scholarly journals First-trimester uterine artery Doppler and adverse pregnancy outcome: a meta-analysis involving 55 974 women

2014 ◽  
Vol 43 (5) ◽  
pp. 500-507 ◽  
Author(s):  
L. Velauthar ◽  
M. N. Plana ◽  
M. Kalidindi ◽  
J. Zamora ◽  
B. Thilaganathan ◽  
...  
Keyword(s):  
Pregnancy Outcome ◽  
Uterine Artery ◽  
Adverse Pregnancy Outcome ◽  
Meta Analysis ◽  
First Trimester ◽  
Uterine Artery Doppler ◽  
Adverse Pregnancy

scholarly journals Uterine Artery Doppler in the Prediction of Preeclampsia and Adverse Pregnancy Outcome

2010 ◽  
Vol 4 (2) ◽  
pp. 117-122
Author(s):  
George Daskalakis ◽  
Aris Antsaklis
Keyword(s):  
Pregnancy Outcome ◽  
Uterine Artery ◽  
Adverse Pregnancy Outcome ◽  
False Positive Rate ◽  
First Trimester ◽  
Maternal Serum ◽  
Uterine Artery Doppler ◽  
Mortality And Morbidity ◽  
Increased Risk ◽  
Adverse Pregnancy

Abstract Preeclampsia and fetal growth restriction are major causes of perinatal mortality and morbidity. Several studies have shown that a generalized endothelial dysfunction is associated with these complications. Clinical trials have shown that pregnant women who demonstrate high resistance in uteroplacental blood flow are at higher risk for preeclampsia. Uterine artery Doppler studies both in the second and the first trimester can predict pregnancies at increased risk of the complications of impaired placentation. The sensitivity for predicting severe preeclampsia ranges between 80 and 90% for a false positive rate of 5 to 7%. Uterine artery Doppler screening at 20 to 24 weeks’ gestation is superior to first trimester screening, and appears to fulfill the requirements for a worthwhile screening test. Further research is needed to better assess the value of various combinations of uterine artery Doppler and maternal serum markers, for the prediction of adverse pregnancy outcome.

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