Purification and Characterization of Hepatic Aldehyde Oxidase in Male and Female Mice

1997 ◽  
Vol 338 (1) ◽  
pp. 29-34 ◽  
Author(s):  
Shin'ichi Yoshihara ◽  
Kiyoshi Tatsumi
Keyword(s):  
Aldehyde Oxidase ◽  
Purification And Characterization ◽  
Male And Female ◽  
Female Mice

scholarly journals Purification and characterization of an aldehyde oxidase fromPseudomonassp. KY 4690

2003 ◽  
Vol 229 (1) ◽  
pp. 31-36 ◽  
Author(s):  
Hiroyuki Uchida ◽  
Daisaku Kondo ◽  
Ayako Yamashita ◽  
Yukio Nagaosa ◽  
Takeshi Sakurai ◽  
...  
Keyword(s):  
Aldehyde Oxidase ◽  
Purification And Characterization

scholarly journals Characterization of the immune response in male and female mice following lipopolysaccharide‐induced systemic inflammation (1096.10)

2014 ◽  
Vol 28 (S1) ◽  
Author(s):  
Nina Bubalo ◽  
Peter Nguyen ◽  
Tuan Nguyen ◽  
Tzvia Abramson ◽  
Katherine Wilkinson
Keyword(s):  
Immune Response ◽  
Systemic Inflammation ◽  
Male And Female ◽  
Female Mice

Abstract 628: Efficient Excretion of Xenosterols in the Absence of Abcg5/Abcg8

2016 ◽  
Vol 36 (suppl_1) ◽  
Author(s):  
Shailendra B Patel
Keyword(s):  
Body Weight ◽  
Plant Sterols ◽  
Whole Body ◽  
Pathological Changes ◽  
Rapid Loss ◽  
Male And Female ◽  
Female Mice ◽  
Kinetics Of ◽  
Sterol Trafficking

Hypothesis: Xenosterol excretion by the mammalian body is wholly dependent on Abcg5/Abcg8 function. Methods: To test our hypothesis, we loaded Abcg8-/- mice with dietary plant sterols until they manifested biochemical (elevated plant sterols) and pathological changes (poor body weight, macrothrombocytopenia). All dietary xenosterols were eliminated from the diet and kinetics of xenosterol loss monitored over the ensuing 16 days, monitoring plasma, bile, and stool losses, as well as whole body sterol determinations. Results: After loading Abcg8-/- mice with plant sterols, plasma sitosterol levels in both male and female mice averaged 80mg/dL. Surprisingly, there was rapid loss of xenosterols from blood as well as tissues (liver, whole body), with losses of xenosterols detected in bile and feces. By day 16, stool xenosterols were almost undetectable and reflected the dramatic loss of whole body xenosterols. Conclusions: Our data refute our hypothesis. Although loss of sterolin function leads to severe xenosterolemia in both humans and mice, at least in mice, there appears to be a pathway(s) for elimination via the biliary/intestinal route. Characterization of the transporters involved may shed further light on sterol trafficking.

Purification and characterization of a new aldehyde oxidase from pseudomonas sp. AIU 362

2008 ◽  
Vol 106 (3) ◽  
pp. 297-302 ◽  
Author(s):  
Yasutaka Sasaki ◽  
Kimiyasu Isobe ◽  
Michihiko Kataoka ◽  
Jun Ogawa ◽  
Akira Iwasaki ◽  
...  
Keyword(s):  
Aldehyde Oxidase ◽  
Pseudomonas Sp ◽  
Purification And Characterization

scholarly journals Characterization of changes in muscle afferent response to stretch following inflammation in male and female mice (1128.1)

2014 ◽  
Vol 28 (S1) ◽  
Author(s):  
Anusha Allawala ◽  
Stephanie Behnke ◽  
Dasha Zaytseva ◽  
Katherine Wilkinson
Keyword(s):  
Male And Female ◽  
Female Mice ◽  
Muscle Afferent ◽  
Afferent Response

scholarly journals cDNA Cloning, Sequencing, and Characterization of Male and Female Rat Liver Aldehyde Oxidase (rAOX1)

1999 ◽  
Vol 274 (6) ◽  
pp. 3878-3886 ◽  
Author(s):  
Richard M. Wright ◽  
Daniel A. Clayton ◽  
Mary G. Riley ◽  
James L. McManaman ◽  
John E. Repine
Keyword(s):  
Cdna Cloning ◽  
Rat Liver ◽  
Aldehyde Oxidase ◽  
Female Rat ◽  
Male And Female
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