scholarly journals A rare der(10)t(X;10)(p11.2;p11.2) in an elderly patient with therapy‐related acute myelomonocytic leukemia

eJHaem ◽  
2021 ◽  
Author(s):  
Masahiro Manabe ◽  
Nao Tanizawa ◽  
Satoru Nanno ◽  
Yuuji Hagiwara ◽  
Reiko Asada ◽  
...  
Keyword(s):  
Elderly Patient ◽  
Acute Myelomonocytic Leukemia ◽  
Myelomonocytic Leukemia

Acute myelomonocytic leukemia with oral manifestations: report of case

1988 ◽  
Vol 117 (7) ◽  
pp. 835-837 ◽  
Author(s):  
Carole V. Brenneise ◽  
John S. Mattson ◽  
James R. Commers
Keyword(s):  
Oral Manifestations ◽  
Acute Myelomonocytic Leukemia ◽  
Myelomonocytic Leukemia

Production of granulocyte colony-stimulating factor by acute myelomonocytic leukemia cells

1988 ◽  
Vol 12 (9) ◽  
pp. 745-750 ◽  
Author(s):  
Naoki Shirafuji ◽  
Shigetaka Asano ◽  
Koji Kozai ◽  
Satoshi Takahashi ◽  
Satoru Matsuda ◽  
...  
Keyword(s):  
Leukemia Cells ◽  
Granulocyte Colony Stimulating Factor ◽  
Colony Stimulating Factor ◽  
Acute Myelomonocytic Leukemia ◽  
Myelomonocytic Leukemia ◽  
Stimulating Factor

Acute myelomonocytic leukemia secondary to synchronous carcinomas of the breast and lung, and to metachronous renal cell carcinoma

1997 ◽  
Vol 123 (11-12) ◽  
pp. 678-680 ◽  
Author(s):  
Claudia Pötzsch ◽  
Sebastian Fetscher ◽  
Roland Mertelsmann ◽  
M. Lübbert
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Acute Myelomonocytic Leukemia ◽  
Myelomonocytic Leukemia

Bilateral Adrenal Masses in a Patient in Remission From Acute Myelomonocytic Leukemia

2015 ◽  
Vol 349 (6) ◽  
pp. e6
Author(s):  
Shiue-Wei Lai ◽  
Tsu-Yi Chao ◽  
Yi-Ying Wu
Keyword(s):  
Acute Myelomonocytic Leukemia ◽  
Adrenal Masses ◽  
Myelomonocytic Leukemia

Acute Myelomonocytic Leukemia in Children

1979 ◽  
Vol 62 (3) ◽  
pp. 137-142 ◽  
Author(s):  
Y. Barak ◽  
A. Ma ◽  
N.A. Shore
Keyword(s):  
Acute Myelomonocytic Leukemia ◽  
Myelomonocytic Leukemia ◽  
Leukemia In Children

scholarly journals A unique pattern of central nervous system leukemia in acute myelomonocytic leukemia associated with inv(16)(p13q22)

Blood ◽  
1985 ◽  
Vol 65 (5) ◽  
pp. 1071-1078
Author(s):  
R Holmes ◽  
MJ Keating ◽  
A Cork ◽  
Y Broach ◽  
J Trujillo ◽  
...  
Keyword(s):  
Median Duration ◽  
Myeloid Leukemia ◽  
Chromosome Analysis ◽  
Leptomeningeal Disease ◽  
Brain Scan ◽  
Fab Classification ◽  
Additional Chromosome ◽  
Acute Myelomonocytic Leukemia ◽  
Immature Cells ◽  
Myelomonocytic Leukemia

