Clinical Evaluation of Drug Candidates

1987 ◽  
pp. 327-350 ◽  
Author(s):  
Scott A. Reines ◽  
Dick Fong
Keyword(s):  
Clinical Evaluation ◽  
Drug Candidates

scholarly journals In-Silico Interaction of Hydroxychloroquine Drug with Various Proteins of Coronavirus (SARS-CoV-2): A Computational Approaches to Combat COVID-19

2020 ◽  
Author(s):  
Rishee Kalaria ◽  
Hiren K. Patel
Keyword(s):  
Drug Interactions ◽  
Binding Affinity ◽  
Clinical Evaluation ◽  
In Silico ◽  
Docking Study ◽  
Spike Glycoprotein ◽  
Computational Approaches ◽  
Drug Candidates ◽  
Novel Drug

<p><i>In silico</i> docking study showed that hydroxychloroquine drug interactions with SARS-CoV2 show a higher binding affinity with spike glycoprotein and PLPRO protein compared to protein envelopes that could be ladder for potential targeting and synthesizing of another aniviral drug. <i>In silico</i> methods used in this study, the efficacy of a wide variety of repositioned and/or novel drug candidates could also be tested prior to clinical evaluation.</p>

scholarly journals In-Silico Interaction of Hydroxychloroquine Drug with Various Proteins of Coronavirus (SARS-CoV-2): A Computational Approaches to Combat COVID-19

2020 ◽  
Author(s):  
Rishee Kalaria ◽  
Hiren K. Patel
Keyword(s):  
Drug Interactions ◽  
Binding Affinity ◽  
Clinical Evaluation ◽  
In Silico ◽  
Docking Study ◽  
Spike Glycoprotein ◽  
Computational Approaches ◽  
Drug Candidates ◽  
Novel Drug

<p><i>In silico</i> docking study showed that hydroxychloroquine drug interactions with SARS-CoV2 show a higher binding affinity with spike glycoprotein and PLPRO protein compared to protein envelopes that could be ladder for potential targeting and synthesizing of another aniviral drug. <i>In silico</i> methods used in this study, the efficacy of a wide variety of repositioned and/or novel drug candidates could also be tested prior to clinical evaluation.</p>

The Clinical Evaluation of Prolapse of the Gastric Mucosa into the Duodenum

1952 ◽  
Vol 22 (1) ◽  
pp. 80-102 ◽  
Author(s):  
Maurice Feldman ◽  
Samuel Morrison ◽  
Philip Myers
Keyword(s):  
Gastric Mucosa ◽  
Clinical Evaluation

Structural Alterations in the Clinical Evaluation of Cirrhosis

1956 ◽  
Vol 30 (3) ◽  
pp. 357-372 ◽  
Author(s):  
Fenton Schaffner ◽  
Hans Popper ◽  
Mario Dalla Torre
Keyword(s):  
Clinical Evaluation ◽  
Structural Alterations
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