Effects on peripheral nerve function

2002 ◽  
pp. 645-668
Author(s):  
H. Gerhard Vogel ◽  
Wolfgang H. Vogel ◽  
Bernward A. Schölkens ◽  
Jürgen Sandow ◽  
Günter Müller ◽  
...  
Keyword(s):  
Peripheral Nerve ◽  
Nerve Function ◽  
Peripheral Nerve Function

scholarly journals Chemotherapy-induced peripheral neuropathy: longitudinal analysis of predictors for postural control

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Jana Müller ◽  
Charlotte Kreutz ◽  
Steffen Ringhof ◽  
Maximilian Koeppel ◽  
Nikolaus Kleindienst ◽  
...  
Keyword(s):  
Peripheral Neuropathy ◽  
Peripheral Nerve ◽  
Postural Control ◽  
Action Potentials ◽  
Exercise Intervention ◽  
Cross Sectional Study ◽  
Nerve Function ◽  
Cross Sectional ◽  
Peripheral Nerve Function

AbstractImpaired postural control is often observed in response to neurotoxic chemotherapy. However, potential explanatory factors other than chemotherapy-induced peripheral neuropathy (CIPN) have not been adequately considered to date due to primarily cross-sectional study designs. Our objective was to comprehensively analyze postural control during and after neurotoxic chemotherapy, and to identify potential CIPN-independent predictors for its impairment. Postural control and CIPN symptoms (EORTC QLQ-CIPN20) were longitudinally assessed before, during and three weeks after neurotoxic chemotherapy, and in three and six months follow-up examinations (N = 54). The influence of peripheral nerve function as determined by nerve conduction studies (NCS: compound motor action potentials (CMAP) and sensory action potentials (SNAP)), physical activity, and muscle strength on the change in postural control during and after chemotherapy was analyzed by multiple linear regression adjusted for age and body mass index. Postural control, CIPN signs/symptoms, and CMAP/SNAP amplitudes significantly deteriorated during chemotherapy (p < .01). During follow-up, patients recovered from postural instabilities (p < .01), whereas CIPN signs/symptoms and pathologic NCS findings persisted compared to baseline (p < .001). The regression model showed that low CMAP and high SNAP amplitudes at baseline predicted impairment of postural control during but not after chemotherapy. Hence, pre-therapeutically disturbed somatosensory inputs may induce adaptive processes that have compensatory effects and allow recovery of postural control while CIPN signs/symptoms and pathologic peripheral nerve function persist. Baseline NCS findings in cancer patients who receive neurotoxic chemotherapy thus might assist in delineating individual CIPN risk profiles more precisely to which specific exercise intervention programs could be tailor-made.

Peripheral nerve function in patients with familial amyloid polyneuropathy after liver transplantation

Amyloid ◽  
2003 ◽  
Vol 10 (1) ◽  
pp. 17-24 ◽  
Author(s):  
Sachio Kobayashi ◽  
Hiroshi Morita ◽  
Teruko Asawa ◽  
Yo-Ichi Takei ◽  
Takao Hashimoto ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Peripheral Nerve ◽  
Familial Amyloid Polyneuropathy ◽  
Nerve Function ◽  
Amyloid Polyneuropathy ◽  
Peripheral Nerve Function

Beneficial effect of nimodipine on peripheral nerve function in aged rats

1990 ◽  
Vol 11 (4) ◽  
pp. 451-456 ◽  
Author(s):  
C VANDERZEE ◽  
T SCHUURMAN ◽  
R VANDERHOOP ◽  
J TRABER ◽  
W GISPEN
Keyword(s):  
Peripheral Nerve ◽  
Beneficial Effect ◽  
Nerve Function ◽  
Aged Rats ◽  
Peripheral Nerve Function

The Role of Schwann Cells in Peripheral Nerve Function, Injury, and Repair

2020 ◽  
pp. 1-22
Author(s):  
Christina M. A. P. Schuh ◽  
Ana Maria Sandoval-Castellanos ◽  
Cristian De Gregorio ◽  
Pamina Contreras-Kallens ◽  
John W. Haycock
Keyword(s):  
Peripheral Nerve ◽  
Schwann Cells ◽  
Nerve Function ◽  
Peripheral Nerve Function ◽  
Injury And Repair
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