Percutaneous Absorption of Salicylic Acid, Theophylline, 2,4-Dimethylamine, Diethyl Hexyl Phthalic Acid, andp-Aminobenzoic Acid in the Isolated Perfused Porcine Skin Flap Compared to Manin Vivo

Catechol reacts with boron sulfide to give 2,2′-o-phenylenedioxybis-(1,3,2-benzodioxaborole) (1) while only the hydroxyl function of salicylic acid reacts to give a quantitative yield of tris(o-carboxylphenoxy)borane (3). Phthalic acid is dehydrated to phthalic anhydride, but succinic acid and maleic acid have been found inert to the action of the boron sulfide.

Download Full-text

The Isolated Perfused Porcine Skin Flap (IPPSF)

Toxicological Sciences ◽

10.1093/toxsci/7.3.444 ◽

1986 ◽

Vol 7 (3) ◽

pp. 444-453 ◽

Cited By ~ 3

Author(s):

J. EDMOND RIVIERE ◽

KARL F. BOWMAN ◽

NANCY A. MONTEIRO-RIVIERE ◽

LYNN P. Dix ◽

MICHAEL P. CARVER

Keyword(s):

Skin Flap ◽

Porcine Skin

Download Full-text

Percutaneous Absorption of LHRH Through Porcine Skin: Effect of N-Methyl 2-Pyrrolidone and Isopropyl Myristate

Drug Development and Industrial Pharmacy ◽

10.3109/03639049709150501 ◽

1997 ◽

Vol 23 (11) ◽

pp. 1111-1114 ◽

Cited By ~ 3

Author(s):

K. S. Bhatia ◽

J. Singh

Keyword(s):

Percutaneous Absorption ◽

Skin Effect ◽

Isopropyl Myristate ◽

Porcine Skin

Download Full-text

Molecular Cocrystals of Carboxylic Acids. XV. Preparation and Characterization of Heterocyclic Base Adducts With a Series of Carboxylic Acids, and the Crystal Structures of the Adducts of 2-Aminopyrimidine With 2,6-Dihydroxybenzoic Acid, 4-Aminobenzoic Acid, Phenoxyacetic Acid, (2,4-Dichlorophenoxy)acetic Acid, (3,4-Dichlorophenoxy)-acetic Acid and Salicylic Acid, and 2-Aminopyridine With 2,6-Dihydroxybenzoic Acid

Australian Journal of Chemistry ◽

10.1071/ch9941097 ◽

1994 ◽

Vol 47 (6) ◽

pp. 1097 ◽

Cited By ~ 24

Author(s):

DE Lynch ◽

G Smith ◽

D Freney ◽

KA Byriel ◽

CHL Kennard

Keyword(s):

Acetic Acid ◽

Salicylic Acid ◽

Carboxylic Acids ◽

Phenoxyacetic Acid ◽

Aminobenzoic Acid ◽

X Ray Diffraction ◽

Dihydroxybenzoic Acid ◽

Heterocyclic Base ◽

X Ray ◽

Dichlorophenoxy Acetic Acid

The molecular adducts of the heterocyclic base 2-aminopyrimidine with the aromatic and aromatic aliphatic carboxylic acids salicylic acid, 2,6-dihydroxybenzoic acid and 4-aminobenzoic acid, phenoxyacetic acid, (2,4-dichlorophenoxy)acetic acid, and (3,4-dichlorophenoxy)acetic acid have been prepared, and their interactive modes characterized by single-crystal X-ray diffraction methods. In addition, the complexes with (4-chlorophenoxy)acetic acid, (2,3-dichlorophenoxy)acetic acid, (4-chloro-2-methylphenoxy)acetic acid and (2,4,5- trichlorophenoxy)acetic acid have been characterized by analytical methods, including infrared spectroscopy. Except for the phenoxyacetic acid adduct (2:1), all form 1:1 molecular associations in which the carboxylic acid shows a variable tendency to protonate the hetero nitrogen of the base. The 1:1 complex of 2-aminopyridine with 2,6-dihydroxybenzoic acid has also been characterized by single-crystal X-ray diffraction.

Download Full-text