Incorporation and characterization of boron neutron capture therapy agents into mesoporous silicon and silicon nanowires

2009 ◽  
Vol 206 (6) ◽  
pp. 1361-1364 ◽  
Author(s):  
Ke Jiang ◽  
Armando Loni ◽  
Leigh T. Canham ◽  
Jeffery L. Coffer
Keyword(s):  
Silicon Nanowires ◽  
Boron Neutron Capture Therapy ◽  
Neutron Capture ◽  
Neutron Capture Therapy ◽  
Mesoporous Silicon ◽  
Boron Neutron Capture

Experimental and Simulated Characterization of a Beam Shaping Assembly for Accelerator- Based Boron Neutron Capture Therapy (AB-BNCT)

2010 ◽  
Author(s):  
Alejandro A. Burlon ◽  
Santiago Girola ◽  
Alejandro A. Valda ◽  
Daniel M. Minsky ◽  
Andrés J. Kreiner ◽  
...  
Keyword(s):  
Boron Neutron Capture Therapy ◽  
Neutron Capture ◽  
Beam Shaping ◽  
Neutron Capture Therapy ◽  
Boron Neutron Capture ◽  
Beam Shaping Assembly

scholarly journals Synthesis and characterization of azanonaborane-containing purine derivatives for boron neutron capture therapy

2008 ◽  
Vol 6 (2) ◽  
pp. 154-160
Author(s):  
Afaf Genady ◽  
Mohamed El-Zaria ◽  
Detlef Gabel
Keyword(s):  
Boron Neutron Capture Therapy ◽  
Neutron Capture ◽  
Imidazole Ring ◽  
Pyrimidine Ring ◽  
Neutron Capture Therapy ◽  
Reaction Conditions ◽  
Ligand Exchange Reaction ◽  
Boron Neutron Capture ◽  
Derivatives Of

AbstractDerivatives of purine, adenine, guanine, and 2,6-diaminopurine linked to the azanonaborane (B8N cluster) have been prepared, for possible use as powerful agents for boron neutron capture therapy (BNCT). The synthesis was carried out via a ligand exchange reaction. The exo-NH2R group of the azanonaborane of the type [(RH2N)B8H11NHR] can be exchanged by one hetero-nitrogen atom of the pyrimidine ring, and except for guanine, also by an N atom of the imidazole ring. The identity of the products was confirmed by NMR, elemental analysis, IR, and mass spectrometry. No reaction was found to occur with caffeine and theophylline under the same reaction conditions.

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