A Bile Acid Protects against Motor and Cognitive Deficits and Reduces Striatal Degeneration in the 3-Nitropropionic Acid Model of Huntington's Disease

C.Dirk Keene; Cecilia M.P. Rodrigues; Tacjana Eich; Cheryle Linehan-Stieers; Anna Abt; Betsy T. Kren; Clifford J. Steer; Walter C. Low

doi:10.1006/exnr.2001.7755

A Bile Acid Protects against Motor and Cognitive Deficits and Reduces Striatal Degeneration in the 3-Nitropropionic Acid Model of Huntington's Disease

Experimental Neurology ◽

10.1006/exnr.2001.7755 ◽

2001 ◽

Vol 171 (2) ◽

pp. 351-360 ◽

Cited By ~ 70

Author(s):

C.Dirk Keene ◽

Cecilia M.P. Rodrigues ◽

Tacjana Eich ◽

Cheryle Linehan-Stieers ◽

Anna Abt ◽

...

Keyword(s):

Bile Acid ◽

Huntington's Disease ◽

Huntington’S Disease ◽

Cognitive Deficits ◽

Nitropropionic Acid ◽

Striatal Degeneration ◽

3 Nitropropionic Acid

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Delayed Onset and Reduced Cognitive Deficits through Pre-Conditioning with 3-Nitropropionic Acid is Dependent on Sex and CAG Repeat Length in the R6/2 Mouse Model of Huntington’s Disease

Journal of Huntington s Disease ◽

10.3233/jhd-160189 ◽

2016 ◽

Vol 5 (1) ◽

pp. 19-32 ◽

Cited By ~ 10

Author(s):

Elizabeth A. Skillings ◽

A. Jennifer Morton

Keyword(s):

Mouse Model ◽

Huntington's Disease ◽

Huntington’S Disease ◽

Cognitive Deficits ◽

Repeat Length ◽

Cag Repeat ◽

Delayed Onset ◽

Nitropropionic Acid ◽

3 Nitropropionic Acid

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Granulocyte-colony stimulating factor attenuates striatal degeneration with activating survival pathways in 3-nitropropionic acid model of Huntington's disease

Brain Research ◽

10.1016/j.brainres.2007.11.058 ◽

2008 ◽

Vol 1194 ◽

pp. 130-137 ◽

Cited By ~ 21

Author(s):

Soon-Tae Lee ◽

Jung-Eun Park ◽

Dong-Hyun Kim ◽

Seungchan Kim ◽

Woo-Seok Im ◽

...

Keyword(s):

Huntington's Disease ◽

Huntington’S Disease ◽

Granulocyte Colony Stimulating Factor ◽

Colony Stimulating Factor ◽

Nitropropionic Acid ◽

Striatal Degeneration ◽

Survival Pathways ◽

Stimulating Factor ◽

3 Nitropropionic Acid

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3-Nitropropionic acid: a mitochondrial toxin to uncover physiopathological mechanisms underlying striatal degeneration in Huntington's disease

Journal of Neurochemistry ◽

10.1111/j.1471-4159.2005.03515.x ◽

2005 ◽

Vol 95 (6) ◽

pp. 1521-1540 ◽

Cited By ~ 236

Author(s):

Emmanuel Brouillet ◽

Carine Jacquard ◽

Nicolas Bizat ◽

David Blum

Keyword(s):

Huntington's Disease ◽

Huntington’S Disease ◽

Nitropropionic Acid ◽

Striatal Degeneration ◽

Mitochondrial Toxin ◽

3 Nitropropionic Acid

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Galantamine reduces striatal degeneration in 3-nitropropionic acid model of Huntington's disease

Neuroscience Letters ◽

10.1016/j.neulet.2008.10.020 ◽

2008 ◽

Vol 448 (1) ◽

pp. 143-147 ◽

Cited By ~ 13

Author(s):

Jung-Eun Park ◽

Soon-Tae Lee ◽

Woo-Seok Im ◽

Kon Chu ◽

Manho Kim

Keyword(s):

