scholarly journals VP32.02: Hyperimmunoglobulin therapy in pregnant women with primary cytomegalovirus infection

2021 ◽  
Vol 58 (S1) ◽  
pp. 233-233
Author(s):  
N. Schirwani ◽  
P. Palmrich ◽  
H. Kiss ◽  
D. Prayer ◽  
J. Binder
2012 ◽  
Vol 85 (2) ◽  
pp. 315-319 ◽  
Author(s):  
Harshita Rajasekariah ◽  
Gillian Scott ◽  
Peter W. Robertson ◽  
William D. Rawlinson

2012 ◽  
Vol 19 (12) ◽  
pp. 1991-1993 ◽  
Author(s):  
Ennio Polilli ◽  
Giustino Parruti ◽  
Francesca D'Arcangelo ◽  
Elisa Tracanna ◽  
Luigi Clerico ◽  
...  

ABSTRACTHyperimmune globulins were reported to prevent and treat fetal cytomegalovirus (CMV) infection during pregnancy. Here, we report that infusions of standard human intravenous immunoglobulin significantly increase CMV IgG titers and avidity indexes in pregnant women, paving the way to their use for passive transfer of maternal CMV humoral immunity to fetuses. Preliminary data on perinatal outcomes of the first 67 newborns are encouraging.


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