Synthesis and biological activity of analogs of the antifungal antibiotic UK‐2A. II. Impact of modifications to the macrocycle benzyl position

2019 ◽  
Vol 75 (7) ◽  
pp. 1831-1846 ◽  
Author(s):  
W John Owen ◽  
Kevin G Meyer ◽  
Stacy T Meyer ◽  
Fangzheng Li ◽  
Thomas J Slanec ◽  
...  
Keyword(s):  
Biological Activity ◽  
Antifungal Antibiotic

scholarly journals A novel macrolactam-disaccharide antifungal antibiotic. Taxonomy, fermentation, isolation, physico-chemical properties, structure elucidation and biological activity.

1993 ◽  
Vol 46 (7) ◽  
pp. 1109-1115 ◽  
Author(s):  
VINOD R. HEGDE ◽  
MAHESH G. PATEL ◽  
VINCENT P. GULLO ◽  
ANN C. HORAN ◽  
ARTHUR H. KING ◽  
...  
Keyword(s):  
Biological Activity ◽  
Structure Elucidation ◽  
Chemical Properties ◽  
Antifungal Antibiotic ◽  
Physico Chemical

scholarly journals Cepacidine A, a novel antifungal antibiotic produced by Pseudomonas cepacia. I. Taxonomy, production, isolation and biological activity.

1994 ◽  
Vol 47 (12) ◽  
pp. 1402-1405 ◽  
Author(s):  
CHUL-HOON LEE ◽  
SUNGHO KIM ◽  
BONGCHUL HYUN ◽  
JUNG-WOO SUH ◽  
CHANGSUEK YON ◽  
...  
Keyword(s):  
Biological Activity ◽  
Pseudomonas Cepacia ◽  
Antifungal Antibiotic

ChemInform Abstract: Cepacidine A, a Novel Antifungal Antibiotic Produced by Pseudomonas cepacia. Part 1. Taxonomy, Production, Isolation and Biological Activity.

ChemInform ◽  
2010 ◽  
Vol 26 (23) ◽  
pp. no-no
Author(s):  
C. LEE ◽  
S. KIM ◽  
B. HYUN ◽  
J. SUH ◽  
C. YON ◽  
...  
Keyword(s):  
Biological Activity ◽  
Pseudomonas Cepacia ◽  
Antifungal Antibiotic

scholarly journals FR109615, a new antifungal antibiotic from Streptomyces setonii. Taxonomy, fermentation, isolation, physico-chemical properties and biological activity.

1990 ◽  
Vol 43 (1) ◽  
pp. 1-7 ◽  
Author(s):  
TOSHIRO IWAMOTO ◽  
EISAKU TSUJII ◽  
MASAMI EZAKI ◽  
AKIHIKO FUJIE ◽  
SEIJI HASHIMOTO ◽  
...  
Keyword(s):  
Biological Activity ◽  
Chemical Properties ◽  
Antifungal Antibiotic ◽  
Physico Chemical

Synthesis and biological activity of analogs of the antifungal antibiotic UK-2A. I. Impact of picolinamide ring replacement

2018 ◽  
Vol 75 (2) ◽  
pp. 413-426 ◽  
Author(s):  
W John Owen ◽  
Kevin G Meyer ◽  
Thomas J Slanec ◽  
Nick X Wang ◽  
Stacy T Meyer ◽  
...  
Keyword(s):  
Biological Activity ◽  
Antifungal Antibiotic

scholarly journals A Novel Macrolactam-trisaccharide Antifungal Antibiotic. Taxonomy, Fermentation, Isolation, Physico-chemical Properties, Structure Elucidation and Biological Activity.

1998 ◽  
Vol 51 (5) ◽  
pp. 464-470 ◽  
Author(s):  
VINOD R. HEGDE ◽  
MAHESH G. PATEL ◽  
ANN C. HORAN ◽  
ARTHUR H. KING ◽  
FRANK GENTILE ◽  
...  
Keyword(s):  
Biological Activity ◽  
Structure Elucidation ◽  
Chemical Properties ◽  
Antifungal Antibiotic ◽  
Physico Chemical

Synthesis and biological activity of analogs of the antifungal antibiotic UK‐2A. III. Impact of modifications to the macrocycle isobutyryl ester position

2019 ◽  
Vol 76 (1) ◽  
pp. 277-286 ◽  
Author(s):  
W John Owen ◽  
Kevin G Meyer ◽  
Thomas J Slanec ◽  
Stacy T Meyer ◽  
Nick X Wang ◽  
...  
Keyword(s):  
Biological Activity ◽  
Antifungal Antibiotic

ChemInform Abstract: A Novel Macrolactam-trisaccharide Antifungal Antibiotic Taxonomy, Fermentation, Isolation, Physico-chemical Properties, Structure Elucidation and Biological Activity.

ChemInform ◽  
2010 ◽  
Vol 29 (43) ◽  
pp. no-no
Author(s):  
V. R. HEGDE ◽  
M. G. PATEL ◽  
A. C. HORAN ◽  
A. H. KING ◽  
F. GENTILE ◽  
...  
Keyword(s):  
Biological Activity ◽  
Structure Elucidation ◽  
Chemical Properties ◽  
Antifungal Antibiotic ◽  
Physico Chemical

Virus-Like Particles in a Human Breast Cancer: Structural Similarity to Previously Reported Particles

1973 ◽  
Vol 31 ◽  
pp. 378-379
Author(s):  
G. Kasnic ◽  
S. E. Stewart ◽  
C. Urbanski
Keyword(s):  
Breast Cancer ◽  
Biological Activity ◽  
Human Breast Cancer ◽  
Osteogenic Sarcoma ◽  
Human Tumor ◽  
Structural Similarity ◽  
Cell Tumor ◽  
Human Breast ◽  
Human Tumor Cell ◽  
Type Particle

We have reported the maturation of an intracisternal A-type particle in murine plasma cell tumor cultures and three human tumor cell cultures (rhabdomyosarcoma, lung adenocarcinoma, and osteogenic sarcoma) after IUDR-DMSO activation. In all of these studies the A-type particle seems to develop into a form with an electron dense nucleoid, presumably mature, which is also intracisternal. A similar intracisternal A-type particle has been described in leukemic guinea pigs. Although no biological activity has yet been demonstrated for these particles, on morphologic grounds, and by the manner in which they develop within the cell, they may represent members of the same family of viruses.

Effects of Vincristine on Endothelial Microtubules in the Spinal Cord

1976 ◽  
Vol 34 ◽  
pp. 58-59
Author(s):  
John L. Beggs ◽  
John D. Waggener ◽  
Wanda Miller
Keyword(s):  
Spinal Cord ◽  
Biological Activity ◽  
Horseradish Peroxidase ◽  
Transport Mechanism ◽  
Vasogenic Edema ◽  
Vesicular Transport ◽  
Close Proximity

Microtubules (MT) are versatile organelles participating in a wide variety of biological activity. MT involvement in the movement and transport of cytoplasmic components has been well documented. In the course of our study on trauma-induced vasogenic edema in the spinal cord we have concluded that endothelial vesicles contribute to the edema process. Using horseradish peroxidase as a vascular tracer, labeled endothelial vesicles were present in all situations expected if a vesicular transport mechanism was in operation. Frequently,labeled vesicles coalesced to form channels that appeared to traverse the endothelium. The presence of MT in close proximity to labeled vesicles sugg ested that MT may play a role in vesicular activity.

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