Two new iridoids, 10-O-benzoylglobularigenin (1) and dumuloside (2) were isolated from the aerial parts of Globularia dumulosa together with seven known iridoid glucosides, davisioside (3), aucubin (4), melampyroside (5), catalpol (6), 10-O-benzoylcatalpol (7), alpinoside (8) and deacetylalpinoside (9). Three phenylethanoid glycosides, verbascoside, decaffeoylverbascoside, leucosceptoside A and three flavone glucosides, pectolinarigenin 7-O-β-ᴅ-glucopyranoside, nepetin 7-O-β-ᴅ-glucopyranoside, demethoxycentaureidin 7-O-β-ᴅ-glucopyranoside were also isolated and characterized. The structure elucidation of the isolated compounds was performed by spectroscopic (UV, IR, HR-MALDIMS, 1D- and 2D NMR) methods.
Iridoids from Globularia dumulosa