Effects of Intracerebroventricular Leptin Administration on Feeding and Sexual Behaviors in Lean and Obese Female Zucker Rats

2000 ◽  
Vol 37 (4) ◽  
pp. 377-387 ◽  
Author(s):  
Adam S. Fox ◽  
Arielle Foorman ◽  
Deborah H. Olster
2021 ◽  
Vol 113 ◽  
pp. 101919
Author(s):  
Dolores Adriana Bravo Durán ◽  
Selina Jocelyn Barreda Guzmán ◽  
Angélica Trujillo Hernández ◽  
Adriana Berenice Silva Gómez

1987 ◽  
Vol 117 (7) ◽  
pp. 1291-1297 ◽  
Author(s):  
Sam J. Bhathena ◽  
Patricia Aparicio ◽  
Kenneth Revett ◽  
Nancy Voyles ◽  
Lillian Recant

1985 ◽  
Vol 248 (4) ◽  
pp. H438-H444 ◽  
Author(s):  
N. F. Paradise ◽  
C. F. Pilati ◽  
W. R. Payne ◽  
J. A. Finkelstein

We sought to determine if left ventricular (LV) function of the heart from the adult, chronically obese animal is impaired. Hearts from 50 wk-old genetically obese female Zucker rats (624 +/- 13 g) and their lean littermate controls (275 +/- 5 g) were isolated during ether anesthesia, supported metabolically by retrograde aortic perfusion (6 ml/min, 35 degrees C) with physiological solution containing suspended canine erythrocytes (hematocrit, 20%), and the ventricles were paced at 180 beats/min. A distensible, fluid-filled balloon was placed in the LV, and pressure-volume (PV) relationships were obtained. The obese and lean end-diastolic PV curves were not different, and therefore the obese and lean LV chamber compliances were similar. Comparison of the systolic PV relationships demonstrated that the obese rat's heart had a greater pressure-generating capability, which probably was a reflection of its increased LV mass (0.96 +/- 0.03 vs. 0.72 +/- 0.02 g). The calculated average meridional (or circumferential) peak systolic wall stress in the LV of the obese rat's heart, however, was significantly reduced compared with control. This diminished ability to develop systolic stress from the same end-diastolic volumes suggests that the hypertrophied LV of the middle-aged obese rat's heart is dilated or that its contractility is depressed, or both.


Biomedicines ◽  
2018 ◽  
Vol 6 (2) ◽  
pp. 55 ◽  
Author(s):  
Reza Hakkak ◽  
Clinton Gauss ◽  
Andrea Bell ◽  
Soheila Korourian

1979 ◽  
Vol 109 (12) ◽  
pp. 2085-2097 ◽  
Author(s):  
E. C. H. Van Beresteyn ◽  
M. Van Schaik ◽  
M. F. Kerkhof Mogot

2009 ◽  
Vol 23 (S1) ◽  
Author(s):  
Sharon R Inman ◽  
Yuriy Slyvka ◽  
Yelena Feldman ◽  
Felicia V Nowak

Sign in / Sign up

Export Citation Format

Share Document