OP09.10: 3D ultrasound imaging and reproducibility of nasal bone length, prenasal thickness and fronto-maxillary facial angle in normal second and third trimester fetuses

2010 ◽  
Vol 36 (S1) ◽  
pp. 79-79
Author(s):  
F. I. Vos ◽  
E. de Jong-Pleij ◽  
C. M. Bilardo
Keyword(s):  
Ultrasound Imaging ◽  
Nasal Bone ◽  
3D Ultrasound ◽  
Third Trimester ◽  
Bone Length ◽  
Nasal Bone Length

Trends in Serial Measurements of Ultrasound Markers in Second and Third Trimester Down Syndrome Fetuses

2015 ◽  
Vol 38 (1) ◽  
pp. 48-54 ◽  
Author(s):  
F.I. Vos ◽  
E.A.P. De Jong-Pleij ◽  
M. Bakker ◽  
E. Tromp ◽  
C.M. Bilardo
Keyword(s):  
Down Syndrome ◽  
Heart Defects ◽  
Nasal Bone ◽  
Third Trimester ◽  
Bone Length ◽  
Normal Ranges ◽  
Nasal Bone Length ◽  
Serial Measurements ◽  
Space Ratio ◽  
Median Interval

Objectives: To evaluate trends of nasal bone length (NBL), prenasal thickness (PT), nuchal fold (NF), prenasal thickness to nasal bone length (PT-NBL) ratio, and prefrontal space ratio (PFSR), measured serially in second- and third-trimester Down syndrome (DS) fetuses. Methods: Prenatal databases were searched for cases of continuing DS pregnancies with serial measurements, taken at least two weeks apart. Trends were plotted on previously reported normal ranges. Results: Serial measurements were available in 25 Down syndrome fetuses. Median gestational age (GA) was 25 weeks; average number of visits per case was 2.44, with a median interval of 39 days between investigations. In DS fetuses, NBL and PT showed fairly stable trends with gestation. PFSR, but especially NF, had a more unpredictable trend. The PT-NBL ratio was the most stable marker, remaining unchanged in 95% of cases. NBL, PT, and NF showed more deviance from the normal range with advancing gestation, but MoM values remained stable. All but two fetuses had ultrasound markers or structural anomalies, especially heart defects. Conclusions: The PT-NBL ratio is the most constant DS marker throughout gestation, following a predictable trend.

scholarly journals P15.11: Trends in prenasal thickness, nasal bone length and nuchal fold thickness measurements in second and third trimester Down syndrome fetuses

2009 ◽  
Vol 34 (S1) ◽  
pp. 235-235
Author(s):  
F. I. Vos ◽  
E. A. de Jong-Pleij ◽  
E. Timmerman ◽  
L. R. Pistorius ◽  
E. Pajkrt ◽  
...  
Keyword(s):  
Down Syndrome ◽  
Nasal Bone ◽  
Third Trimester ◽  
Bone Length ◽  
Nasal Bone Length ◽  
Thickness Measurements

Prenasal thickness-to-nasal bone length ratio: a strong and simple second- and third-trimester marker for trisomy 21

2011 ◽  
Vol 39 (2) ◽  
pp. 185-190 ◽  
Author(s):  
E. A. P. De Jong-Pleij ◽  
F. I. Vos ◽  
L. S. M. Ribbert ◽  
L. R. Pistorius ◽  
E. Tromp ◽  
...  
Keyword(s):  
Trisomy 21 ◽  
Nasal Bone ◽  
Length Ratio ◽  
Third Trimester ◽  
Bone Length ◽  
Nasal Bone Length

scholarly journals OC18.01: The prenasal thickness to nasal bone length ratio: 2D versus 3D ultrasound

2013 ◽  
Vol 42 (s1) ◽  
pp. 35-36
Author(s):  
E. de Jong ◽  
F. Vos ◽  
K. Kagan ◽  
L.S. Ribbert ◽  
E. Tromp ◽  
...  
Keyword(s):  
Nasal Bone ◽  
3D Ultrasound ◽  
Length Ratio ◽  
Bone Length ◽  
Nasal Bone Length
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