Use of a DVH overlay technique for quality assurance of deformable image registration‐based dose accumulation

2021 ◽  
Author(s):  
Kristofer Kainz ◽  
Juan Garcia Alvarez ◽  
Hualiang Zhong ◽  
Sara Lim ◽  
Ergun Ahunbay ◽  
...  
2017 ◽  
Vol 51 (4) ◽  
pp. 438-446 ◽  
Author(s):  
Wannapha Nobnop ◽  
Imjai Chitapanarux ◽  
Hudsaleark Neamin ◽  
Somsak Wanwilairat ◽  
Vicharn Lorvidhaya ◽  
...  

Abstract Introduction Deformable image registration (DIR) is used to modify structures according to anatomical changes for observing the dosimetric effect. In this study, megavoltage computed tomography (MVCT) images were used to generate cumulative doses for nasopharyngeal cancer (NPC) patients by various DIR methods. The performance of the multiple DIR methods was analysed, and the impact of dose accumulation was assessed. Patients and methods The study consisted of five NPC patients treated with a helical tomotherapy unit. The weekly MVCT images at the 1st, 6th, 11th, 16th, 21st, 26th, and 31st fractions were used to assess the dose accumulation by the four DIR methods. The cumulative dose deviations from the initial treatment plan were analysed, and correlations of these variations with the anatomic changes and DIR methods were explored. Results The target dose received a slightly different result from the initial plan at the end of the treatment. The organ dose differences increased as the treatment progressed to 6.8% (range: 2.2 to 10.9%), 15.2% (range: -1.7 to 36.3%), and 6.4% (range: -1.6 to 13.2%) for the right parotid, the left parotid, and the spinal cord, respectively. The mean uncertainty values to estimate the accumulated doses for all the DIR methods were 0.21 ± 0.11 Gy (target dose), 1.99 ± 0.76 Gy (right parotid), 1.19 ± 0.24 Gy (left parotid), and 0.41 ± 0.04 Gy (spinal cord). Conclusions Accuracy of the DIR methods affects the estimation of dose accumulation on both the target dose and the organ dose. The DIR methods provide an adequate dose estimation technique for observation as a result of inter-fractional anatomic changes and are beneficial for adaptive treatment strategies.


2021 ◽  
Vol 161 ◽  
pp. S1259-S1261
Author(s):  
F. Amstutz ◽  
P.G. D’Almeida ◽  
F. Albertini ◽  
L. Nenoff ◽  
D.C. Weber ◽  
...  

2020 ◽  
Vol 67 (4) ◽  
pp. 284-293 ◽  
Author(s):  
Molly Mee ◽  
Kate Stewart ◽  
Marika Lathouras ◽  
Helen Truong ◽  
Catriona Hargrave

2019 ◽  
Vol 19 (1) ◽  
pp. 25-29
Author(s):  
Warit Thongsuk ◽  
Imjai Chitapanarux ◽  
Somsak Wanwilairat ◽  
Wannapha Nobnop

AbstractPurpose:To evaluate changes of accumulated doses from an initial plan in each fraction by deformable image registration (DIR) with daily megavoltage computed tomography (MVCT) images from helical tomotherapy for prostate cancer patients.Materials and methods:The MVCT images of five prostate cancer patients were acquired by using a helical tomotherapy unit before the daily treatment fraction began. All images data were exported to DIR procedures by MIM software, in which the planned kilovoltage computed tomography (kVCT) images were acting as the source images with the daily MVCT acquired as the target images for registration. The automatic deformed structure was used to access the volume variation and daily dose accumulation to each structure. All dose-volume parameters were compared to the initial planned dose.Results:The actual median doses of the planning target volume (PTV) received 70 Gy and 50.4 Gy were decreased at the end of the treatment with an average 1·0 ± 0·67% and 2·1 ± 1·54%, respectively. As regards organs at risk (OARs), the bladder and rectum dose-volume parameters tended to increase from the initial plan. The high-dose regions of the bladder and rectum, however, were decreased from the initial plan at the end of the treatment.Conclusions:The daily actual dose differs from the initial planned dose. The accumulated dose of target tends to be lower than the initial plan, but tends to be higher than the initial plan for the OARs. Therefore, inter-fractional anatomic changes should be considered by the DIR methods, which would be useful as clinically informative and beneficial for adaptive treatment strategies.


2019 ◽  
Vol 46 (10) ◽  
pp. 4346-4355
Author(s):  
Juan Diego Azcona ◽  
Carlos Huesa‐Berral ◽  
Marta Moreno‐Jiménez ◽  
Benigno Barbés ◽  
José Javier Aristu ◽  
...  

2020 ◽  
Vol 65 (1) ◽  
pp. 015006 ◽  
Author(s):  
Cornel Zachiu ◽  
Baudouin Denis de Senneville ◽  
Bas W Raaymakers ◽  
Mario Ries

2014 ◽  
Vol 14 (4) ◽  
pp. 428-439 ◽  
Author(s):  
Haksoo Kim ◽  
Samuel B. Park ◽  
James I. Monroe ◽  
Bryan J. Traughber ◽  
Yiran Zheng ◽  
...  

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