Endoscopic Management of Benign Biliary Strictures After Liver Transplantation

2019 ◽  
Vol 25 (2) ◽  
pp. 323-335 ◽  
Author(s):  
Alberto Larghi ◽  
Andrea Tringali ◽  
Mihai Rimbaş ◽  
Federico Barbaro ◽  
Vincenzo Perri ◽  
...  
2012 ◽  
Vol 03 (S 05) ◽  
pp. 033-035
Author(s):  
Pierre H. Deprez

AbstractBenign biliary strictures for which endoscopic treatment is proposed are mostly related to liver transplantation or chronic pancreatitis (one third of cases each) and, less frequently, to other causes (e. g., cholecystectomy, sphincterotomy). The question of futility of exercise may therefore be of importance before embarking in these techniques. Endoscopic treatment of iatrogenic (post-operative) benign strictures may be considered as the gold standard since 90% of success is achieved with multiple stent placement. In strictures due to chronic pancreatitis, success rates are lower and surgery may be an appropriate alternative, although it may not be futile to propose an endoscopic try, especially when strictures are related to acute pancreatitis, pseudocyst obstruction or any reversible pancreatic cause of obstruction. In sclerosing cholangitis, endoscopic management is also focused on detection of malignancy. It should therefore not be considered as a futile exercise, but indications and aims of endotherapy should be discussed in a multidisciplinary team involving gastroenterologists, radiologists, and surgical specialists.


2012 ◽  
Vol 26 (9) ◽  
pp. 607-610 ◽  
Author(s):  
Kris P Croome ◽  
Vivian McAlister ◽  
Paul Adams ◽  
Paul Marotta ◽  
William Wall ◽  
...  

BACKGROUND Previous studies have shown a higher incidence of biliary complications following donation after cardiac death (DCD) liver transplantation compared with donation after brain death (DBD) liver transplantation. The endoscopic management of ischemic type biliary strictures in patients who have undergone DCD liver transplants needs to be characterized further.METHODS: A retrospective institutional review of all patients who underwent DCD liver transplant from January 2006 to September 2011 was performed. These patients were compared with all patients who underwent DBD liver transplantation in the same time period. A descriptive analysis of all DCD patients who developed biliary complications and their subsequent endoscopic management was also performed.RESULTS: Of the 36 patients who received DCD liver transplants, 25% developed biliary complications compared with 13% of patients who received DBD liver transplants (P=0.062). All DCD allograft recipients who developed biliary complications became symptomatic within three months of transplantation. Ischemic type biliary strictures in DCD allograft recipients included disseminated biliary strictures in two patients, biliary strictures of the hepatic duct bifurcation in three patients and biliary strictures of the donor common hepatic duct in three patients.CONCLUSIONS: There was a trend toward increasing incidence of total biliary complications in recipients of DCD liver allografts compared with those receiving DBD livers, and the rate of diffuse ischemic cholangiopathy was significantly higher. Focal ischemic type biliary strictures can be treated effectively in DCD liver transplant recipients with favourable results. Diffuse ischemic type biliary strictures in DCD liver transplant recipients ultimately requires retransplantation.


2006 ◽  
Vol 63 (5) ◽  
pp. AB306
Author(s):  
Jimin Han ◽  
Sung Koo Lee ◽  
Jong Cheol Kim Kim ◽  
Eun Kwang Choi ◽  
Dong Wan Seo ◽  
...  

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