite, ACP ‐5862, Using a Physiologically‐Based Pharmacokinetic Modeling Approach

CPT Pharmacometrics & Systems Pharmacology ◽

10.1002/psp4.12408 ◽

2019 ◽

Vol 8 (7) ◽

pp. 489-499 ◽

Cited By ~ 1

Author(s):

Diansong Zhou ◽

Terry Podoll ◽

Yan Xu ◽

Ganesh Moorthy ◽

Karthick Vishwanathan ◽

...

Keyword(s):

Drug Interaction ◽

Interaction Potential ◽

Active Metabolite ◽

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Modeling Approach ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

Drug Drug Interaction

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Evaluation of Cytochrome P450 3A4-Mediated Drug–Drug Interaction Potential for Cobimetinib Using Physiologically Based Pharmacokinetic Modeling and Simulation

Clinical Pharmacokinetics ◽

10.1007/s40262-016-0412-5 ◽

2016 ◽

Vol 55 (11) ◽

pp. 1435-1445 ◽

Cited By ~ 16

Author(s):

Nageshwar R. Budha ◽

Tao Ji ◽

Luna Musib ◽

Steve Eppler ◽

Mark Dresser ◽

...

Keyword(s):

Cytochrome P450 ◽

Drug Interaction ◽

Modeling And Simulation ◽

Interaction Potential ◽

Pharmacokinetic Modeling ◽

Cytochrome P450 3A4 ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

Drug Drug Interaction

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Simulation and Prediction of the Drug‐Drug Interaction Potential of Naloxegol by Physiologically Based Pharmacokinetic Modeling

CPT Pharmacometrics & Systems Pharmacology ◽

10.1002/psp4.12070 ◽

2016 ◽

Vol 5 (5) ◽

pp. 250-257 ◽

Cited By ~ 22

Author(s):

D Zhou ◽

K Bui ◽

M Sostek ◽

N Al‐Huniti

Keyword(s):

Drug Interaction ◽

Interaction Potential ◽

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

Drug Drug Interaction

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Applications of Physiologically Based Pharmacokinetic Modeling of Rivaroxaban—Renal and Hepatic Impairment and Drug‐Drug Interaction Potential

The Journal of Clinical Pharmacology ◽

10.1002/jcph.1784 ◽

2021 ◽

Author(s):

Stefan Willmann ◽

Katrin Coboeken ◽

Stefanie Kapsa ◽

Kirstin Thelen ◽

Markus Mundhenke ◽

...

Keyword(s):

Drug Interaction ◽

Interaction Potential ◽

Hepatic Impairment ◽

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

Drug Drug Interaction

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Prediction of drug–drug interaction potential using physiologically based pharmacokinetic modeling

Archives of Pharmacal Research ◽

10.1007/s12272-017-0976-0 ◽

2017 ◽

Vol 40 (12) ◽

pp. 1356-1379 ◽

Cited By ~ 18

Author(s):

Jee Sun Min ◽

Soo Kyung Bae

Keyword(s):

Drug Interaction ◽

Interaction Potential ◽

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

Drug Drug Interaction

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Assessment of cytochrome P450-mediated drug-drug interaction potential of orteronel and exposure changes in patients with renal impairment using physiologically based pharmacokinetic modeling and simulation

Biopharmaceutics & Drug Disposition ◽

10.1002/bdd.1919 ◽

2014 ◽

Vol 35 (9) ◽

pp. 543-552 ◽

Cited By ~ 19

Author(s):

Chuang Lu ◽

Ajit Suri ◽

Wen Chyi Shyu ◽

Shimoga Prakash

Keyword(s):

Cytochrome P450 ◽

Drug Interaction ◽

Renal Impairment ◽

Modeling And Simulation ◽

Interaction Potential ◽

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

Drug Drug Interaction

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Physiologically-based pharmacokinetic modeling of different size polyethylene glycol-coated gold nanoparticles in mice

10.1615/ihtc16.nmt.023362 ◽

2018 ◽

Author(s):

Linjing Deng ◽

Jinping Zhao ◽

Yufeng Miao ◽

Xu Hu ◽

Qihong Deng

Keyword(s):

Gold Nanoparticles ◽

Polyethylene Glycol ◽

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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Physiologically-Based Pharmacokinetic Modeling to Predict Changes in Drug Exposure during Pregnancy Using the Simcyp Simulator

10.26226/morressier.57d6b2b7d462b8028d88e945 ◽

2016 ◽

Author(s):

Suvarchala Kiranmai Avvari

Keyword(s):

Drug Exposure ◽

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

Exposure During Pregnancy

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Physiologically‐Based Pharmacokinetic Modeling of Atorvastatin Incorporating Delayed Gastric Emptying and Acid‐to‐Lactone Conversion

CPT Pharmacometrics & Systems Pharmacology ◽

10.1002/psp4.12447 ◽

2019 ◽

Vol 8 (9) ◽

pp. 664-675 ◽

Cited By ~ 5

Author(s):

Bridget L. Morse ◽

Jeffrey J. Alberts ◽

Maria M. Posada ◽

Jessica Rehmel ◽

Anil Kolur ◽

...

Keyword(s):

Gastric Emptying ◽

Delayed Gastric Emptying ◽

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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Preliminary physiologically based pharmacokinetic modeling of renally cleared drugs in Chinese pregnant women

Biopharmaceutics & Drug Disposition ◽

10.1002/bdd.2243 ◽

2020 ◽

Vol 41 (6) ◽

pp. 248-267 ◽

Cited By ~ 1

Author(s):

Ling Song ◽

Zhiheng Yu ◽

Yifan Xu ◽

Xiaobei Li ◽

Xuanlin Liu ◽

...

Keyword(s):

Pregnant Women ◽

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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