This chapter focuses upon the needs of two approaches, economic evaluations based on decision analytic models, and those alongside clinical trials in terms of the collection and analysis of health state values. The first section of the chapter presents requirements that are likely to be common to any study in which health state values are collected from patients and/or members of the general population, including: who to ask, mode of administration, timing of assessments, sample size, and handling uncertainty. The second section of the chapter considers issues specific to trial-based economic evaluations, and the final section considers issues specific to the design and analysis of health state valuation data for economic models.
What is it going to be, TTO or SG? A direct test of the validity of health state valuation