Huntington's Disease ◽

Huntington’S Disease ◽

Nitropropionic Acid ◽

Striatal Degeneration ◽

3 Nitropropionic Acid

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Hematopoietic Factor G-CSF Attenuates Striatal Degeneration with Activating Survival Pathways in 3-Nitropropionic Acid Model of Huntington's Disease

Biology of Blood and Marrow Transplantation ◽

10.1016/j.bbmt.2015.11.493 ◽

2016 ◽

Vol 22 (3) ◽

pp. S147

Author(s):

Manho Kim ◽

Lee Lee

Keyword(s):

Huntington's Disease ◽

Huntington’S Disease ◽

Nitropropionic Acid ◽

Striatal Degeneration ◽

Survival Pathways ◽

3 Nitropropionic Acid ◽

Factor G

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Mitochondrial toxin 3-nitropropionic acid produces startle reflex abnormalities and striatal damage in rats that model some features of Huntington's disease

Neuroscience Letters ◽

10.1016/s0304-3940(97)00482-5 ◽

1997 ◽

Vol 231 (2) ◽

pp. 103-107 ◽

Cited By ~ 39

Author(s):

M.H Kodsi ◽

N.R Swerdlow

Keyword(s):

Huntington's Disease ◽

Huntington’S Disease ◽

Startle Reflex ◽

Nitropropionic Acid ◽

Mitochondrial Toxin ◽

3 Nitropropionic Acid

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Protective effect of rivastigmine against 3-nitropropionic acid-induced Huntington's disease like symptoms: Possible behavioural, biochemical and cellular alterations

European Journal of Pharmacology ◽

10.1016/j.ejphar.2009.04.058 ◽

2009 ◽

Vol 615 (1-3) ◽

pp. 91-101 ◽

Cited By ~ 26

Author(s):

Puneet Kumar ◽

Anil Kumar

Keyword(s):

Protective Effect ◽

Huntington's Disease ◽

Huntington’S Disease ◽

Nitropropionic Acid ◽

3 Nitropropionic Acid ◽

Cellular Alterations

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P2-044: Neuroprotective role of progesterone against 3-nitropropionic-acid-induced Huntington's disease-like symptoms in rats

Alzheimer s & Dementia ◽

10.1016/j.jalz.2013.05.686 ◽

2013 ◽

Vol 9 ◽

pp. P360-P360

Author(s):

Puneet Kumar ◽

Pushpender Kumar ◽

Rahul Deshmukh ◽

PL Sharma

Keyword(s):

Huntington's Disease ◽

Huntington’S Disease ◽

Nitropropionic Acid ◽

3 Nitropropionic Acid

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Neuroprotective activity of tetramethylpyrazine against 3-nitropropionic acid induced Huntington’s disease-like symptoms in rats

Biomedicine & Pharmacotherapy ◽

10.1016/j.biopha.2018.06.079 ◽

2018 ◽

Vol 105 ◽

pp. 1254-1268 ◽

Cited By ~ 7

Author(s):

Ravi Chandra Sekhara Reddy Danduga ◽

Subba Reddy Dondapati ◽

Phani Kumar Kola ◽

Lilly Grace ◽

Rahil Vandana Bisky Tadigiri ◽

...

Keyword(s):

Huntington's Disease ◽

Huntington’S Disease ◽

Neuroprotective Activity ◽

Nitropropionic Acid ◽

3 Nitropropionic Acid

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Thymoquinone loaded solid lipid nanoparticles counteracts 3-Nitropropionic acid induced motor impairments and neuroinflammation in rat model of Huntington’s disease

Metabolic Brain Disease ◽

10.1007/s11011-018-0252-0 ◽

2018 ◽

Vol 33 (5) ◽

pp. 1459-1470 ◽

Cited By ~ 4

Author(s):

Surekha Ramachandran ◽

Sumathi Thangarajan

Keyword(s):

Huntington's Disease ◽

Huntington’S Disease ◽

Rat Model ◽

Solid Lipid Nanoparticles ◽

Lipid Nanoparticles ◽

Motor Impairments ◽

Solid Lipid ◽

Nitropropionic Acid ◽

3 Nitropropionic Acid

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