Vicarious nucleophilic substitution: a dramatically shortened synthesis of 2-amino-6-nitrobenzoic acid labelled with carbon-14

2011 ◽  
Vol 54 (7) ◽  
pp. 345-351
Author(s):  
Terence P. Kelly ◽  
Crist N. Filer ◽  
Christopher Wright
Synlett ◽  
2018 ◽  
Vol 29 (14) ◽  
pp. 1842-1846 ◽  
Author(s):  
Lamouri Hammal ◽  
Laurent El Kaïm ◽  
Samira Baaziz ◽  
Mansour Kerim ◽  
Marie Cordier

A two-step isoindolone synthesis has been achieved by using an Ugi/oxidative vicarious nucleophilic substitution sequence starting from 3-nitrobenzoic acid and aromatic aldehydes. Loss of the amido group was observed as well as a further oxidative process towards hydroxyisoindolone derivatives after prolonged stirring open to the atmosphere.


ChemInform ◽  
2010 ◽  
Vol 28 (23) ◽  
pp. no-no
Author(s):  
M. D. DREW ◽  
D. A. JACKSON ◽  
N. J. LAWRENCE ◽  
J. LIDDLE ◽  
R. G. PRITCHARD

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