Minimally Invasive Intraluminal Tumor Ablation

Solid focal and oligometastatic malignancies are appropriate targets for minimally invasive ablative procedures. Thermochemical ablation is an experimental minimally invasive procedure, which exploits certain features of current thermal and chemical tumor ablation therapies. Engineering principles have been used to design a device, which has been research-proven-capable of coagulating tissue through the combination of a thermal and chemical insult. This interventional device completes this assignment by separately guiding the flow of chemical reagents, drawn from auxiliary systems, to a point at the distal tip of an assembled apparatus. At this position, the respective flow-streams converge and undergo an exothermic reaction to produce a heated, hyperosmolar solute, which serves to ablate the targeted tissue. Ex and in vivo studies have confirmed the utility of this device and the physiologic toleration of this interventional concept.

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An injectable ionic hydrogel inducing high temperature hyperthermia for microwave tumor ablation

Journal of Materials Chemistry B ◽

10.1039/c7tb00556c ◽

2017 ◽

Vol 5 (22) ◽

pp. 4110-4120 ◽

Cited By ~ 20

Author(s):

Jingyun Wang ◽

Dan Wang ◽

Hao Yan ◽

Lei Tao ◽

Yen Wei ◽

...

Keyword(s):

High Temperature ◽

Minimally Invasive ◽

Clinical Significance ◽

Minimally Invasive Therapy ◽

Tumor Ablation ◽

Invasive Therapy

Microwave tumor ablation is of clinical significance and has been considered as a promising cancer minimally invasive therapy.

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IDENTIFICATION OF TEMPERATURE-DEPENDENT PARAMETERS IN LASER-INTERSTITIAL THERMO THERAPY

Mathematical Models and Methods in Applied Sciences ◽

10.1142/s0218202512500194 ◽

2012 ◽

Vol 22 (09) ◽

pp. 1250019 ◽

Cited By ~ 12

Author(s):

OLIVER TSE ◽

RENÉ PINNAU ◽

NORBERT SIEDOW

Keyword(s):

Optimal Control ◽

Optimal Control Problem ◽

Minimally Invasive ◽

Control Problem ◽

Thermal Denaturation ◽

Tumor Ablation ◽

Percutaneous Technique ◽

Temperature Dependent ◽

Laser Applications ◽

Irradiation Planning

Laser-induced thermotherapy (LITT) is an established minimally invasive percutaneous technique of tumor ablation. Nevertheless, there is a need to predict the effect of laser applications and optimize irradiation planning in LITT. Optical attributes (attenuation, absorption, scattering) change due to thermal denaturation. The work presents the possibility to identify these temperature-dependent parameters from given temperature measurements via an optimal control problem. The solvability of the optimal control problem is analyzed and results of successful implementations are shown.

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Considerations in Dysphagia Management Following Esophagectomy

Perspectives of the ASHA Special Interest Groups ◽

10.1044/persp1.sig13.169 ◽

2016 ◽

Vol 1 (13) ◽

pp. 169-176

Author(s):

Lisa M. Evangelista ◽

James L. Coyle

Keyword(s):

Esophageal Cancer ◽

Minimally Invasive ◽

Minimally Invasive Surgical Procedures ◽

Esophageal Resection ◽

Minimally Invasive Surgical ◽

Operative Complications ◽

Swallowing Difficulties ◽

Epidemiological Impact ◽

Invasive Techniques ◽

Management Of Dysphagia

Esophageal cancer is the sixth leading cause of death from cancer worldwide. Esophageal resection is the mainstay treatment for cancers of the esophagus. While curative, surgical resection may result in swallowing difficulties that require intervention from speech-language pathologists (SLPs). Minimally invasive surgical procedures for esophageal resection have aimed to reduce morbidity and mortality associated with more invasive techniques. Both intra-operative and post-operative complications, regardless of the surgical approach, can result in dysphagia. This article will review the epidemiological impact of esophageal cancers, operative complications resulting in dysphagia, and clinical assessment and management of dysphagia pertinent to esophageal resection.

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