Twenty-six patients with inv(16)(p13q22) or del(16)(q22) in association with acute myelomonocytic leukemia (AMML-M4, FAB classification), and abnormal marrow eosinophils have been treated at this institute. Initial bone marrow eosinophilia (greater than or equal to 4%) was observed in 22 of 26 patients (85%), and abnormal eosinophil morphology, characterized by immature cells with some interspersed basophilic granules, was evident in 26 of 26 (100%). Giemsa-banded chromosome analysis performed in all patients revealed 16 cases with inv(16)(p13q22) alone, and ten cases with additional chromosome changes. Twenty-five patients received combination induction chemotherapy, and 23 (92%) achieved complete remission (CR). The median duration of remission was 18 months (range, six to 72 + months), and the median duration of survival was 34 months (range, 0.5 to 133 months). Nine patients (35%) relapsed in the CNS at a median time of 19 months (range, six to 133 months) from first marrow CR. All patients had leptomeningeal disease, and in addition, six of nine (66%) demonstrated two or more enhancing lesions on computed tomography brain scan, consistent with intracerebral myeloblastomas. Review of 384 Giemsa-banded patients with acute myeloid leukemia revealed no other morphologic or cytogenetic subgroup with either an equivalent incidence of CNS leukemia or documented intracerebral myeloblastomas. This series of inv(16)(p13q22)/del(16)(q22) AMML reports a favorable prognosis for such patients and associates a specific clonal cytogenetic subgroup of acute leukemia with a distinct propensity for CNS relapse, manifesting as leptomeningeal disease and intracerebral myeloblastomas.

scholarly journals Deletion of the long arm of chromosome 20 [del(20)(q11)] in myeloid disorders

Blood ◽  
1978 ◽  
Vol 52 (5) ◽  
pp. 868-877
Author(s):  
JR Testa ◽  
A Kinnealey ◽  
JD Rowley ◽  
DW Golde ◽  
D Potter
Keyword(s):  
Polycythemia Vera ◽  
Myeloproliferative Disorders ◽  
Cytotoxic Agents ◽  
Partial Deletion ◽  
Previous Therapy ◽  
Chromosome 20 ◽  
Acute Myelomonocytic Leukemia ◽  
Cytogenetic Analyses ◽  
Myelomonocytic Leukemia ◽  
Group Chromosome

Detailed clinical and cytogenetic studies were performed in five patients who had abnormal hematopoiesis and an acquired deletion of an F-group chromosome. Cytogenetic analyses, with banding techniques, of cells from bone marrow, spleen, or unstimulated peripheral blood showed a partial deletion of the long arm of one chromosome 20 [del(20)(q11)] in all five patients. Three patients had myeloproliferative disorders of uncertain classification, the fourth had possible preleukemia, and the fifth had acute myelomonocytic leukemia. Although the five cases showed certain similarities, the clinical and hematologic findings seen with the 20q- abnormality were not specific. None of the patients showed evidence of polycythemia vera or idiopathic acquired refractory sideroblastic anemia, two diseases previously associated with the 20q-. Our studies indicate that the 20q- abnormality is not limited to diseases primarily affecting erythropoiesis but that it can be found in the broader spectrum of myeloid disorders. In polycythemia vera, the 20q- has sometimes been regarded as a possible result of previous therapy with cytotoxic agents; however, four of our patients were untreated when the deletion was first noted.

A novel translocation, t(9;21)(q13;q22) rearranging the RUNX1 gene in acute myelomonocytic leukemia

2002 ◽  
Vol 45 (2) ◽  
pp. 67-69 ◽  
Author(s):  
Sylvie Paulien ◽  
Odile Maarek ◽  
Marie-Thérèse Daniel ◽  
Roland Berger
Keyword(s):  
Runx1 Gene ◽  
Acute Myelomonocytic Leukemia ◽  
Myelomonocytic Leukemia

scholarly journals Acute Myelomonocytic Leukemia in a Patient with Multiple Myeloma: Evidence for Different Clonal Origin.

1995 ◽  
Vol 34 (6) ◽  
pp. 546-549 ◽  
Author(s):  
Kazunori NAKASE ◽  
Kota TSUJI ◽  
Masaki HASEGAWA ◽  
Yoshinori SUZUKI ◽  
Shigehisa TAMAKI ◽  
...  
Keyword(s):  
Multiple Myeloma ◽  
Acute Myelomonocytic Leukemia ◽  
Clonal Origin ◽  
Myelomonocytic Leukemia
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