Physiologically-Based Pharmacokinetic Modeling to Predict Changes in Drug Exposure during Pregnancy Using the Simcyp Simulator

Physiologically Based ◽

Exposure During Pregnancy

Application of Physiologically Based Pharmacokinetic Modeling to Predict Drug Exposure and Support Dosing Recommendations for Potential Drug‐Drug Interactions or in Special Populations: An Example Using Tofacitinib

The Journal of Clinical Pharmacology ◽

10.1002/jcph.1679 ◽

2020 ◽

Vol 60 (12) ◽

pp. 1617-1628

Author(s):

Susanna Tse ◽

Martin E. Dowty ◽

Sujatha Menon ◽

Pankaj Gupta ◽

Sriram Krishnaswami

Keyword(s):

Drug Interactions ◽

Drug Exposure ◽

Special Populations ◽

Potential Drug ◽

Physiologically Based Pharmacokinetic Modeling to Identify Physiological and Molecular Characteristics Driving Variability in Drug Exposure

Clinical Pharmacology & Therapeutics ◽

10.1002/cpt.1076 ◽

2018 ◽

Vol 104 (6) ◽

pp. 1219-1228 ◽

Cited By ~ 11

Author(s):

Andrew Rowland ◽

Madelé van Dyk ◽

Ashley M. Hopkins ◽

Reham Mounzer ◽

Thomas M. Polasek ◽

...

Keyword(s):

Drug Exposure ◽

Molecular Characteristics ◽

Evaluation of Maternal Drug Exposure Following the Administration of Antenatal Corticosteroids During Late Pregnancy Using Physiologically‐Based Pharmacokinetic Modeling

Clinical Pharmacology & Therapeutics ◽

10.1002/cpt.1438 ◽

2019 ◽

Vol 106 (1) ◽

pp. 164-173 ◽

Cited By ~ 10

Author(s):

Alice Ban Ke ◽

Mark A. Milad

Keyword(s):

Drug Exposure ◽

Late Pregnancy ◽

Antenatal Corticosteroids ◽

The Future of Physiologically Based Pharmacokinetic Modeling to Predict Drug Exposure in Pregnant Women

CPT Pharmacometrics & Systems Pharmacology ◽

10.1038/psp.2013.9 ◽

2013 ◽

Vol 2 (3) ◽

pp. 33 ◽

Cited By ~ 7

Author(s):

AA Vinks

Keyword(s):

Pregnant Women ◽

Drug Exposure ◽

Physiologically Based ◽

The Future

Physiologically-based pharmacokinetic modeling of different size polyethylene glycol-coated gold nanoparticles in mice

10.1615/ihtc16.nmt.023362 ◽

2018 ◽

Author(s):

Linjing Deng ◽

Jinping Zhao ◽

Yufeng Miao ◽

Xu Hu ◽

Qihong Deng

Keyword(s):

Gold Nanoparticles ◽

Polyethylene Glycol ◽

Physiologically‐Based Pharmacokinetic Modeling of Atorvastatin Incorporating Delayed Gastric Emptying and Acid‐to‐Lactone Conversion

CPT Pharmacometrics & Systems Pharmacology ◽

10.1002/psp4.12447 ◽

2019 ◽

Vol 8 (9) ◽

pp. 664-675 ◽

Cited By ~ 5

Author(s):

Bridget L. Morse ◽

Jeffrey J. Alberts ◽

Maria M. Posada ◽

Jessica Rehmel ◽

Anil Kolur ◽

...

Keyword(s):

Gastric Emptying ◽

Delayed Gastric Emptying ◽

Preliminary physiologically based pharmacokinetic modeling of renally cleared drugs in Chinese pregnant women

Biopharmaceutics & Drug Disposition ◽

10.1002/bdd.2243 ◽

2020 ◽

Vol 41 (6) ◽

pp. 248-267 ◽

Cited By ~ 1

Author(s):

Ling Song ◽

Zhiheng Yu ◽

Yifan Xu ◽

Xiaobei Li ◽

Xuanlin Liu ◽

...

Keyword(s):

Pregnant Women ◽

Prediction of fluoxetine and norfluoxetine pharmacokinetic profiles using physiologically based pharmacokinetic modeling

The Journal of Clinical Pharmacology ◽

10.1002/jcph.1927 ◽

2021 ◽

Author(s):

Hyeon‐Cheol Jeong ◽

Yoon‐Jee Chae ◽

Sooyeun Lee ◽

Wonku Kang ◽

Hwi‐yeol Yun ◽

...

Keyword(s):

Pharmacokinetic Profiles ◽

Physiologically Based Pharmacokinetic Modeling Approach to Predict Drug‐Drug Interactions With Ethionamide Involving Impact of Genetic Polymorphism on FMO3

The Journal of Clinical Pharmacology ◽

10.1002/jcph.1378 ◽

2019 ◽

Vol 59 (6) ◽

pp. 880-889 ◽

Cited By ~ 1

Author(s):

Phuong Thi Thu Nguyen ◽

Md Masud Parvez ◽

Min Jung Kim ◽

Sung Eun Yoo ◽

Sangzin Ahn ◽

...

Keyword(s):

Genetic Polymorphism ◽

Drug Interactions ◽

Modeling Approach ◽

Physiologically Based Pharmacokinetic Modeling and Tissue Distribution Characteristics of SHetA2 in Tumor-Bearing Mice

The AAPS Journal ◽

10.1208/s12248-020-0421-z ◽

2020 ◽

Vol 22 (2) ◽

Author(s):

Ankur Sharma ◽

Mengjie Li ◽

Elangovan Thavathiru ◽

Mariam Ibrahim ◽

Lucila Garcia-Contreras ◽

...

Keyword(s):

Tissue Distribution ◽

Distribution Characteristics ◽

Tumor Bearing ◽