Synthesis and purification of self-assembling peptide-oligonucleotide conjugates by solid-phase peptide fragment condensation

2018 ◽  
Vol 24 (8-9) ◽  
pp. e3092 ◽  
Author(s):  
Mahnseok Kye ◽  
Yong-beom Lim
Keyword(s):  
Solid Phase ◽  
Peptide Fragment ◽  
Self Assembling ◽  
Fragment Condensation ◽  
Oligonucleotide Conjugates

An alternative solid phase peptide fragment condensation protocol with improved efficiency

2001 ◽  
Vol 7 (10) ◽  
pp. 565-568 ◽  
Author(s):  
Nikolett Mihala ◽  
József Bódi ◽  
Ágnes Gömöry ◽  
Helga Süli-Vargha
Keyword(s):  
Solid Phase ◽  
Peptide Fragment ◽  
Fragment Condensation

Oxytocin analogues with non-coded amino acid residues in position 8: [8-Neopentylglycine]oxytocin and [8-cycloleucine]oxytocin

1987 ◽  
Vol 52 (9) ◽  
pp. 2317-2325 ◽  
Author(s):  
Jan Hlaváček ◽  
Jan Pospíšek ◽  
Jiřina Slaninová ◽  
Walter Y. Chan ◽  
Victor J. Hruby
Keyword(s):  
Amino Acid ◽  
Solid Phase Synthesis ◽  
Solid Phase ◽  
The Other ◽  
Amino Acid Residues ◽  
Phase Synthesis ◽  
Other Hand ◽  
Fragment Condensation

[8-Neopentylglycine]oxytocin (II) and [8-cycloleucine]oxytocin (III) were prepared by a combination of solid-phase synthesis and fragment condensation. Both analogues exhibited decreased uterotonic potency in vitro, each being about 15-30% that of oxytocin. Analogue II also displayed similarly decreased uterotonic potency in vivo and galactogogic potency. On the other hand, analogue III exhibited almost the same potency as oxytocin in the uterotonic assay in vivo and in the galactogogic assay.

Solid-phase fragment condensation for synthesis of peptides from the immunodominant sequence of β1-adrenoreceptor

2017 ◽  
Vol 43 (4) ◽  
pp. 351-358 ◽  
Author(s):  
M. V. Sidorova ◽  
M. E. Palkeeva ◽  
A. A. Az’muko ◽  
M. V. Ovchinnikov ◽  
A. S. Molokoedov ◽  
...  
Keyword(s):  
Solid Phase ◽  
Fragment Condensation

Solid-phase synthesis of carboxyamidomethyl peptide esters: Application to enzymatic fragment condensation

Peptides 1992 ◽  
1993 ◽  
pp. 423-424 ◽  
Author(s):  
P. Clapés ◽  
Y. M. Sanchez ◽  
F. Albericio ◽  
J. L. Torres ◽  
G. Valencia
Keyword(s):  
Solid Phase Synthesis ◽  
Solid Phase ◽  
Phase Synthesis ◽  
Fragment Condensation ◽  
Peptide Esters

Reaction medium engineering in enzymatic peptide fragment condensation: synthesis of Eledoisin and LH-RH

1998 ◽  
Vol 6 (7) ◽  
pp. 891-901 ◽  
Author(s):  
Peter Björup ◽  
Josep Lluı́s Torres ◽  
Patrick Adlercreutz ◽  
Pere Clapés
Keyword(s):  
Reaction Medium ◽  
Peptide Fragment ◽  
Fragment Condensation ◽  
Lh Rh

Emerging applications of peptide–oligonucleotide conjugates: bioactive scaffolds, self-assembling systems, and hybrid nanomaterials

2019 ◽  
Vol 17 (7) ◽  
pp. 1668-1682 ◽  
Author(s):  
Tara MacCulloch ◽  
Alex Buchberger ◽  
Nicholas Stephanopoulos
Keyword(s):  
Synthetic Peptide ◽  
Hybrid Nanomaterials ◽  
Bioactive Scaffolds ◽  
Self Assembling ◽  
Oligonucleotide Conjugates

Peptide–oligonucleotide conjugates (POCs) are covalent constructs that link a molecule like DNA to a synthetic peptide sequences.

Histone Model Peptide Synthetized by Solid Phase Fragment Condensation

1983 ◽  
pp. 223-226
Author(s):  
Vladimír Gut ◽  
Hana Votavová ◽  
Karol Bláha ◽  
Jaroslav Šponar
Keyword(s):  
Solid Phase ◽  
Model Peptide ◽  
Fragment Condensation
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