Two Paraneoplastic Syndromes in a Patient with Ovarian Cancer: Nephrotic Syndrome and Paraneoplastic Cerebellar Degeneration

2001 ◽  
Vol 80 (1) ◽  
pp. 96-98 ◽  
Author(s):  
Andrea P. Forgy ◽  
Thomas L. Ewing ◽  
John Flaningam
Keyword(s):  
Ovarian Cancer ◽  
Nephrotic Syndrome ◽  
Cerebellar Degeneration ◽  
Paraneoplastic Syndromes ◽  
Paraneoplastic Cerebellar Degeneration

scholarly journals Potential effect of intravenous immunoglobulin against paraneoplastic cerebellar degeneration in progressive ovarian cancer

2020 ◽  
Vol 34 ◽  
pp. 100649
Author(s):  
Takashi Shibata ◽  
Tetsuya Oishi ◽  
Yasunori Fukuoka ◽  
Shigeki Nishikawa ◽  
Noriaki Iizuka ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Intravenous Immunoglobulin ◽  
Potential Effect ◽  
Cerebellar Degeneration ◽  
Paraneoplastic Cerebellar Degeneration

Ovarian cancer and late onset paraneoplastic cerebellar degeneration

2008 ◽  
Vol 280 (1) ◽  
pp. 99-101 ◽  
Author(s):  
Bram H. Goldstein ◽  
Connie L. Birk ◽  
Mark Van Houten ◽  
Robert Veve ◽  
John V. Brown ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Late Onset ◽  
Cerebellar Degeneration ◽  
Paraneoplastic Cerebellar Degeneration

Paraneoplastic Cerebellar Degeneration in Occult Primary Ovarian Cancer: A Case Report and Literature Review

2020 ◽  
Vol 36 (1) ◽  
pp. 34-36
Author(s):  
Navin Kumar ◽  
Mukurdipi Ray ◽  
Kanak Lata ◽  
Durgesh Wankhede ◽  
Sandeep R. Mathur ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Case Report ◽  
Literature Review ◽  
Cerebellar Degeneration ◽  
Paraneoplastic Cerebellar Degeneration ◽  
Primary Ovarian Cancer

scholarly journals Anti-Yo Mediated Paraneoplastic Cerebellar Degeneration Associated with Pseudobulbar Affect in a Patient with Breast Cancer

2017 ◽  
Vol 2017 ◽  
pp. 1-3 ◽  
Author(s):  
Allison N. Martin ◽  
Patrick M. Dillon ◽  
David E. Jones ◽  
David R. Brenin ◽  
David A. Lapides
Keyword(s):  
Breast Cancer ◽  
Paraneoplastic Syndrome ◽  
Radical Mastectomy ◽  
Cerebellar Degeneration ◽  
Paraneoplastic Syndromes ◽  
Paraneoplastic Cerebellar Degeneration ◽  
Modified Radical Mastectomy ◽  
Stage Iiia ◽  
Pseudobulbar Affect ◽  
New Onset

Paraneoplastic cerebellar degeneration (PCD) is a rare anti-Yo mediated paraneoplastic syndromes rarely that is infrequently associated with breast cancer. We present a case of a 52-year-old female presenting with diplopia, gait instability, dysarthria, dysphagia, nystagmus, and, most notably, new onset paroxysmal episodes of uncontrollable crying concerning for pseudobulbar affect (PBA). Serologic testing showed anti-Yo antibodies. The patient was found to have stage IIIA breast cancer as the inciting cause of the paraneoplastic syndrome. The patient was treated with neoadjuvant chemotherapy, modified radical mastectomy, adjuvant Herceptin, and pertuzumab. She was given IVIG for paraneoplastic syndrome, antidepressants, and dextromethorphan-quinidine (Nuedexta), the first FDA-approved therapy for PBA. With multimodality therapy, she demonstrated significant improvement in neurologic and mood symptoms associated with PCD and PBA.

scholarly journals Paraneoplastic cerebellar degeneration associated with ovarian cancer

2012 ◽  
Vol 5 (2) ◽  
pp. 681-683 ◽  
Author(s):  
ALESSIA ERIKA RUSSO ◽  
SIMONA SCALONE ◽  
GIULIA COSTANZA LEONARDI ◽  
AURORA SCALISI ◽  
GIORGIO GIORDA ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Cerebellar Degeneration ◽  
Paraneoplastic Cerebellar Degeneration

scholarly journals Ovarian Cancer Revealed by Paraneoplastic Cerebellar Degeneration Anti-Yo Positive: A Case Report

2020 ◽  
Vol 5 (12) ◽  
pp. 635-637
Author(s):  
Hayat Erraichi ◽  
Niaina Ezra Randriamanovontsoa ◽  
Valère Litique ◽  
Jean-Marc Limacher ◽  
S. Berrad ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Ovarian Cancer ◽  
Gynecological Cancer ◽  
Cerebellar Degeneration ◽  
Small Cell ◽  
Paraneoplastic Syndromes ◽  
Tumor Treatment ◽  
Small Cell Lung ◽  
Cerebellar Syndrome ◽  
Onconeural Antibodies

Neurological paraneoplastic syndromes are rare, often associated with gynecological cancer or small cell lung cancer. This article reports a case of ovarian cancer to discuss the difficulties in the management of neurological paraneoplastic syndromes. This is a case of paraneoplastic cerebellar syndrome with anti-Yo antibodies. Neurological syndromes, testing for onconeural antibodies and testing for underlying cancer provide a basis for the diagnosis. The anti-tumor treatment constitutes the mainstay of the care.

scholarly journals Ovarian cancer revealed by paraneoplastic cerebellar degeneration: a case report

2014 ◽  
Vol 18 ◽  
Author(s):  
Fadwa Elomrani ◽  
Imane Ouziane ◽  
Saber Boutayeb ◽  
Youssef Bensouda ◽  
Hind Mrabti ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Case Report ◽  
Cerebellar Degeneration ◽  
Paraneoplastic Cerebellar Degeneration
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