Cycloaddition versus Alkylation Reactions of 2-Vinylindoles with α,β-Unsaturated Carbonyl Compounds Under Gold Catalysis

2013 ◽  
Vol 2013 (28) ◽  
pp. 6267-6279 ◽  
Author(s):  
Valentina Pirovano ◽  
Monica Dell'Acqua ◽  
Diego Facoetti ◽  
Donatella Nava ◽  
Silvia Rizzato ◽  
...  
Keyword(s):  
Carbonyl Compounds ◽  
Gold Catalysis ◽  
Alkylation Reactions

Cycloaddition versus Alkylation Reactions of 2-Vinylindoles with α,β-Unsaturated Carbonyl Compounds Under Gold Catalysis (Eur. J. Org. Chem. 28/2013)

2013 ◽  
Vol 2013 (28) ◽  
pp. n/a-n/a
Author(s):  
Valentina Pirovano ◽  
Monica Dell'Acqua ◽  
Diego Facoetti ◽  
Donatella Nava ◽  
Silvia Rizzato ◽  
...  
Keyword(s):  
Carbonyl Compounds ◽  
Gold Catalysis ◽  
Alkylation Reactions

ChemInform Abstract: Cycloaddition versus Alkylation Reactions of 2-Vinylindoles with α,β-Unsaturated Carbonyl Compounds under Gold Catalysis.

ChemInform ◽  
2014 ◽  
Vol 45 (11) ◽  
pp. no-no
Author(s):  
Valentina Pirovano ◽  
Monica Dell'Acqua ◽  
Diego Facoetti ◽  
Donatella Nava ◽  
Silvia Rizzato ◽  
...  
Keyword(s):  
Carbonyl Compounds ◽  
Gold Catalysis ◽  
Alkylation Reactions

Synthesis of 4-hydrazinopyrazolo[3,4-d]pyrimidines and their Reactions with Carbonyl Compounds

2013 ◽  
Vol 37 (1) ◽  
pp. 6-10 ◽  
Author(s):  
Mastoura M. Edrees
Keyword(s):  
Hydrazine Hydrate ◽  
Carbonyl Compounds ◽  
Pyrazole Derivatives ◽  
Pyrimidine Derivatives ◽  
Pyrazolone Derivatives ◽  
Alkylation Reactions

Synthesis of a new 4-hydrazinopyrazolo[3,4- d]pyrimidine was achieved via heating (4,6-dithioxo-1 H-pyrazolo[3,4- d] pyrimidin-3-yl)acetonitrile with hydrazine hydrate. Reactions of the latter product with thiophene-2-carbaldehyde and ethyl hydrazonoacetoacetate analogues afforded the corresponding hydrazone and pyrazole derivatives, respectively. Similarly, condensation of 2-[6-(benzylsulfanyl)-4-hydrazino-1 H-pyrazolo[3,4- d]pyrimidin-3-yl]acetonitrile with thiophene-2-carbaldehyde and ethyl hydrazonoacetoacetate analogues gave the respective hydrazone and pyrazolone derivatives. Alkylation reactions of 2-[4,6-bis(benzylsulfanyl)-1 H-pyrazolo[3,4- d]pyrimidin-3-yl]acetonitrile with arylamines gave the respective 4-( N-arylamino)-6-benzylsulfanylpyrazolo[3,4- d]pyrimidine derivatives.

ChemInform Abstract: N-Substituted Ephedrines as Chiral Auxiliaries in Enantioselective Alkylation Reactions of Carbonyl Compounds

ChemInform ◽  
2016 ◽  
Vol 47 (15) ◽  
pp. no-no
Author(s):  
Alejandro Cruz ◽  
Itzia Irene Padilla-Martinez ◽  
Maria Esther Bautista-Ramirez
Keyword(s):  
Carbonyl Compounds ◽  
Chiral Auxiliaries ◽  
Enantioselective Alkylation ◽  
Alkylation Reactions

Silicon Assisted Sulfuration: Tetrachlorosilane-Sodium Sulfide-A New Potent Thionating Reagent for Carbonyl Compounds

2007 ◽  
Author(s):  
T. A. Salama ◽  
S. S. Elmorsy ◽  
A. M. Khalil ◽  
M. A. Ismail ◽  
A. S. El-Ahl
Keyword(s):  
Carbonyl Compounds ◽  
Sodium Sulfide

A FACILE SYNTHESIS AND REACTIONS OF AMINO SELENOLO[2,3-b]PYRIDINE CARBOXYLATE

2015 ◽  
Vol 12 (1) ◽  
pp. 3910-3918 ◽  
Author(s):  
Dr Remon M Zaki ◽  
Prof Adel M. Kamal El-Dean ◽  
Dr Nermin A Marzouk ◽  
Prof Jehan A Micky ◽  
Mrs Rasha H Ahmed
Keyword(s):  
Biological Activity ◽  
Carbonyl Compounds ◽  
Mass Spectra ◽  
The Other ◽  
Pyridine Derivatives ◽  
Facile Synthesis ◽  
High Biological Activity ◽  
Basic Hydrolysis ◽  
Pyridine Carboxylate ◽  
Hydrolysis Of

 Incorporating selenium metal bonded to the pyridine nucleus was achieved by the reaction of selenium metal with 2-chloropyridine carbonitrile 1 in the presence of sodium borohydride as reducing agent. The resulting non isolated selanyl sodium salt was subjected to react with various α-halogenated carbonyl compounds to afford the selenyl pyridine derivatives 3a-f  which compounds 3a-d underwent Thorpe-Ziegler cyclization to give 1-amino-2-substitutedselenolo[2,3-b]pyridine compounds 4a-d, while the other compounds 3e,f failed to be cyclized. Basic hydrolysis of amino selenolo[2,3-b]pyridine carboxylate 4a followed by decarboxylation furnished the corresponding amino selenolopyridine compound 6 which was used as a versatile precursor for synthesis of other heterocyclic compound 7-16. All the newly synthesized compounds were established by elemental and spectral analysis (IR, 1H NMR) in addition to mass spectra for some of them hoping these compounds afforded high biological activity.

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