scholarly journals Metabolic correlates of prevalent mild cognitive impairment and Alzheimer's disease in adults with Down syndrome

2020 ◽  
Vol 12 (1) ◽  
Author(s):  
Mark Mapstone ◽  
Thomas J Gross ◽  
Fabio Macciardi ◽  
Amrita K Cheema ◽  
Melissa Petersen ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Down Syndrome ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment

scholarly journals Proteomic profiles of prevalent mild cognitive impairment and Alzheimer's disease among adults with Down syndrome

2020 ◽  
Vol 12 (1) ◽  
Author(s):  
Melissa Petersen ◽  
Fan Zhang ◽  
Sharon J. Krinsky‐McHale ◽  
Wayne Silverman ◽  
Joseph H. Lee ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Down Syndrome ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment

P2-440: MEG CHARACTERIZATION OF ALZHEIMER'S DISEASE AND MILD COGNITIVE IMPAIRMENT IN PEOPLE WITH DOWN SYNDROME

2006 ◽  
Vol 14 (7S_Part_16) ◽  
pp. P884-P884
Author(s):  
Federico Ramirez Toraño ◽  
Javier García Alba ◽  
Ricardo Bruña Fernández
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Down Syndrome ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment

Neuropsychological and neurophysiological characterization of mild cognitive impairment and Alzheimer's disease in Down syndrome

2019 ◽  
Vol 84 ◽  
pp. 70-79 ◽  
Author(s):  
Javier García-Alba ◽  
Federico Ramírez-Toraño ◽  
Susanna Esteba-Castillo ◽  
Ricardo Bruña ◽  
Fernando Moldenhauer ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Down Syndrome ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment

scholarly journals Proteomic profiles of incident mild cognitive impairment and Alzheimer's disease among adults with Down syndrome

2020 ◽  
Vol 12 (1) ◽  
Author(s):  
Sid E. O'Bryant ◽  
Fan Zhang ◽  
Wayne Silverman ◽  
Joseph H. Lee ◽  
Sharon J. Krinsky‐McHale ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Down Syndrome ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment

Selective Attention Deficits Associated With Mild Cognitive Impairment and Early Stage Alzheimer's Disease in Adults With Down Syndrome

2008 ◽  
Vol 113 (5) ◽  
pp. 369-386 ◽  
Author(s):  
Sharon J. Krinsky-McHale ◽  
Darlynne A. Devenny ◽  
Phyllis Kittler ◽  
Wayne Silverman
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Down Syndrome ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Early Stage ◽  
Good Sensitivity ◽  
Neuropsychological Battery ◽  
Selective Attention Deficits ◽  
Healthy Participants

Abstract Adults with Down syndrome and early stage Alzheimer's disease showed decline in their ability to selectively attend to stimuli in a multitrial cancellation task. They also showed variability in their performance over the test trials, whereas healthy participants showed stability. These changes in performance were observed approximately 2 years prior to a physician's diagnosis of possible Alzheimer's disease, which was made when they were exhibiting declines in episodic memory suggestive of mild cognitive impairment. Performance on this task varied with the evolution of dementia, showed modestly good sensitivity and specificity, and was relatively easy to administer. Given these qualities this task could be a valuable addition to a neuropsychological battery intended for the assessment of mild cognitive impairment and Alzheimer's disease in adults with Down syndrome.

Hypersynchronized MEG brain networks in patients with mild cognitive impairment and Alzheimer's disease in Down syndrome

2021 ◽  
Author(s):  
Federico Ramírez Toraño ◽  
Javier García Alba ◽  
Ricardo Bruña ◽  
Susanna Esteba Castillo ◽  
Lucía Vaquero ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Down Syndrome ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Brain Networks
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