Utility of preputial cytology to diagnose hyperoestrogenism in a dog with an intra‐abdominal Sertoli cell tumour with concurrent thrombocytopaenia and intracranial haemorrhage

2021 ◽  
Author(s):  
Simone M. Cutler ◽  
Maverick Melega ◽  
Liam Wilson ◽  
Craig R. Breheny ◽  
Juan‐Carlos Serra
Keyword(s):  
Sertoli Cell ◽  
Intracranial Haemorrhage ◽  
Cell Tumour ◽  
Sertoli Cell Tumour

Germline mutation in the STK11 gene in a girl with an ovarian Sertoli cell tumour

2006 ◽  
Vol 166 (10) ◽  
pp. 1083-1085 ◽  
Author(s):  
Guy Massa ◽  
Nele Roggen ◽  
Marleen Renard ◽  
Johan J. P. Gille
Keyword(s):  
Sertoli Cell ◽  
Germline Mutation ◽  
Cell Tumour ◽  
Stk11 Gene ◽  
Sertoli Cell Tumour

scholarly journals MALIGNANT SERTOLI CELL TUMOUR: AN UNCOMMON TESTICULAR TUMOUR

2006 ◽  
Vol 9 (2) ◽  
pp. 18-21
Author(s):  
Sia SF ◽  
Dublin N ◽  
Nurul B ◽  
Wong KT
Keyword(s):  
Sertoli Cell ◽  
Cell Tumour ◽  
Testicular Tumour ◽  
Sertoli Cell Tumour

Large-Cell Calcifying Sertoli Cell Tumour of the Testis Detected at Screening of a Family with Carney Syndrome

2005 ◽  
Vol 75 (4) ◽  
pp. 365-367 ◽  
Author(s):  
S.N. Jayasena ◽  
J.T.N. Ariyasinghe ◽  
D.M.R. Gunawardena ◽  
S.A.S. Gunawardena ◽  
M.V.C. de Silva
Keyword(s):  
Sertoli Cell ◽  
Large Cell ◽  
Cell Tumour ◽  
Sertoli Cell Tumour ◽  
Carney Syndrome

STEROID METABOLISM OF A SERTOLI CELL TUMOUR OF THE TESTIS OF A DOG WITH FEMINIZATION AND ALOPECIA AND OF THE NORMAL CANINE TESTIS

1967 ◽  
Vol 38 (1) ◽  
pp. 61-NP ◽  
Author(s):  
C. G. PIERREPOINT ◽  
JEAN McI. GALLEY ◽  
K. GRIFFITHS ◽  
J. K. GRANT
Keyword(s):  
Sertoli Cell ◽  
Direct Evidence ◽  
Hydroxysteroid Dehydrogenase ◽  
Testicular Tissue ◽  
Cell Tumour ◽  
Tumour Tissue ◽  
Steroid Metabolism ◽  
Enzyme Systems ◽  
Sertoli Cell Tumour

SUMMARY The metabolism of [7α-3H]pregnenolone and [4-14C]dehydroepiandrosterone (DHA) by a Sertoli cell tumour of the testis from a dog with signs of feminization has been studied in vitro and compared with the metabolism of the normal canine testis. The tumour formed oestrone and oestradiol-17β from DHA thus providing direct evidence for the synthesis of oestrogen by this type of neoplasm. Relative or complete inactivity of several enzyme systems involved in the synthesis of testosterone was found in the tumour tissue, and the conversion of either precursor to testosterone was considerably less than in the normal testis. Suggestive evidence is presented for the occurrence of steroid-specific 17α-hydroxylase and 3β-hydroxysteroid dehydrogenase-isomerase systems in canine testicular tissue. The formation of sulphates of pregnenolone and DHA was shown both in normal and in neoplastic tissues and, in addition, the tumour either formed the sulphate of 17α-hydroxypregnenolone or caused the 17α-hydroxylation of pregnenolone sulphate.

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