Validation and application of a fast Monte Carlo algorithm for assessing the clinical impact of approximations in analytical dose calculations for pencil beam scanning proton therapy

2018 ◽  
Vol 45 (12) ◽  
pp. 5631-5642 ◽  
Author(s):  
Sheng Huang ◽  
Kevin Souris ◽  
Siyang Li ◽  
Minglei Kang ◽  
Ana Maria Barragan Montero ◽  
...  
Keyword(s):  
Monte Carlo ◽  
Proton Therapy ◽  
Clinical Impact ◽  
Monte Carlo Algorithm ◽  
Pencil Beam ◽  
Dose Calculations ◽  
Beam Scanning ◽  
Pencil Beam Scanning

Improvements in pencil beam scanning proton therapy dose calculation accuracy in brain tumor cases with a commercial Monte Carlo algorithm

2018 ◽  
Vol 63 (14) ◽  
pp. 145016 ◽  
Author(s):  
Lamberto Widesott ◽  
Stefano Lorentini ◽  
Francesco Fracchiolla ◽  
Paolo Farace ◽  
Marco Schwarz
Keyword(s):  
Monte Carlo ◽  
Brain Tumor ◽  
Proton Therapy ◽  
Dose Calculation ◽  
Monte Carlo Algorithm ◽  
Pencil Beam ◽  
Beam Scanning ◽  
Pencil Beam Scanning

scholarly journals Experimental and Monte Carlo characterization of a dynamic collimation system prototype for pencil beam scanning proton therapy

2020 ◽  
Vol 47 (10) ◽  
pp. 5343-5356
Author(s):  
Blake R. Smith ◽  
Mark Pankuch ◽  
Daniel E. Hyer ◽  
Wesley S. Culberson
Keyword(s):  
Monte Carlo ◽  
Proton Therapy ◽  
Pencil Beam ◽  
Beam Scanning ◽  
Pencil Beam Scanning ◽  
Collimation System ◽  
System Prototype

scholarly journals Treatment of Ocular Tumors Through a Novel Applicator on a Conventional Proton Pencil Beam Scanning Beamline

2021 ◽  
Author(s):  
Rajesh Regmi ◽  
Dominic Maes ◽  
Alexander Nevitt ◽  
Allison Toltz ◽  
Erick Leuro ◽  
...  
Keyword(s):  
Proton Therapy ◽  
Pencil Beam ◽  
Small Field ◽  
Dose Calculations ◽  
Beam Scanning ◽  
Small Field Dosimetry ◽  
Pencil Beam Scanning ◽  
Monte Carlo Algorithms ◽  
Accurate Dose ◽  
Ocular Therapy

Abstract Treatment of ocular tumors on dedicated scattering-based proton therapy systems is standard afforded due to sharp lateral and distal penumbras. However, most newer proton therapy centers provide pencil beam scanning treatments. In this paper, we present a pencil beam scanning (PBS)-based ocular treatment solution. The design, commissioning, and validation of an applicator mount for a conventional PBS snout to allow for ocular treatments are given. In contrast to scattering techniques, PBS-based ocular therapy allows for inverse planning, providing planners with additional flexibility to shape the radiation field, potentially sparing healthy tissues. PBS enables the use of commercial Monte Carlo algorithms resulting in accurate dose calculations in the presence of heterogeneities and fiducials. The validation consisted of small field dosimetry measurements of point doses, depth doses, and lateral profiles relevant to ocular therapy. A comparison of beam properties achieved through the applicator against published literature is presented. We successfully showed the feasibility of PBS-based ocular treatments.

scholarly journals Monte Carlo study of the potential reduction in out-of-field dose using a patient-specific aperture in pencil beam scanning proton therapy

2012 ◽  
Vol 57 (10) ◽  
pp. 2829-2842 ◽  
Author(s):  
Stephen J Dowdell ◽  
Benjamin Clasie ◽  
Nicolas Depauw ◽  
Peter Metcalfe ◽  
Anatoly B Rosenfeld ◽  
...  
Keyword(s):  
Monte Carlo ◽  
Proton Therapy ◽  
Monte Carlo Study ◽  
Patient Specific ◽  
Pencil Beam ◽  
Beam Scanning ◽  
Potential Reduction ◽  
Pencil Beam Scanning

Development and validation of the Dynamic Collimation Monte Carlo simulation package for pencil beam scanning proton therapy

2021 ◽  
Author(s):  
Nicholas P. Nelson ◽  
Wesley S. Culberson ◽  
Daniel E. Hyer ◽  
Theodore J. Geoghegan ◽  
Kaustubh A. Patwardhan ◽  
...  
Keyword(s):  
Monte Carlo Simulation ◽  
Monte Carlo ◽  
Proton Therapy ◽  
Pencil Beam ◽  
Beam Scanning ◽  
Pencil Beam Scanning ◽  
Development And Validation ◽  
Simulation Package

Developing a Monte Carlo model for MEVION S250i with HYPERSCAN and Adaptive Aperture™ pencil beam scanning proton therapy system

2020 ◽  
pp. 1-8
Author(s):  
Bing-Hao Chiang ◽  
Austin Bunker ◽  
Hosang Jin ◽  
Salahuddin Ahmad ◽  
Yong Chen
Keyword(s):  
Monte Carlo ◽  
Proton Therapy ◽  
Monte Carlo Model ◽  
Particle Simulation ◽  
Planning System ◽  
Treatment Planning System ◽  
Pencil Beam ◽  
Beam Scanning ◽  
Pencil Beam Scanning ◽  
Beam Characteristics

Abstract Aim: As the number of proton therapy facilities has steadily increased, the need for the tool to provide precise dose simulation for complicated clinical and research scenarios also increase. In this study, the treatment head of Mevion HYPERSCAN pencil beam scanning (PBS) proton therapy system including energy modulation system (EMS) and Adaptive Aperture™ (AA) was modelled using TOPAS (TOolkit for PArticle Simulation) Monte Carlo (MC) code and was validated during commissioning process. Materials and methods: The proton beam characteristics including integral depth doses (IDDs) of pristine Bragg peak and in-air beam spot sizes were simulated and compared with measured beam data. The lateral profiles, with and without AA, were also verified against calculation from treatment planning system (TPS). Results: All beam characteristics for IDDs and in-air spot size agreed well within 1 mm and 10% separately. The full width at half maximum and penumbra of lateral dose profile also agree well within 2 mm. Finding: The TOPAS MC simulation of the MEVION HYPERSCAN PBS proton therapy system has been modelled and validated; it could be a viable tool for research and verification of the proton treatment in the future.

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