Incident and long-term HIV-1 infection among pregnant women in Brazil: Transmitted drug resistance and mother-to-child transmission

2016 ◽  
Vol 88 (11) ◽  
pp. 1936-1943 ◽  
Author(s):  
Yanna Andressa Ramos Lima ◽  
Ludimila Paula Vaz Cardoso ◽  
Mônica Nogueira da Guarda Reis ◽  
Mariane Martins Araújo Stefani
2012 ◽  
Vol 54 (1) ◽  
pp. 15-20 ◽  
Author(s):  
Keila Correia Alcântara ◽  
Janaína Bacelar Accioli Lins ◽  
Maly Albuquerque ◽  
Letícia Mara Aires ◽  
Ludimila Paula Vaz Cardoso ◽  
...  

2019 ◽  
Vol 117 ◽  
pp. 89-95 ◽  
Author(s):  
Oladele Vincent Adeniyi ◽  
Chikwelu Larry Obi ◽  
Daniel Ter Goon ◽  
Benson Iweriebor ◽  
Anthony Idowu Ajayi ◽  
...  

Retrovirology ◽  
2008 ◽  
Vol 5 (Suppl 1) ◽  
pp. P12
Author(s):  
Jose-Henrique Pilotto ◽  
Beatriz Grinsztejn ◽  
Valdilea Veloso ◽  
Jose-Carlos Couto-Fernandez ◽  
Adriana Rodrigues-Pedro ◽  
...  

Author(s):  
William R. Short ◽  
Jason J. Schafer

Research has demonstrated that proper prevention strategies and interventions during pregnancy, labor, and delivery can significantly reduce the rate of mother-to-child transmission of HIV. Antiretroviral drugs (ARVs) should be initiated in all HIV-infected pregnant women regardless of CD4+ T cell count or HIV-1 RNA level. ARVs should be given in combination therapy, similar to nonpregnant patients, with the goal of complete virologic suppression. Treatment changes during pregnancy have been associated with the loss of virologic control and independently associated with mother-to-child transmission. All cases of prenatal antiretroviral exposure should be reported to the Antiretroviral Pregnancy Registry, which collects data on HIV-infected pregnant women taking ARVs with the goal of detecting any major teratogenic effects.


2003 ◽  
Vol 84 (3) ◽  
pp. 607-613 ◽  
Author(s):  
Natàlia Tàpia ◽  
Sandra Franco ◽  
Francesc Puig-Basagoiti ◽  
Clara Menéndez ◽  
Pedro Luis Alonso ◽  
...  

The present study was designed to assess whether the subtype of human immunodeficiency virus type 1 (HIV-1) could affect the rate of HIV-1 mother-to-child transmission in a cohort of 31 HIV-1-seropositive pregnant Tanzanian women. In order to assign a subtype to the samples analysed, nucleotide sequencing of the HIV-1 long terminal repeat U3 and C2V3C3 envelope regions was performed from the sera of these 31 pregnant women. Except in three cases, amplification of both regions was achieved in all samples. Subtypes A (n=13, 46 %), C (n=6, 21 %) and D (n=2, 7 %), as well as a number (25 %) of A/C, C/A, D/A and C/D recombinant forms (n=3, 2, 1 and 1, respectively), were identified. Of the 31 HIV-1 seropositive pregnant women analysed, eight (26 %) transmitted HIV-1 to their infants. Among the eight transmitter mothers, four (4 of 13, 31 %) were infected with HIV-1 subtype A, one (1 of 6, 17 %) with HIV-1 subtype C, none (0 of 2, 0 %) with HIV-1 subtype D and three (3 of 7, 43 %) with HIV-1 subtype recombinant A/C. These findings show no significant differences in the mother-to-child transmissibility of HIV-1 subtypes A, C and D and detected recombinants forms.


2019 ◽  
Vol 38 (5) ◽  
pp. 503-507 ◽  
Author(s):  
Frantz Jean Louis ◽  
Nathanael Segaren ◽  
Olbeg Desinor ◽  
R. Suzanne Beard ◽  
Reginald Jean-Louis ◽  
...  

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