Technical Decision-Making with Higher Order Structure Data: Detecting Reversible Concentration-Dependent Self-Association in a Monoclonal Antibody and a Preliminary Investigation to Eliminate It

2015 ◽  
Vol 104 (11) ◽  
pp. 3984-3989 ◽  
Author(s):  
Julie Y. Wei ◽  
George M. Bou-Assaf ◽  
Damian Houde ◽  
Andrew Weiskopf
Keyword(s):  
Decision Making ◽  
Monoclonal Antibody ◽  
Structure Data ◽  
Preliminary Investigation ◽  
Higher Order ◽  
Order Structure ◽  
Self Association

Technical Decision Making With Higher Order Structure Data: Perspectives on Higher Order Structure Characterization From the Biopharmaceutical Industry

2016 ◽  
Vol 105 (12) ◽  
pp. 3465-3470 ◽  
Author(s):  
William F. Weiss ◽  
John P. Gabrielson ◽  
Wasfi Al-Azzam ◽  
Guodong Chen ◽  
Darryl L. Davis ◽  
...  
Keyword(s):  
Decision Making ◽  
Structure Data ◽  
Higher Order ◽  
Structure Characterization ◽  
Order Structure ◽  
Biopharmaceutical Industry

Histone H1 and chromatin higher order structure does histone H1 exhibit specific self-association?

1983 ◽  
Vol 15 (4) ◽  
pp. 487-493 ◽  
Author(s):  
E. Russo ◽  
V. Giancotti ◽  
C. Crane-Robinson ◽  
G. Geraci
Keyword(s):  
Histone H1 ◽  
Higher Order ◽  
Order Structure ◽  
Self Association

scholarly journals Monoclonal antibody higher order structure analysis by high throughput protein conformational array

mAbs ◽  
2018 ◽  
Vol 10 (3) ◽  
pp. 397-405 ◽  
Author(s):  
Yuanli Song ◽  
Deqiang Yu ◽  
Mukesh Mayani ◽  
Nesredin Mussa ◽  
Zheng Jian Li
Keyword(s):  
Monoclonal Antibody ◽  
Structure Analysis ◽  
High Throughput ◽  
Higher Order ◽  
Order Structure

scholarly journals Enabling adoption of 2D-NMR for the higher order structure assessment of monoclonal antibody therapeutics

mAbs ◽  
2018 ◽  
Vol 11 (1) ◽  
pp. 94-105 ◽  
Author(s):  
Robert G. Brinson ◽  
John P. Marino ◽  
Frank Delaglio ◽  
Luke W. Arbogast ◽  
Ryan M. Evans ◽  
...  
Keyword(s):  
Monoclonal Antibody ◽  
2D Nmr ◽  
Higher Order ◽  
Order Structure ◽  
Antibody Therapeutics ◽  
Structure Assessment
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