Multiple Approaches for Enhancing Neural Activity to Promote Neurite Outgrowth of Retinal Explants

2019 ◽  
pp. 65-75
Author(s):  
Chuan-Chin Chiao ◽  
Chin-I Lin ◽  
Meng-Jung Lee
Keyword(s):  
Neurite Outgrowth ◽  
Neural Activity ◽  
Promote Neurite Outgrowth ◽  
Retinal Explants

scholarly journals Stimulation of neurite outgrowth in PC12 cells by EGF and KCl depolarization: a Ca(2+)-independent phenomenon.

1995 ◽  
Vol 130 (3) ◽  
pp. 701-710 ◽  
Author(s):  
M D Mark ◽  
Y Liu ◽  
S T Wong ◽  
T R Hinds ◽  
D R Storm
Keyword(s):  
Map Kinase ◽  
Neurite Outgrowth ◽  
Pc12 Cells ◽  
Kinase Activity ◽  
Neurite Growth ◽  
Intracellular Camp ◽  
Regulation Of Transcription ◽  
Promote Neurite Outgrowth ◽  
Synergistic Regulation ◽  
Stimulation Of

MAP kinase activity is necessary for growth factor induction of neurite outgrowth in PC12 cells. Although NGF and EGF both stimulate MAP kinase activity, EGF does not stimulate neurite extension. We report that EGF, in combination with KCl, stimulates neurite outgrowth in PC12 cells. This phenomenon was independent of intracellular Ca2+ increases and not due to enhancement of MAP kinase activity over that seen with EGF alone. However, EGF plus KCl increased intracellular cAMP, and other cAMP elevating agents acted synergistically with EGF to promote neurite outgrowth. Stimulation of neurite outgrowth by cAMP and EGF was blocked by inhibitors of transcription suggesting that synergistic regulation of transcription by the cAMP and MAP kinase pathways may stimulate neurite growth.

Spastin Interacts with CRMP5 to Promote Neurite Outgrowth by Controlling the Microtubule Dynamics

2018 ◽  
Vol 78 (12) ◽  
pp. 1191-1205 ◽  
Author(s):  
Zhisheng Ji ◽  
Guowei Zhang ◽  
Li Chen ◽  
Jiong Li ◽  
Yuhao Yang ◽  
...  
Keyword(s):  
Neurite Outgrowth ◽  
Microtubule Dynamics ◽  
Promote Neurite Outgrowth

Overexpression of nerve growth factor in peritoneal fluid from women with endometriosis may promote neurite outgrowth in endometriotic lesions

2011 ◽  
Vol 95 (3) ◽  
pp. 1123-1126 ◽  
Author(s):  
Maria Luisa Barcena de Arellano ◽  
Julia Arnold ◽  
Filiberto Vercellino ◽  
Vito Chiantera ◽  
Achim Schneider ◽  
...  
Keyword(s):  
Nerve Growth Factor ◽  
Growth Factor ◽  
Neurite Outgrowth ◽  
Peritoneal Fluid ◽  
Nerve Growth ◽  
Promote Neurite Outgrowth

Guaifenesin Derivatives Promote Neurite Outgrowth and Protect Diabetic Mice from Neuropathy

2013 ◽  
Vol 56 (12) ◽  
pp. 5071-5078 ◽  
Author(s):  
Mallinath B. Hadimani ◽  
Meena K. Purohit ◽  
Chandrashaker Vanampally ◽  
Randy Van der Ploeg ◽  
Victor Arballo ◽  
...  
Keyword(s):  
Neurite Outgrowth ◽  
Diabetic Mice ◽  
Promote Neurite Outgrowth
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