Growth and cranial development in the Andean frogs of the genusTelmatobius(Anura: Telmatobiidae): Exploring the relation of heterochrony and skeletal diversity

2018 ◽  
Vol 279 (9) ◽  
pp. 1269-1281 ◽  
Author(s):  
J. Sebastián Barrionuevo
Keyword(s):  
Cranial Development ◽  
Skeletal Diversity

scholarly journals Frontispiece: Achieving Skeletal Diversity in Peptide Macrocycles through The Use of Heterocyclic Grafts

2018 ◽  
Vol 24 (28) ◽  
Author(s):  
Sherif J. Kaldas ◽  
Andrei K. Yudin
Keyword(s):  
Skeletal Diversity

scholarly journals Mammalian skull heterochrony reveals modular evolution and a link between cranial development and brain size

2014 ◽  
Vol 5 (1) ◽  
Author(s):  
Daisuke Koyabu ◽  
Ingmar Werneburg ◽  
Naoki Morimoto ◽  
Christoph P. E. Zollikofer ◽  
Analia M. Forasiepi ◽  
...  
Keyword(s):  
Brain Size ◽  
Cranial Development ◽  
Modular Evolution ◽  
Mammalian Skull

Skeletal Diversity via a Folding Pathway:  Synthesis of Indole Alkaloid-Like Skeletons

2005 ◽  
Vol 7 (1) ◽  
pp. 47-50 ◽  
Author(s):  
Hiroki Oguri ◽  
Stuart L. Schreiber
Keyword(s):  
Indole Alkaloid ◽  
Folding Pathway ◽  
Skeletal Diversity

Achieving Skeletal Diversity in Peptide Macrocycles through The Use of Heterocyclic Grafts

2018 ◽  
Vol 24 (28) ◽  
pp. 7074-7082 ◽  
Author(s):  
Sherif J. Kaldas ◽  
Andrei K. Yudin
Keyword(s):  
Skeletal Diversity

scholarly journals Divergent synthesis of complex diterpenes through a hybrid oxidative approach

Science ◽  
2020 ◽  
Vol 369 (6505) ◽  
pp. 799-806 ◽  
Author(s):  
Xiao Zhang ◽  
Emma King-Smith ◽  
Liao-Bin Dong ◽  
Li-Cheng Yang ◽  
Jeffrey D. Rudolf ◽  
...  
Keyword(s):  
Natural Products ◽  
De Novo ◽  
Biological Activities ◽  
Structural Complexity ◽  
Enzymatic Oxidation ◽  
Chemical Tools ◽  
Skeletal Rearrangements ◽  
Skeletal Diversity

Polycyclic diterpenes exhibit many important biological activities, but de novo synthetic access to these molecules is highly challenging because of their structural complexity. Semisynthetic access has also been limited by the lack of chemical tools for scaffold modifications. We report a chemoenzymatic platform to access highly oxidized diterpenes by a hybrid oxidative approach that strategically combines chemical and enzymatic oxidation methods. This approach allows for selective oxidations of previously inaccessible sites on the parent carbocycles and enables abiotic skeletal rearrangements to additional underlying architectures. We synthesized a total of nine complex natural products with rich oxygenation patterns and skeletal diversity in 10 steps or less from ent-steviol.

Concerning the Cranial Development in the Greenish Elaenia, Myiopagis viridicata (Vieillot)

1967 ◽  
Vol 78 (2) ◽  
pp. 529 ◽  
Author(s):  
Raymond McNeil
Keyword(s):  
Cranial Development

Subclassification of Anencephalic Human Fetuses According to Morphology of the Posterior Cranial Fossa

2004 ◽  
Vol 7 (6) ◽  
pp. 601-606 ◽  
Author(s):  
Jens Fog Lomholt ◽  
Birgit Fischer-Hansen ◽  
Jean W. Keeling ◽  
Ingermarie Reintoft ◽  
Inger Kjær
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Posterior Cranial Fossa ◽  
Cranial Morphology ◽  
Bony Tissue ◽  
Cranial Development ◽  
Future Assessment ◽  
The Central Nervous System ◽  
Cranial Fossa ◽  
Base Of The Skull

Anencephaly is a designation for congenital absence of the cranial vault with cerebral hemispheres completely missing or decreased to small masses attached to the base of the skull. The etiology is unknown. Whether the bony tissue or soft brain tissue is a primary factor is also unknown. The present study has focused on the posterior cranial fossa in anencephaly. The goal is to determine whether differences in the posterior cranial fossa could provide a basis for subclassification of anencephalic fetal skeletons. Twenty-three human anencephalic fetuses, at gestational ages 13 to 22 weeks, were studied. Radiologic and cephalometric analyses, including measurements of bone sizes and different angles, were performed. Permission for autopsy of the central nervous system was not available. For comparison of anencephalic findings with normal conditions, standards from a recent publication were used. Foot length served as a parameter for age comparison. The study showed 2 morphologic types of the posterior cranial fossa. One type had a fossa cranial morphology close to normal morphology, whereas the other had a malformed and much smaller posterior cranial fossa. The latter condition was presumed to be due to a primary error in chondral and cranial development. The current skeletal subgrouping might be essential for clinicians' or pathologists' future assessment of the autopsy results. The skeletal subgrouping should, if possible, be associated with karyotyping and analysis of the central nervous system. The goal is to distinguish between congenital conditions resulting in anencephaly and acquired conditions resulting in anencephaly.

scholarly journals Exploring Skeletal Diversity via Ring Contraction of Glycal-Derived Scaffolds.

ChemInform ◽  
2007 ◽  
Vol 38 (9) ◽  
Author(s):  
Adam R. Yeager ◽  
Geanna K. Min ◽  
John A. Jr. Porco ◽  
Scott E. Schaus
Keyword(s):  
Ring Contraction ◽  
Skeletal Diversity

ChemInform Abstract: Powerful Approach to Heterocyclic Skeletal Diversity by Sequential Three-Component Reaction of Amines, Isothiocyanates, and 1,2-Diaza-1,3-dienes.

ChemInform ◽  
2012 ◽  
Vol 43 (21) ◽  
pp. no-no
Author(s):  
Orazio A. Attanasi ◽  
Silvia Bartoccini ◽  
Gianfranco Favi ◽  
Gianluca Giorgi ◽  
Francesca Romana Perrulli ◽  
...  
Keyword(s):  
Three Component Reaction ◽  
Powerful Approach ◽  
Skeletal Diversity
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