scholarly journals Concise Review: Lessons Learned from Islet Transplant Clinical Trials in Developing Stem Cell Therapies for Type 1 Diabetes

2018 ◽  
Vol 8 (3) ◽  
pp. 209-214 ◽  
Author(s):  
Carole A. Welsch ◽  
William L. Rust ◽  
Marie Csete
Keyword(s):  
Clinical Trials ◽  
Type 1 Diabetes ◽  
Stem Cell ◽  
Lessons Learned ◽  
Stem Cell Therapies ◽  
Cell Therapies ◽  
Islet Transplant ◽  
Concise Review

scholarly journals Latest Therapies for Type 1 Diabetes: Exsisting Setup and “Post-Insulin” Standpoints

2020 ◽  
Author(s):  
AMMIRA-SARAH AL-SHABEEB AKIL ◽  
Aljazi Al-Maraghi ◽  
ESRAA YASSIN ◽  
KHULOD AL-MALKI ◽  
KHALID FAKHRO
Keyword(s):  
Type 1 Diabetes ◽  
Stem Cell ◽  
Standard Of Care ◽  
Stem Cell Therapies ◽  
Cell Therapies ◽  
Long Acting ◽  
Near Future ◽  
Careful Management

Type 1 diabetes affects millions of people globally and requires careful management to avoid serious long-term complications, including heart and kidney disease, stroke, and loss of sight. The present standard-of-care for type 1 diabetes is exogenic insulin substitutional therapy. The most advanced stretegies in this area is the development of hybrid-closed loop system and the producing of long-acting insulins. Progresses in stem cell therapies have started to revolutionize the care of patients with type 1 diabetes; however, significant challenges remain including the limited islets availability, difficulties in maintaining the viability, the heterogeneity within a complex pathology and in patients’ responses to treatment. On the way, a considerable amount of efforts in maximizing the islet transplantation effectiveness by controlling the advantageous of different stem cell approaches. With the availability and the use of big data, the concept of precision medicine is gaining wide attention worldwide and could bring the dream of “presonlaized” therapies as a reality in the near future. Here we review the current range of treatments available as well as recent pre-clinical breakthroughs in the field of personlaized medicine for type 1 diabetes.

Feasibility of Induced Pluripotent Stem Cell Therapies for Treatment of Type 1 Diabetes

2018 ◽  
Vol 24 (6) ◽  
pp. 482-492
Author(s):  
Caden Duffy ◽  
Cesar Prugue ◽  
Rachel Glew ◽  
Taryn Smith ◽  
Calvin Howell ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Stem Cell ◽  
Pluripotent Stem Cell ◽  
Induced Pluripotent Stem Cell ◽  
Stem Cell Therapies ◽  
Cell Therapies ◽  
Induced Pluripotent

scholarly journals Concise Review: Markers for Assessing Human Stem Cell-Derived Implants as β-Cell Replacement in Type 1 Diabetes

2016 ◽  
Vol 5 (10) ◽  
pp. 1338-1344 ◽  
Author(s):  
Daniel Pipeleers ◽  
Thomas Robert ◽  
Ines De Mesmaeker ◽  
Zhidong Ling
Keyword(s):  
Type 1 Diabetes ◽  
Stem Cell ◽  
Human Stem Cell ◽  
Β Cell ◽  
Cell Replacement ◽  
Concise Review

scholarly journals Concise Review: Using Fat to Fight Disease: A Systematic Review of Nonhomologous Adipose-Derived Stromal/Stem Cell Therapies

Stem Cells ◽  
2018 ◽  
Vol 36 (9) ◽  
pp. 1311-1328 ◽  
Author(s):  
Marjorie E. Bateman ◽  
Amy L. Strong ◽  
Jeffrey M. Gimble ◽  
Bruce A. Bunnell
Keyword(s):  
Systematic Review ◽  
Stem Cell ◽  
Stem Cell Therapies ◽  
Cell Therapies ◽  
Concise Review ◽  
Stromal Stem Cell

scholarly journals Stem cell therapies for ischemic stroke: current animal models, clinical trials and biomaterials

RSC Advances ◽  
2017 ◽  
Vol 7 (30) ◽  
pp. 18668-18680 ◽  
Author(s):  
Hugh H. Chan ◽  
Connor A. Wathen ◽  
Ming Ni ◽  
Shuangmu Zhuo
Keyword(s):  
Tissue Engineering ◽  
Clinical Trials ◽  
Stem Cell ◽  
Ischemic Stroke ◽  
Animal Models ◽  
Cell Therapy ◽  
Stem Cell Therapy ◽  
Stem Cell Therapies ◽  
Cell Therapies

We report the facilitation of stem cell therapy in stroke by tissue engineering and applications of biomaterials.

scholarly journals Concise Review: Stem Cell Therapies for Neuropathic Pain

2013 ◽  
Vol 2 (5) ◽  
pp. 394-399 ◽  
Author(s):  
Veronica R. Fortino ◽  
Daniel Pelaez ◽  
Herman S. Cheung
Keyword(s):  
Neuropathic Pain ◽  
Stem Cell ◽  
Stem Cell Therapies ◽  
Cell Therapies ◽  
Concise Review

scholarly journals Stem Cell Therapies in Clinical Trials: Workshop on Best Practices and the Need for Harmonization

2010 ◽  
Vol 7 (4) ◽  
pp. 451-454 ◽  
Author(s):  
Karen Martell ◽  
Alan Trounson ◽  
Elona Baum
Keyword(s):  
Clinical Trials ◽  
Stem Cell ◽  
Best Practices ◽  
Stem Cell Therapies ◽  
Cell Therapies
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