scholarly journals Cancer biology functional genomics: From small RNAs to big dreams

2020 ◽  
Vol 59 (12) ◽  
pp. 1343-1361
Author(s):  
Soumya Sundara Rajan ◽  
Katelyn R. Ludwig ◽  
Katherine L. Hall ◽  
Tamara L. Jones ◽  
Natasha J. Caplen
Keyword(s):  
Functional Genomics ◽  
Small Rnas ◽  
Cancer Biology ◽  
Big Dreams

scholarly journals Functional Genomics for Cancer Research: Applications In Vivo and In Vitro

2019 ◽  
Vol 3 (1) ◽  
pp. 345-363 ◽  
Author(s):  
Thomas A. O'Loughlin ◽  
Luke A. Gilbert
Keyword(s):  
Cancer Research ◽  
Functional Genomics ◽  
Cancer Biology ◽  
Response To Therapy ◽  
Great Promise ◽  
Lethal Gene ◽  
Cancer Therapies ◽  
Cancer Phenotypes

Functional genomics holds great promise for the dissection of cancer biology. The elucidation of genetic cooperation and molecular details that govern oncogenesis, metastasis, and response to therapy is made possible by robust technologies for perturbing gene function coupled to quantitative analysis of cancer phenotypes resulting from genetic or epigenetic perturbations. Multiplexed genetic perturbations enable the dissection of cooperative genetic lesions as well as the identification of synthetic lethal gene pairs that hold particular promise for constructing innovative cancer therapies. Lastly, functional genomics strategies enable the highly multiplexed in vivo analysis of genes that govern tumorigenesis as well as of the complex multicellular biology of a tumor, such as immune response and metastasis phenotypes. In this review, we discuss both historical and emerging functional genomics approaches and their impact on the cancer research landscape.

Beyond Stamp Collecting: Evolutionary and Functional Genomics Advance Our Understanding of Cancer Biology

2021 ◽  
Vol 81 (7) ◽  
pp. 1637-1638
Author(s):  
Joseph Lachance
Keyword(s):  
Functional Genomics ◽  
Cancer Biology

Artificial Small RNAs for Functional Genomics in Plants

2021 ◽  
pp. 1-29
Author(s):  
Adriana E. Cisneros ◽  
Ainhoa de la Torre-Montaña ◽  
Tamara Martín-García ◽  
Alberto Carbonell
Keyword(s):  
Functional Genomics ◽  
Small Rnas

Abstract IA17: Functional genomics, small RNAs and cancer

2012 ◽  
Vol 72 (2 Supplement) ◽  
pp. IA17-IA17
Author(s):  
William C. Hahn
Keyword(s):  
Functional Genomics ◽  
Small Rnas

Abstract KP02: Functional genomics, cancer biology and targets

2015 ◽  
Author(s):  
William C. Hahn
Keyword(s):  
Functional Genomics ◽  
Cancer Biology

Functional information from magnetic resonance imaging

1995 ◽  
Vol 53 ◽  
pp. 84-85
Author(s):  
Alan P. Koretsky ◽  
Afonso Costa e Silva ◽  
Yi-Jen Lin
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
High Resolution ◽  
Cancer Biology ◽  
Imaging Modality ◽  
Magnetic Resonance Images ◽  
Great Success ◽  
Functional Information ◽  
Resonance Imaging ◽  
High Resolution Mri

Magnetic resonance imaging (MRI) has become established as an important imaging modality for the clinical management of disease. This is primarily due to the great tissue contrast inherent in magnetic resonance images of normal and diseased organs. Due to the wide availability of high field magnets and the ability to generate large and rapidly switched magnetic field gradients there is growing interest in applying high resolution MRI to obtain microscopic information. This symposium on MRI microscopy highlights new developments that are leading to increased resolution. The application of high resolution MRI to significant problems in developmental biology and cancer biology will illustrate the potential of these techniques.In combination with a growing interest in obtaining high resolution MRI there is also a growing interest in obtaining functional information from MRI. The great success of MRI in clinical applications is due to the inherent contrast obtained from different tissues leading to anatomical information.

Cancer biology: A game of subversion

Nature ◽  
2006 ◽  
Author(s):  
Emmanuelle Passegué
Keyword(s):  
Cancer Biology

Cancer biology: Consequences of changes

Nature China ◽  
2008 ◽  
Author(s):  
Jane Qiu
Keyword(s):  
Cancer Biology

Cancer biology: Studying a new subtype of prostate cancer

Nature China ◽  
2014 ◽  
Author(s):  
Piao Li
Keyword(s):  
Prostate Cancer ◽  
Cancer Biology

Cancer biology: Ridding the seeds of evil

Nature China ◽  
2012 ◽  
Author(s):  
Felix Cheung
Keyword(s):  
Cancer Biology
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