scholarly journals Survival Predictability Between the American Joint Committee on Cancer 8th Edition Staging System and the Barcelona Clinic Liver Cancer Classification in Patients with Hepatocellular Carcinoma

2020 ◽  
Author(s):  
Li‐Ju Chen ◽  
Yun‐Jau Chang ◽  
Yao‐Jen Chang
Keyword(s):  
Hepatocellular Carcinoma ◽  
Liver Cancer ◽  
Staging System ◽  
Cancer Classification ◽  
Barcelona Clinic Liver Cancer ◽  
American Joint Committee ◽  
8Th Edition

Surgical Treatment for Hepatocellular Carcinoma in the Era of Multiple Staging and Algorithm

2018 ◽  
Author(s):  
Suguru Yamashita ◽  
Katharina Joechle ◽  
Jean-Nicolas Vauthey
Keyword(s):  
Hepatocellular Carcinoma ◽  
Liver Cancer ◽  
Treatment Algorithm ◽  
Staging System ◽  
Cancer Staging ◽  
Barcelona Clinic Liver Cancer ◽  
Term Survival ◽  
American Joint Committee ◽  
Staging Systems ◽  
Surgical Treatments

A plethora of staging systems for hepatocellular carcinoma (HCC) has existed, as the management for HCC is made complex by the interplay of tumor characteristics and the health and underlying functions of both the patient and the liver. The majority of patients with HCC have nonsurgical HCC. The Barcelona Clinic Liver Cancer (BCLC) classification has been regarded as the optimal staging system and treatment algorithm for HCC. However, even in patients with intermediate or advanced stage in BCLC classification, who had not been originally recommended to undergo surgery, some could benefit in terms of long-term survival by surgical treatments. An expert panel on HCC has stated that the American Joint Committee on Cancer staging system, whose predictive power on the outcome have been improved by continuous amendments, should be applied for patients undergoing surgery. Herein, we review the recent staging system focusing on patients with HCC undergoing surgery.   This review contains 5 figures, 3 tables and 34 references Key Words: American Joint Committee on Cancer, Barcelona Clinic Liver Cancer, hepatic resection, hepatocellular carcinoma, orthotopic liver transplantation

Surgical Treatment for Hepatocellular Carcinoma in the Era of Multiple Staging and Algorithm

2018 ◽  
Author(s):  
Suguru Yamashita ◽  
Katharina Joechle ◽  
Jean-Nicolas Vauthey
Keyword(s):  
Hepatocellular Carcinoma ◽  
Liver Cancer ◽  
Treatment Algorithm ◽  
Staging System ◽  
Cancer Staging ◽  
Barcelona Clinic Liver Cancer ◽  
Term Survival ◽  
American Joint Committee ◽  
Staging Systems ◽  
Surgical Treatments

A plethora of staging systems for hepatocellular carcinoma (HCC) has existed, as the management for HCC is made complex by the interplay of tumor characteristics and the health and underlying functions of both the patient and the liver. The majority of patients with HCC have nonsurgical HCC. The Barcelona Clinic Liver Cancer (BCLC) classification has been regarded as the optimal staging system and treatment algorithm for HCC. However, even in patients with intermediate or advanced stage in BCLC classification, who had not been originally recommended to undergo surgery, some could benefit in terms of long-term survival by surgical treatments. An expert panel on HCC has stated that the American Joint Committee on Cancer staging system, whose predictive power on the outcome have been improved by continuous amendments, should be applied for patients undergoing surgery. Herein, we review the recent staging system focusing on patients with HCC undergoing surgery.   This review contains 5 figures, 3 tables and 34 references Key Words: American Joint Committee on Cancer, Barcelona Clinic Liver Cancer, hepatic resection, hepatocellular carcinoma, orthotopic liver transplantation

Barcelona Clinic Liver Cancer staging system and survival of untreated hepatocellular carcinoma in a hepatitis B virus endemic area

2015 ◽  
Vol 30 (4) ◽  
pp. 696-705 ◽  
Author(s):  
Jeong-Hoon Lee ◽  
Hwi Young Kim ◽  
Yoon Jun Kim ◽  
Jung-Hwan Yoon ◽  
Jin Wook Chung ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Hepatitis B Virus ◽  
Liver Cancer ◽  
Hepatitis B ◽  
Endemic Area ◽  
Staging System ◽  
Cancer Staging ◽  
Barcelona Clinic Liver Cancer ◽  
B Virus

A novel sub-staging system for prognosis prediction of Barcelona clinic liver cancer C stage hepatocellular carcinoma: 10 years observational study.

2021 ◽  
Vol 39 (15_suppl) ◽  
pp. e16139-e16139
Author(s):  
Zhiqiang Mo ◽  
Qicong Mai ◽  
Jian He ◽  
Xiaoming Chen
Keyword(s):  
Hepatocellular Carcinoma ◽  
Liver Cancer ◽  
Staging System ◽  
Predictive Performance ◽  
Interventional Therapy ◽  
Tumor Burden ◽  
Barcelona Clinic Liver Cancer ◽  
Related Factors ◽  
Linear Predictor ◽  
Individual Survival

e16139 Background: This study sought to propose a novel sub-staging system which could predict prognosis of patients with Barcelona clinic liver cancer (BCLC) C stage Hepatocellular carcinoma (HCC). Methods: Between January 2008 and September 2018, 806 patients with BCLC-C stage HCC were assessed retrospectively. The significance of clinical variables in predicting prognosis were statistical analysis. A prognostic sub-staging system of BCLC-C stage HCC was developed according to prognosis-related factors. The predictive performance was subsequently validated. Results: In training set, tumor burden (TB) >50%, type III/IV portal vein tumor thrombus (PVTT), extrahepatic metastasis (M) and Child-Pugh (CP) B class were independently associated with overall survival (OS). According to those prognosis-related factors, a novel sub-staging system of BCLC-C stage was “linear predictor= TB+PVTT+M+CP”, which had good performance in predicting OS in both training and validation set. The thirtieth percentile and the third quartile of the linear predictor, namely 6 and 12, were selected as cut-off values, stratifying patients into different OS after interventional therapy (IT) or sorafenib therapy (ST), specifically, ≤6: 43.7 months for IT, 32.0 month for ST;＞6 but＜12: 43.7 months for IT, 32.0 month for ST; ≥12: 43.7 months for IT, 32.0 month for ST. Conclusions: The novel sub-staging system of BCLC-C stage HCC may stratify patients for suitable therapy and predict individual survival with favorable performance and discrimination.

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