Müller glial cell reactivation in Xenopus models of retinal degeneration

Glia ◽  
2017 ◽  
Vol 65 (8) ◽  
pp. 1333-1349 ◽  
Author(s):  
Rahul Langhe ◽  
Albert Chesneau ◽  
Gabriele Colozza ◽  
Magdalena Hidalgo ◽  
Divya Ail ◽  
...  
Keyword(s):  
Retinal Degeneration ◽  
Glial Cell ◽  
Cell Reactivation ◽  
Müller Glial Cell

scholarly journals MIO-M1 Cells and Similar Müller Glial Cell Lines Derived from Adult Human Retina Exhibit Neural Stem Cell Characteristics

Stem Cells ◽  
2007 ◽  
Vol 25 (8) ◽  
pp. 2033-2043 ◽  
Author(s):  
Jean M. Lawrence ◽  
Shweta Singhal ◽  
Bhairavi Bhatia ◽  
David J. Keegan ◽  
Thomas A. Reh ◽  
...  
Keyword(s):  
Stem Cell ◽  
Glial Cell ◽  
Neural Stem Cell ◽  
Cell Lines ◽  
Human Retina ◽  
Adult Human ◽  
Müller Glial Cell

scholarly journals Characterization of a Spontaneously Immortalized Murine Müller Glial Cell Line QMMuC-1

2018 ◽  
Vol 59 (3) ◽  
pp. 1666 ◽  
Author(s):  
Josy Augustine ◽  
Sofia Pavlou ◽  
Michael O'Hare ◽  
Kevin Harkin ◽  
Alan Stitt ◽  
...  
Keyword(s):  
Cell Line ◽  
Glial Cell ◽  
Müller Glial Cell

scholarly journals Single-Cell RNA Sequencing in Human Retinal Degeneration Reveals Distinct Glial Cell Populations

Cells ◽  
2020 ◽  
Vol 9 (2) ◽  
pp. 438 ◽  
Author(s):  
Andrew P. Voigt ◽  
Elaine Binkley ◽  
Miles J. Flamme-Wiese ◽  
Shemin Zeng ◽  
Adam P. DeLuca ◽  
...  
Keyword(s):  
Single Cell ◽  
Retinal Degeneration ◽  
Rna Sequencing ◽  
Glial Cell ◽  
Glial Cells ◽  
Peripheral Retina ◽  
Cell Populations ◽  
Specific Gene ◽  
Autoimmune Retinopathy ◽  
Single Cell Rna Sequencing

Degenerative diseases affecting retinal photoreceptor cells have numerous etiologies and clinical presentations. We clinically and molecularly studied the retina of a 70-year-old patient with retinal degeneration attributed to autoimmune retinopathy. The patient was followed for 19 years for progressive peripheral visual field loss and pigmentary changes. Single-cell RNA sequencing was performed on foveal and peripheral retina from this patient and four control patients, and cell-specific gene expression differences were identified between healthy and degenerating retina. Distinct populations of glial cells, including astrocytes and Müller cells, were identified in the tissue from the retinal degeneration patient. The glial cell populations demonstrated an expression profile consistent with reactive gliosis. This report provides evidence that glial cells have a distinct transcriptome in the setting of human retinal degeneration and represents a complementary clinical and molecular investigation of a case of progressive retinal disease.

Vanadium inhalation induces retinal Müller glial cell (MGC) alterations in a murine model

2017 ◽  
Vol 37 (2) ◽  
pp. 200-206 ◽  
Author(s):  
Silvana Cervantes-Yépez ◽  
Lorena Sofía López-Zepeda ◽  
Teresa I. Fortoul
Keyword(s):  
Glial Cell ◽  
Murine Model ◽  
Müller Glial Cell

scholarly journals Müller glial cell‐dependent regeneration of the neural retina: An overview across vertebrate model systems

2016 ◽  
Vol 245 (7) ◽  
pp. 727-738 ◽  
Author(s):  
Annaïg Hamon ◽  
Jérôme E. Roger ◽  
Xian‐Jie Yang ◽  
Muriel Perron
Keyword(s):  
Glial Cell ◽  
Neural Retina ◽  
Model Systems ◽  
Müller Glial Cell ◽  
Vertebrate Model

scholarly journals MAPK signaling during Müller glial cell development in retina explant cultures

2010 ◽  
Vol 3 (4) ◽  
pp. 129-133 ◽  
Author(s):  
Samuel Shao-Min Zhang ◽  
Hong Li ◽  
Ping Huang ◽  
Lucy Xi Lou ◽  
Xin-Yuan Fu ◽  
...  
Keyword(s):  
Glial Cell ◽  
Mapk Signaling ◽  
Cell Development ◽  
Müller Glial Cell ◽  
Explant Cultures

scholarly journals Müller Glial Cell-Provided Cellular Light Guidance through the Vital Guinea-Pig Retina

2011 ◽  
Vol 101 (11) ◽  
pp. 2611-2619 ◽  
Author(s):  
Silke Agte ◽  
Stephan Junek ◽  
Sabrina Matthias ◽  
Elke Ulbricht ◽  
Ines Erdmann ◽  
...  
Keyword(s):  
Guinea Pig ◽  
Glial Cell ◽  
Müller Glial Cell ◽  
Light Guidance

Potential role of glial cell line-derived neurotrophic factor receptors in Müller glial cells during light-induced retinal degeneration

Neuroscience ◽  
2003 ◽  
Vol 122 (1) ◽  
pp. 229-235 ◽  
Author(s):  
C Harada ◽  
T Harada ◽  
H.-M.A Quah ◽  
F Maekawa ◽  
K Yoshida ◽  
...  
Keyword(s):  
Retinal Degeneration ◽  
Cell Line ◽  
Glial Cell ◽  
Glial Cells ◽  
Neurotrophic Factor ◽  
Potential Role ◽  
Müller Glial Cells
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